Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX D Clynes, C Jelinska, B Xella, H Ayyub, C Scott, M Mitson, S Taylor, ... Nature communications 6 (1), 7538, 2015 | 305 | 2015 |
Molecular basis for the recognition of phosphorylated and phosphoacetylated histone h3 by 14-3-3 N Macdonald, JPI Welburn, MEM Noble, A Nguyen, MB Yaffe, D Clynes, ... Molecular cell 20 (2), 199-211, 2005 | 291 | 2005 |
Combinatorial readout of histone H3 modifications specifies localization of ATRX to heterochromatin S Eustermann, JC Yang, MJ Law, R Amos, LM Chapman, C Jelinska, ... Nature structural & molecular biology 18 (7), 777-782, 2011 | 226 | 2011 |
The chromatin remodeller ATRX: a repeat offender in human disease D Clynes, DR Higgs, RJ Gibbons Trends in biochemical sciences 38 (9), 461-466, 2013 | 150 | 2013 |
The chromatin remodelling factor ATRX suppresses R‐loops in transcribed telomeric repeats DTT Nguyen, HPJ Voon, B Xella, C Scott, D Clynes, C Babbs, H Ayyub, ... EMBO reports 18 (6), 914-928, 2017 | 132 | 2017 |
ATRX dysfunction induces replication defects in primary mouse cells D Clynes, C Jelinska, B Xella, H Ayyub, S Taylor, M Mitson, CZ Bachrati, ... PloS one 9 (3), e92915, 2014 | 124 | 2014 |
14-3-3 interaction with histone H3 involves a dual modification pattern of phosphoacetylation W Walter, D Clynes, Y Tang, R Marmorstein, J Mellor, SL Berger Molecular and cellular biology, 2008 | 110 | 2008 |
A glimpse into the epigenetic landscape of gene regulation J Mellor, P Dudek, D Clynes Current opinion in genetics & development 18 (2), 116-122, 2008 | 85 | 2008 |
ATRX and the replication of structured DNA D Clynes, RJ Gibbons Current opinion in genetics & development 23 (3), 289-294, 2013 | 59 | 2013 |
Lysine acetylation controls local protein conformation by influencing proline isomerization FS Howe, I Boubriak, MJ Sale, A Nair, D Clynes, A Grijzenhout, ... Molecular cell 55 (5), 733-744, 2014 | 45 | 2014 |
JAK2V617F promotes replication fork stalling with disease-restricted impairment of the intra-S checkpoint response E Chen, JS Ahn, CE Massie, D Clynes, AL Godfrey, J Li, HJ Park, ... Proceedings of the National Academy of Sciences 111 (42), 15190-15195, 2014 | 44 | 2014 |
Nucleosome remodeling and transcriptional repression are distinct functions of Isw1 in Saccharomyces cerevisiae M Pinskaya, A Nair, D Clynes, A Morillon, J Mellor Molecular and cellular biology, 2009 | 30 | 2009 |
Alternative lengthening of telomeres in pediatric cancer: mechanisms to therapies T Kent, D Gracias, S Shepherd, D Clynes Frontiers in Oncology 9, 1518, 2020 | 21 | 2020 |
Alternative lengthening of telomeres: lessons to be learned from telomeric DNA double-strand break repair T Kent, D Clynes Genes 12 (11), 1734, 2021 | 10 | 2021 |
Induction of the alternative lengthening of telomeres pathway by trapping of proteins on DNA AM Rose, T Goncalves, S Cunniffe, HEB Geiller, T Kent, S Shepherd, ... Nucleic Acids Research 51 (13), 6509-6527, 2023 | 7 | 2023 |
Loss of FAM111B protease mutated in hereditary fibrosing poikiloderma negatively regulates telomere length M Kliszczak, D Moralli, JD Jankowska, P Bryjka, L Subha Meem, ... Frontiers in Cell and Developmental Biology 11, 1175069, 2023 | 2 | 2023 |
Loss of FAM111B protease mutated in hereditary fibrosing poikiloderma syndrome negatively regulates telomere length M Kliszczak, D Moralli, JD Jankowska, P Bryjka, LS Meem, T Goncalves, ... bioRxiv, 2023.01. 22.525054, 2023 | 1 | 2023 |
Induction of the ALT pathway requires loss of ATRX-DAXX in concert with genotoxic lesions at telomeres D Clynes, T Goncalves, T Kent, S Shepherd, S Cunniffe, S Kim, ... | 1 | 2021 |
REACTIVE OXYGEN SPECIES, PROTEIN TRAPPING AND CANCER: NOVEL INSIGHTS FROM IN VITRO STUDIES A Rose, T Goncalves, T Ma, A Rose, S Cunniffe, T Humphrey, ... PEDIATRIC BLOOD & CANCER 70, 2023 | | 2023 |
NAR Breakthrough Article Induction of the alternative lengthening of telomeres AM Rose, T Goncalves, S Cunniffe, HEB Geiller, T Kent, S Shepherd, ... Nucleic Acids Research, 6509-6527, 2023 | | 2023 |