Complement activation by heme as a secondary hit for atypical hemolytic uremic syndrome M Frimat, F Tabarin, JD Dimitrov, C Poitou, L Halbwachs-Mecarelli, ... Blood, The Journal of the American Society of Hematology 122 (2), 282-292, 2013 | 256 | 2013 |
Molecular basis for bacterial peptidoglycan recognition by LysM domains S Mesnage, M Dellarole, NJ Baxter, JB Rouget, JD Dimitrov, N Wang, ... Nature communications 5 (1), 4269, 2014 | 214 | 2014 |
Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome LT Roumenina, M Jablonski, C Hue, J Blouin, JD Dimitrov, ... Blood, The Journal of the American Society of Hematology 114 (13), 2837-2845, 2009 | 190 | 2009 |
Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles NS Merle, A Grunenwald, H Rajaratnam, V Gnemmi, M Frimat, ... JCI insight 3 (12), 2018 | 162 | 2018 |
Heme: modulator of plasma systems in hemolytic diseases LT Roumenina, J Rayes, S Lacroix-Desmazes, JD Dimitrov Trends in molecular medicine 22 (3), 200-213, 2016 | 138 | 2016 |
P-selectin drives complement attack on endothelium during intravascular hemolysis in TLR-4/heme-dependent manner NS Merle, R Paule, J Leon, M Daugan, T Robe-Rybkine, V Poillerat, ... Proceedings of the National Academy of Sciences 116 (13), 6280-6285, 2019 | 109 | 2019 |
Antibody polyreactivity in health and disease: statu variabilis JD Dimitrov, C Planchais, LT Roumenina, TL Vassilev, SV Kaveri, ... The Journal of Immunology 191 (3), 993-999, 2013 | 104 | 2013 |
Antibodies use heme as a cofactor to extend their pathogen elimination activity and to acquire new effector functions JD Dimitrov, LT Roumenina, VR Doltchinkova, NM Mihaylova, ... Journal of Biological Chemistry 282 (37), 26696-26706, 2007 | 96 | 2007 |
Natural antibodies: from first-line defense against pathogens to perpetual immune homeostasis MS Maddur, S Lacroix-Desmazes, JD Dimitrov, MD Kazatchkine, J Bayry, ... Clinical Reviews in Allergy & Immunology 58, 213-228, 2020 | 90 | 2020 |
Intravenous immunoglobulin induces proliferation and immunoglobulin synthesis from B cells of patients with common variable immunodeficiency: a mechanism underlying the … J Bayry, EM Fournier, MS Maddur, J Vani, B Wootla, S Sibéril, JD Dimitrov, ... Journal of autoimmunity 36 (1), 9-15, 2011 | 89 | 2011 |
Breaking the law: unconventional strategies for antibody diversification A Kanyavuz, A Marey-Jarossay, S Lacroix-Desmazes, JD Dimitrov Nature Reviews Immunology 19 (6), 355-368, 2019 | 85 | 2019 |
The interaction between factor H and VWF increases factor H cofactor activity and regulates VWF prothrombotic status J Rayes, LT Roumenina, JD Dimitrov, Y Repessé, M Ing, O Christophe, ... Blood, The Journal of the American Society of Hematology 123 (1), 121-125, 2014 | 85 | 2014 |
Ferrous ions and reactive oxygen species increase antigen-binding and anti-inflammatory activities of immunoglobulin G JD Dimitrov, ND Ivanovska, S Lacroix-Desmazes, VR Doltchinkova, ... Journal of Biological Chemistry 281 (1), 439-446, 2006 | 84 | 2006 |
TCR stimulation drives cleavage and shedding of the ITIM receptor CD31 G Fornasa, E Groyer, M Clement, J Dimitrov, C Compain, AT Gaston, ... The Journal of Immunology 184 (10), 5485-5492, 2010 | 77 | 2010 |
Heme induces human and mouse platelet activation through C-type-lectin-like receptor-2 JH Bourne, M Colicchia, Y Di, E Martin, A Slater, LT Roumenina, ... Haematologica 106 (2), 626, 2021 | 69 | 2021 |
Heme interacts with c1q and inhibits the classical complement pathway LT Roumenina, M Radanova, BP Atanasov, KT Popov, SV Kaveri, ... Journal of Biological Chemistry 286 (18), 16459-16469, 2011 | 69 | 2011 |
Important parameters for evaluation of antibody avidity by immunosorbent assay JD Dimitrov, S Lacroix-Desmazes, SV Kaveri Analytical biochemistry 418 (1), 149-151, 2011 | 61 | 2011 |
Metrics: journal's impact factor skewed by a single paper JD Dimitrov, SV Kaveri, J Bayry Nature 466 (7303), 179-179, 2010 | 60 | 2010 |
Exposure of IgG to an acidic environment results in molecular modifications and in enhanced protective activity in sepsis IK Djoumerska‐Alexieva, JD Dimitrov, EN Voynova, S Lacroix‐Desmazes, ... The FEBS Journal 277 (14), 3039-3050, 2010 | 57 | 2010 |
Regulation of immune responses to protein therapeutics by transplacental induction of T cell tolerance N Gupta, S Culina, Y Meslier, J Dimitrov, C Arnoult, S Delignat, ... Science translational medicine 7 (275), 275ra21-275ra21, 2015 | 55 | 2015 |