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Gerard Griffioen
Gerard Griffioen
CSO reMYND
在 ext.remynd.com 的电子邮件经过验证 - 首页
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PKA and Sch9 control a molecular switch important for the proper adaptation to nutrient availability
J Roosen, K Engelen, K Marchal, J Mathys, G Griffioen, E Cameroni, ...
Molecular microbiology 55 (3), 862-880, 2005
2352005
Molecular mechanisms controlling the localisation of protein kinase A
G Griffioen, JM Thevelein
Current Genetics 41, 199-207, 2002
1492002
Characterization of α‐synuclein aggregation and synergistic toxicity with protein tau in yeast
P Zabrocki, K Pellens, T Vanhelmont, T Vandebroek, G Griffioen, S Wera, ...
The FEBS journal 272 (6), 1386-1400, 2005
1462005
Nutritional control of nucleocytoplasmic localization of cAMP-dependent protein kinase catalytic and regulatory subunits in Saccharomyces cerevisiae
G Griffioen, P Anghileri, E Imre, MD Baroni, H Ruis
Journal of Biological Chemistry 275 (2), 1449-1456, 2000
1462000
Nucleocytoplasmic distribution of budding yeast protein kinase A regulatory subunit Bcy1 requires Zds1 and is regulated by Yak1-dependent phosphorylation of its targeting domain
G Griffioen, P Branduardi, A Ballarini, P Anghileri, J Norbeck, MD Baroni, ...
Molecular and cellular biology 21 (2), 511-523, 2001
1402001
A yeast-based model of α-synucleinopathy identifies compounds with therapeutic potential
G Griffioen, H Duhamel, N Van Damme, K Pellens, P Zabrocki, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1762 (3), 312-318, 2006
1132006
Glucose-triggered signalling in Saccharomyces cerevisiae: different requirements for sugar phosphorylation between cells grown on glucose and those grown on non-fermentable …
MB Pernambuco, J Winderickx, M Crauwels, G Griffioen, WH Mager, ...
Microbiology 142 (7), 1775-1782, 1996
911996
Growth-related expression of ribosomal protein genes in Saccharomyces cerevisiae
LS Kraakman, G Griffioen, S Zerp, P Groeneveld, JM Thevelein, ...
Molecular and General Genetics MGG 239, 196-204, 1993
881993
Evaluation of the Vitotox™ and RadarScreen assays for the rapid assessment of genotoxicity in the early research phase of drug development
WMA Westerink, JCR Stevenson, A Lauwers, G Griffioen, GJ Horbach, ...
Mutation Research/Genetic Toxicology and Environmental Mutagenesis 676 (1-2 …, 2009
872009
Feedback inhibition on cell wall integrity signaling by Zds1 involves Gsk3 phosphorylation of a cAMP-dependent protein kinase regulatory subunit
G Griffioen, S Swinnen, JM Thevelein
Journal of Biological Chemistry 278 (26), 23460-23471, 2003
642003
Transcription activation of yeast ribosomal protein genes requires additional elements apart from binding sites for Abf1p or Rap1p
PM Gonçalves, G Griffioen, R Minnee, M Bosma, LS Kraakman, ...
Nucleic acids research 23 (9), 1475-1480, 1995
601995
Nutritional upshift response of ribosomal protein gene transcription in Saccharomyces cerevisiae
G Griffioen, WH Mager, RJ Planta
FEMS microbiology letters 123 (1-2), 137-144, 1994
461994
Ribosomal protein gene transcription in Saccharomyces cerevisiae shows a biphasic response to nutritional changes
G Griffioen, RJ Laan, WH Mager, RJ Planta
Microbiology 142 (8), 2279-2287, 1996
451996
Signalling pathways leading to transcriptional regulation of genes involved in the activation of glycolysis in yeast
PM Gonçalves, G Griffioen, J Paul Bebelman, RJ Planta
Molecular microbiology 25 (3), 483-493, 1997
431997
Substituted 2-aminothiazoles are exceptional inhibitors of neuronal degeneration in tau-driven models of Alzheimer’s disease
I Lagoja, C Pannecouque, G Griffioen, S Wera, VM Rojasdelaparra, ...
European journal of pharmaceutical sciences 43 (5), 386-392, 2011
392011
Pathological Hallmarks, Clinical Parallels, and Value for Drug Testing in Alzheimer′ s Disease of the APP [V717I] London Transgenic Mouse Model
A Tanghe, A Termont, P Merchiers, S Schilling, HU Demuth, L Scrocchi, ...
International journal of Alzheimer’s disease 2010 (1), 417314, 2010
382010
Cytosolic calcium: Judge, jury and executioner of neurodegeneration in Alzheimer's disease and beyond
EK Webber, M Fivaz, GE Stutzmann, G Griffioen
Alzheimer's & Dementia 19 (8), 3701-3717, 2023
202023
Indole amide derivatives and related compounds for use in the treatment of neurodegenerative diseases
G Griffioen, T Van Dooren, VR DE LA PARRA, A Marchand, S Allasia, ...
US Patent 10,117,850, 2018
202018
Compounds for the treatment of neurodegenerative diseases
G Griffioen, T Van Dooren, VR De La Parra, A Marchand, S Alassia, ...
US Patent 9,284,271, 2016
172016
Pharmacological modulation of septins restores calcium homeostasis and is neuroprotective in models of Alzheimer’s disease
K Princen, T Van Dooren, M van Gorsel, N Louros, X Yang, M Dumbacher, ...
Science 384 (6699), eadd6260, 2024
132024
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