PKA and Sch9 control a molecular switch important for the proper adaptation to nutrient availability J Roosen, K Engelen, K Marchal, J Mathys, G Griffioen, E Cameroni, ... Molecular microbiology 55 (3), 862-880, 2005 | 235 | 2005 |
Molecular mechanisms controlling the localisation of protein kinase A G Griffioen, JM Thevelein Current Genetics 41, 199-207, 2002 | 149 | 2002 |
Characterization of α‐synuclein aggregation and synergistic toxicity with protein tau in yeast P Zabrocki, K Pellens, T Vanhelmont, T Vandebroek, G Griffioen, S Wera, ... The FEBS journal 272 (6), 1386-1400, 2005 | 146 | 2005 |
Nutritional control of nucleocytoplasmic localization of cAMP-dependent protein kinase catalytic and regulatory subunits in Saccharomyces cerevisiae G Griffioen, P Anghileri, E Imre, MD Baroni, H Ruis Journal of Biological Chemistry 275 (2), 1449-1456, 2000 | 146 | 2000 |
Nucleocytoplasmic distribution of budding yeast protein kinase A regulatory subunit Bcy1 requires Zds1 and is regulated by Yak1-dependent phosphorylation of its targeting domain G Griffioen, P Branduardi, A Ballarini, P Anghileri, J Norbeck, MD Baroni, ... Molecular and cellular biology 21 (2), 511-523, 2001 | 140 | 2001 |
A yeast-based model of α-synucleinopathy identifies compounds with therapeutic potential G Griffioen, H Duhamel, N Van Damme, K Pellens, P Zabrocki, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1762 (3), 312-318, 2006 | 113 | 2006 |
Glucose-triggered signalling in Saccharomyces cerevisiae: different requirements for sugar phosphorylation between cells grown on glucose and those grown on non-fermentable … MB Pernambuco, J Winderickx, M Crauwels, G Griffioen, WH Mager, ... Microbiology 142 (7), 1775-1782, 1996 | 91 | 1996 |
Growth-related expression of ribosomal protein genes in Saccharomyces cerevisiae LS Kraakman, G Griffioen, S Zerp, P Groeneveld, JM Thevelein, ... Molecular and General Genetics MGG 239, 196-204, 1993 | 88 | 1993 |
Evaluation of the Vitotox™ and RadarScreen assays for the rapid assessment of genotoxicity in the early research phase of drug development WMA Westerink, JCR Stevenson, A Lauwers, G Griffioen, GJ Horbach, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 676 (1-2 …, 2009 | 87 | 2009 |
Feedback inhibition on cell wall integrity signaling by Zds1 involves Gsk3 phosphorylation of a cAMP-dependent protein kinase regulatory subunit G Griffioen, S Swinnen, JM Thevelein Journal of Biological Chemistry 278 (26), 23460-23471, 2003 | 64 | 2003 |
Transcription activation of yeast ribosomal protein genes requires additional elements apart from binding sites for Abf1p or Rap1p PM Gonçalves, G Griffioen, R Minnee, M Bosma, LS Kraakman, ... Nucleic acids research 23 (9), 1475-1480, 1995 | 60 | 1995 |
Nutritional upshift response of ribosomal protein gene transcription in Saccharomyces cerevisiae G Griffioen, WH Mager, RJ Planta FEMS microbiology letters 123 (1-2), 137-144, 1994 | 46 | 1994 |
Ribosomal protein gene transcription in Saccharomyces cerevisiae shows a biphasic response to nutritional changes G Griffioen, RJ Laan, WH Mager, RJ Planta Microbiology 142 (8), 2279-2287, 1996 | 45 | 1996 |
Signalling pathways leading to transcriptional regulation of genes involved in the activation of glycolysis in yeast PM Gonçalves, G Griffioen, J Paul Bebelman, RJ Planta Molecular microbiology 25 (3), 483-493, 1997 | 43 | 1997 |
Substituted 2-aminothiazoles are exceptional inhibitors of neuronal degeneration in tau-driven models of Alzheimer’s disease I Lagoja, C Pannecouque, G Griffioen, S Wera, VM Rojasdelaparra, ... European journal of pharmaceutical sciences 43 (5), 386-392, 2011 | 39 | 2011 |
Pathological Hallmarks, Clinical Parallels, and Value for Drug Testing in Alzheimer′ s Disease of the APP [V717I] London Transgenic Mouse Model A Tanghe, A Termont, P Merchiers, S Schilling, HU Demuth, L Scrocchi, ... International journal of Alzheimer’s disease 2010 (1), 417314, 2010 | 38 | 2010 |
Cytosolic calcium: Judge, jury and executioner of neurodegeneration in Alzheimer's disease and beyond EK Webber, M Fivaz, GE Stutzmann, G Griffioen Alzheimer's & Dementia 19 (8), 3701-3717, 2023 | 20 | 2023 |
Indole amide derivatives and related compounds for use in the treatment of neurodegenerative diseases G Griffioen, T Van Dooren, VR DE LA PARRA, A Marchand, S Allasia, ... US Patent 10,117,850, 2018 | 20 | 2018 |
Compounds for the treatment of neurodegenerative diseases G Griffioen, T Van Dooren, VR De La Parra, A Marchand, S Alassia, ... US Patent 9,284,271, 2016 | 17 | 2016 |
Pharmacological modulation of septins restores calcium homeostasis and is neuroprotective in models of Alzheimer’s disease K Princen, T Van Dooren, M van Gorsel, N Louros, X Yang, M Dumbacher, ... Science 384 (6699), eadd6260, 2024 | 13 | 2024 |