Combinatorial microRNA target predictions A Krek, D Grün, MN Poy, R Wolf, L Rosenberg, EJ Epstein, ... Nature genetics 37 (5), 495-500, 2005 | 5666 | 2005 |
Silencing of microRNAs in vivo with ‘antagomirs’ J Krützfeldt, N Rajewsky, R Braich, KG Rajeev, T Tuschl, M Manoharan, ... nature 438 (7068), 685-689, 2005 | 5074 | 2005 |
A pancreatic islet-specific microRNA regulates insulin secretion MN Poy, L Eliasson, J Krutzfeldt, S Kuwajima, X Ma, PE Macdonald, ... Nature 432 (7014), 226-230, 2004 | 2719 | 2004 |
Leptin activation of Stat3 in the hypothalamus of wild–type and ob/ob mice but not db/db mice C Vaisse, JL Halaas, CM Horvath, JE Darnell Jr, M Stoffel, JM Friedman Nature genetics 14 (1), 95-97, 1996 | 1380 | 1996 |
Mechanisms and optimization of in vivo delivery of lipophilic siRNAs C Wolfrum, S Shi, KN Jayaprakash, M Jayaraman, G Wang, RK Pandey, ... Nature biotechnology 25 (10), 1149-1157, 2007 | 1127 | 2007 |
MicroRNAs 103 and 107 regulate insulin sensitivity M Trajkovski, J Hausser, J Soutschek, B Bhat, A Akin, M Zavolan, ... Nature 474 (7353), 649-653, 2011 | 1121 | 2011 |
Familial hyperglycemia due to mutations in glucokinase--definition of a subtype of diabetes mellitus P Froguel, H Zouali, N Vionnet, G Velho, M Vaxillaire, F Sun, S Lesage, ... New England Journal of Medicine 328 (10), 697-702, 1993 | 1078 | 1993 |
A skin microRNA promotes differentiation by repressing ‘stemness’ R Yi, MN Poy, M Stoffel, E Fuchs Nature 452 (7184), 225-229, 2008 | 937 | 2008 |
miR-375 maintains normal pancreatic α-and β-cell mass MN Poy, J Hausser, M Trajkovski, M Braun, S Collins, P Rorsman, ... Proceedings of the National Academy of Sciences 106 (14), 5813-5818, 2009 | 918 | 2009 |
Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus N Vionnet, M Stoffel, J Takeda, K Yasuda, GI Bell, H Zouali, S Lesage, ... Nature 356 (6371), 721-722, 1992 | 873 | 1992 |
G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons C Lüscher, LY Jan, M Stoffel, RC Malenka, RA Nicoll Neuron 19 (3), 687-695, 1997 | 870 | 1997 |
A Family with Severe Insulin Resistance and Diabetes Due to a Mutation in AKT2 S George, JJ Rochford, C Wolfrum, SL Gray, S Schinner, JC Wilson, ... Science 304 (5675), 1325-1328, 2004 | 701 | 2004 |
Assessing the ceRNA hypothesis with quantitative measurements of miRNA and target abundance R Denzler, V Agarwal, J Stefano, DP Bartel, M Stoffel Molecular cell 54 (5), 766-776, 2014 | 658 | 2014 |
Specificity, duplex degradation and subcellular localization of antagomirs J Krützfeldt, S Kuwajima, R Braich, KG Rajeev, J Pena, T Tuschl, ... Nucleic acids research 35 (9), 2885-2892, 2007 | 614 | 2007 |
Whole population, genome-wide mapping of hidden relatedness A Gusev, JK Lowe, M Stoffel, MJ Daly, D Altshuler, JL Breslow, ... Genome research 19 (2), 318-326, 2009 | 536 | 2009 |
Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes C Wolfrum, E Asilmaz, E Luca, JM Friedman, M Stoffel Nature 432 (7020), 1027-1032, 2004 | 525 | 2004 |
The maturity-onset diabetes of the young (MODY1) transcription factor HNF4α regulates expression of genes required for glucose transport and metabolism M Stoffel, SA Duncan Proceedings of the National Academy of Sciences 94 (24), 13209-13214, 1997 | 517 | 1997 |
Hepatocyte nuclear factor-1α is an essential regulator of bile acid and plasma cholesterol metabolism DQ Shih, M Bussen, E Sehayek, M Ananthanarayanan, BL Shneider, ... Nature genetics 27 (4), 375-382, 2001 | 497 | 2001 |
MicroRNAs: a new class of regulatory genes affecting metabolism J Krützfeldt, M Stoffel Cell metabolism 4 (1), 9-12, 2006 | 453 | 2006 |
β-cell–specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter β-cell mass RN Kulkarni, M Holzenberger, DQ Shih, U Ozcan, M Stoffel, ... Nature genetics 31 (1), 111-115, 2002 | 448 | 2002 |