Recent progress in mucosal vaccine development: potential and limitations N Lycke Nature reviews immunology 12 (8), 592-605, 2012 | 809 | 2012 |
Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens. N Lycke, J Holmgren Immunology 59 (2), 301, 1986 | 532 | 1986 |
Cholera toxin and cholera B subunit as oral—mucosal adjuvant and antigen vector systems J Holmgren, N Lycke, C Czerkinsky Vaccine 11 (12), 1179-1184, 1993 | 429 | 1993 |
Murine CD4 T-cell response to Helicobacter infection: TH1 cells enhance gastritis and TH2 cells reduce bacterial load M Mohammadi, J Nedrud, R Redline, N Lycke, SJ Czinn Gastroenterology 113 (6), 1848-1857, 1997 | 365 | 1997 |
The adjuvant effect of Vibrio cholerae and Escherichia coli heat‐labile enterotoxins is linked to their ADP‐ribosyltransferase activity N Lycke, T Tsuji, J Holmgren European journal of immunology 22 (9), 2277-2281, 1992 | 331 | 1992 |
Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues C Czerkinsky, MW Russell, N Lycke, M Lindblad, J Holmgren Infection and immunity 57 (4), 1072-1077, 1989 | 316 | 1989 |
Isolation of mouse small intestinal intraepithelial lymphocytes, Peyer's patch, and lamina propria cells L Lefrançois, N Lycke Current protocols in immunology 17 (1), 3.19. 1-3.19. 16, 1996 | 288 | 1996 |
Mucosal immunity: implications for vaccine development J Holmgren, C Czerkinsky, N Lycke, AM Svennerholm Immunobiology 184 (2-3), 157-179, 1992 | 276 | 1992 |
Impaired mucosal immune responses in interleukin 4-targeted mice. M Vajdy, MH Kosco-Vilbois, M Kopf, G Köhler, N Lycke The Journal of experimental medicine 181 (1), 41-53, 1995 | 272 | 1995 |
Protection against Helicobacter pylori infection following immunization is IL-12-dependent and mediated by Th1 cells AA Akhiani, J Pappo, Z Kabok, K Schön, W Gao, LE Franzén, N Lycke The Journal of Immunology 169 (12), 6977-6984, 2002 | 267 | 2002 |
Genital tract infection with Chlamydia trachomatis fails to induce protective immunity in gamma interferon receptor-deficient mice despite a strong local immunoglobulin A response M Johansson, K Schön, M Ward, N Lycke Infection and immunity 65 (3), 1032-1044, 1997 | 261 | 1997 |
Cholera toxin stimulates IL-1 production and enhances antigen presentation by macrophages in vitro. A Bromander, J Holmgren, N Lycke Journal of immunology (Baltimore, Md.: 1950) 146 (9), 2908-2914, 1991 | 240 | 1991 |
Genetically engineered nontoxic vaccine adjuvant that combines B cell targeting with immunomodulation by cholera toxin A1 subunit. LC Agren, L Ekman, B Löwenadler, NY Lycke Journal of immunology (Baltimore, Md.: 1950) 158 (8), 3936-3946, 1997 | 238 | 1997 |
Gut IgA class switch recombination in the absence of CD40 does not occur in the lamina propria and is independent of germinal centers P Bergqvist, E Gärdby, A Stensson, M Bemark, NY Lycke The Journal of Immunology 177 (11), 7772-7783, 2006 | 197 | 2006 |
Improved design and intranasal delivery of an M2e-based human influenza A vaccine M De Filette, W Fiers, W Martens, A Birkett, A Ramne, B Löwenadler, ... Vaccine 24 (44-46), 6597-6601, 2006 | 197 | 2006 |
The regulation of gut mucosal IgA B-cell responses: recent developments NY Lycke, M Bemark Mucosal immunology 10 (6), 1361-1374, 2017 | 196 | 2017 |
The universal influenza vaccine M2e-HBc administered intranasally in combination with the adjuvant CTA1-DD provides complete protection M De Filette, A Ramne, A Birkett, N Lycke, B Löwenadler, WM Jou, ... Vaccine 24 (5), 544-551, 2006 | 176 | 2006 |
CTA1-M2e-DD: a novel mucosal adjuvant targeted influenza vaccine DG Eliasson, K El Bakkouri, K Schön, A Ramne, E Festjens, ... Vaccine 26 (9), 1243-1252, 2008 | 172 | 2008 |
Lack of J chain inhibits the transport of gut IgA and abrogates the development of intestinal antitoxic protection N Lycke, L Erlandsson, L Ekman, K Schön, T Leanderson The journal of immunology 163 (2), 913-919, 1999 | 158 | 1999 |
T cell-independent IgA class switch recombination is restricted to the GALT and occurs prior to manifest germinal center formation P Bergqvist, A Stensson, NY Lycke, M Bemark The Journal of Immunology 184 (7), 3545-3553, 2010 | 154 | 2010 |