Abnormal hyperphosphorylation of tau: sites, regulation, and molecular mechanism of neurofibrillary degeneration JZ Wang, YY Xia, I Grundke-Iqbal, K Iqbal Journal of Alzheimer's disease 33 (s1), S123-S139, 2013 | 608 | 2013 |
SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination HB Luo, YY Xia, XJ Shu, ZC Liu, Y Feng, XH Liu, G Yu, G Yin, YS Xiong, ... Proceedings of the National Academy of Sciences 111 (46), 16586-16591, 2014 | 206 | 2014 |
Gut microbiota regulate Alzheimer’s disease pathologies and cognitive disorders via PUFA-associated neuroinflammation C Chen, J Liao, Y Xia, X Liu, R Jones, J Haran, B McCormick, ... Gut 71 (11), 2233-2252, 2022 | 165 | 2022 |
Mitochondrial dysfunction in neural injury XY Zhao, MH Lu, DJ Yuan, DE Xu, PP Yao, WL Ji, H Chen, WL Liu, ... Frontiers in neuroscience 13, 30, 2019 | 105 | 2019 |
Cleavage of GSK‐3β by calpain counteracts the inhibitory effect of Ser9 phosphorylation on GSK‐3β activity induced by H2O2 Y Feng, Y Xia, G Yu, X Shu, H Ge, K Zeng, J Wang, X Wang Journal of neurochemistry 126 (2), 234-242, 2013 | 90 | 2013 |
Ginkgo biloba extract EGb761 attenuates hyperhomocysteinemia-induced AD like tau hyperphosphorylation and cognitive impairment in rats K Zeng, M Li, J Hu, YAR Mahaman, J Bao, F Huang, Y Xia, X Liu, Q Wang, ... Current Alzheimer Research 15 (1), 89-99, 2018 | 67 | 2018 |
Ser9 phosphorylation causes cytoplasmic detention of I2PP2A/SET in Alzheimer disease G Yu, T Yan, Y Feng, X Liu, Y Xia, H Luo, JZ Wang, X Wang Neurobiology of aging 34 (7), 1748-1758, 2013 | 66 | 2013 |
Codonopsis pilosula Polysaccharide Attenuates Tau Hyperphosphorylation and Cognitive Impairments in hTau Infected Mice Q Zhang, Y Xia, H Luo, S Huang, Y Wang, Y Shentu, YAR Mahaman, ... Frontiers in molecular neuroscience 11, 437, 2018 | 49 | 2018 |
BACE1 SUMOylation increases its stability and escalates the protease activity in Alzheimer’s disease J Bao, M Qin, YAR Mahaman, B Zhang, F Huang, K Zeng, Y Xia, D Ke, ... Proceedings of the National Academy of Sciences 115 (15), 3954-3959, 2018 | 38 | 2018 |
C/EBPβ is a key transcription factor for APOE and preferentially mediates ApoE4 expression in Alzheimer’s disease Y Xia, Z Wang, J Zhang, X Liu, SP Yu, KX Ye, JZ Wang, K Ye, XC Wang Molecular Psychiatry 26 (10), 6002-6022, 2021 | 36 | 2021 |
CK2 Phosphorylating I2PP2A/SET Mediates Tau Pathology and Cognitive Impairment Q Zhang, Y Xia, Y Wang, Y Shentu, K Zeng, YAR Mahaman, F Huang, ... Frontiers in Molecular Neuroscience 11, 146, 2018 | 34 | 2018 |
ApoE4 activates C/EBPβ/δ-secretase with 27-hydroxycholesterol, driving the pathogenesis of Alzheimer’s disease ZH Wang, Y Xia, P Liu, X Liu, L Edgington-Mitchell, K Lei, SP Yu, ... Progress in neurobiology 202, 102032, 2021 | 32 | 2021 |
Development of an α-synuclein positron emission tomography tracer for imaging synucleinopathies J Xiang, Y Tao, Y Xia, S Luo, Q Zhao, B Li, X Zhang, Y Sun, W Xia, ... Cell 186 (16), 3350-3367. e19, 2023 | 31 | 2023 |
ω-3PUFAs improve cognitive impairments through Ser133 phosphorylation of CREB upregulating BDNF/TrkB signal in schizophrenia C Guo, Y Liu, M Fang, Y Li, W Li, YAR Mahaman, K Zeng, Y Xia, D Ke, ... Neurotherapeutics 17 (3), 1271-1286, 2020 | 30 | 2020 |
C/EBPβ mediates NQO1 and GSTP1 anti-oxidative reductases expression in glioblastoma, promoting brain tumor proliferation K Lei, Y Xia, XC Wang, EH Ahn, L Jin, K Ye Redox biology 34, 101578, 2020 | 29 | 2020 |
Lamotrigine reduces β-site AβPP-cleaving enzyme 1 protein levels through induction of autophagy H Wu, MH Lu, W Wang, MY Zhang, QQ Zhu, YY Xia, RX Xu, Y Yang, ... Journal of Alzheimer's Disease 46 (4), 863-876, 2015 | 29 | 2015 |
C/EBPβ/δ-secretase signaling mediates Parkinson’s disease pathogenesis via regulating transcription and proteolytic cleavage of α-synuclein and MAOB Z Wu, Y Xia, Z Wang, S Su Kang, K Lei, X Liu, L Jin, X Wang, L Cheng, ... Molecular Psychiatry 26 (2), 568-585, 2021 | 28 | 2021 |
TrkB receptor cleavage by delta-secretase abolishes its phosphorylation of APP, aggravating Alzheimer’s disease pathologies Y Xia, ZH Wang, P Liu, L Edgington-Mitchell, X Liu, XC Wang, K Ye Molecular Psychiatry 26 (7), 2943-2963, 2021 | 26 | 2021 |
Netrin-1 receptor UNC5C cleavage by active δ-secretase enhances neurodegeneration, promoting Alzheimer’s disease pathologies G Chen, SS Kang, Z Wang, EH Ahn, Y Xia, X Liu, IM Sandoval, ... Science advances 7 (16), eabe4499, 2021 | 26 | 2021 |
High-fat diet-induced diabetes couples to Alzheimer’s disease through inflammation-activated C/EBPβ/AEP pathway P Liu, ZH Wang, SS Kang, X Liu, Y Xia, CB Chan, K Ye Molecular psychiatry 27 (8), 3396-3409, 2022 | 24 | 2022 |