| Characteristics of the novel potassium-competitive acid blocker vonoprazan fumarate (TAK-438) K Otake, Y Sakurai, H Nishida, H Fukui, Y Tagawa, H Yamasaki, ... Advances in therapy 33, 1140-1157, 2016 | 90 | 2016 |
| A novel solubilization technique for poorly soluble drugs through the integration of nanocrystal and cocrystal technologies M Karashima, K Kimoto, K Yamamoto, T Kojima, Y Ikeda European Journal of Pharmaceutics and Biopharmaceutics 107, 142-150, 2016 | 70 | 2016 |
| Enhanced pulmonary absorption of poorly soluble itraconazole by micronized cocrystal dry powder formulations M Karashima, N Sano, S Yamamoto, Y Arai, K Yamamoto, N Amano, ... European Journal of pharmaceutics and biopharmaceutics 115, 65-72, 2017 | 64 | 2017 |
| CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor T Funnell, S Tasaki, A Oloumi, S Araki, E Kong, D Yap, Y Nakayama, ... Nature Communications 8 (1), 7, 2017 | 57 | 2017 |
| Physicochemical evaluation and developability assessment of co-amorphouses of low soluble drugs and comparison to the co-crystals K Yamamoto, T Kojima, M Karashima, Y Ikeda Chemical and Pharmaceutical Bulletin 64 (12), 1739-1746, 2016 | 42 | 2016 |
| Effect of drug–polymer interactions through hypromellose acetate succinate substituents on the physical stability on solid dispersions studied by fourier-transform infrared and … Y Ishizuka, K Ueda, H Okada, J Takeda, M Karashima, K Yazawa, ... Molecular pharmaceutics 16 (6), 2785-2794, 2019 | 40 | 2019 |
| Pharmaceutical cocrystal development of TAK-020 with enhanced oral absorption K Kimoto, M Yamamoto, M Karashima, M Hohokabe, J Takeda, ... Crystals 10 (3), 211, 2020 | 29 | 2020 |
| Structural evaluation of the choline and geranic acid/water complex by SAXS and NMR analyses J Takeda, Y Iwao, M Karashima, K Yamamoto, Y Ikeda ACS Biomaterials Science & Engineering 7 (2), 595-604, 2021 | 25 | 2021 |
| Rational polymorph screening based on slow cooling crystallization of poorly soluble mebendazole M Karashima, K Kimoto, T Kojima, Y Ikeda Journal of crystal growth 390, 30-37, 2014 | 24 | 2014 |
| Prediction of human pharmacokinetic profile after transdermal drug application using excised human skin S Yamamoto, M Karashima, Y Arai, K Tohyama, N Amano Journal of Pharmaceutical Sciences 106 (9), 2787-2794, 2017 | 23 | 2017 |
| Combination of NMR methods to reveal the interfacial structure of a pharmaceutical nanocrystal and nanococrystal in the suspended state T Kojima, M Karashima, K Yamamoto, Y Ikeda Molecular Pharmaceutics 15 (9), 3901-3908, 2018 | 21 | 2018 |
| Discrimination and quantification of sulfathiazole polytypes using low-frequency Raman spectroscopy K Iwata, M Karashima, Y Ikeda, M Inoue, T Fukami CrystEngComm 20 (14), 1928-1934, 2018 | 17 | 2018 |
| Utility of Göttingen minipigs for prediction of human pharmacokinetic profiles after dermal drug application S Yamamoto, M Karashima, N Sano, C Fukushi, K Tohyama, Y Arai, ... Pharmaceutical Research 34, 2415-2424, 2017 | 14 | 2017 |
| Isotope-edited infrared spectroscopy for efficient discrimination between pharmaceutical salts and cocrystals K Iwata, M Karashima, Y Ikeda Molecular Pharmaceutics 14 (7), 2350-2358, 2017 | 13 | 2017 |
| Cocrystallization enhanced TAK-441 aqueous solubility and suppressed high solvatomorphism K Iwata, M Karashima, Y Ikeda Crystal Growth & Design 16 (8), 4599-4606, 2016 | 11 | 2016 |
| Pinpoint modification strategy for stabilization of single guide RNA YI S.Takeuchi, M.Yamamoto, S.Matsumoto, E.Kenjo, M.Karashima J. Chromatogr. B 1192 (123149), 2022 | 5 | 2022 |
| Development of a chemically assisted micro-beam etching system for three-dimensional microanalysis Y Tanaka, M Karashima, K Takanashi, T Sakamoto, M Owari, Y Nihei Applied surface science 203, 205-208, 2003 | 5 | 2003 |
| Nanostructure and molecular-level characterization of aminoalkyl methacrylate copolymer and the impact on drug solubilization ability Y Okamoto, K Higashi, T Morita, K Ueda, S Mukaide, J Takeda, ... Molecular Pharmaceutics 18 (11), 4111-4121, 2021 | 2 | 2021 |
| Utility of hairless rats as a model for predicting transdermal pharmacokinetics in humans S Yamamoto, N Sano, C Fukushi, Y Arai, M Karashima, H Hirabayashi, ... Xenobiotica 50 (7), 831-838, 2020 | 1 | 2020 |
| Suspension containing nano-cocrystal and manufacturing method M Karashima, K Yamamoto, T Kojima, Y Ikeda US Patent 10,226,426, 2019 | 1 | 2019 |
