Microenvironmental regulation of therapeutic response in cancer F Klemm, JA Joyce Trends in cell biology 25 (4), 198-213, 2015 | 764 | 2015 |
Interrogation of the microenvironmental landscape in brain tumors reveals disease-specific alterations of immune cells F Klemm, RR Maas, RL Bowman, M Kornete, K Soukup, S Nassiri, ... Cell 181 (7), 1643-1660. e17, 2020 | 652 | 2020 |
Macrophages induce invasiveness of epithelial cancer cells via NF-κB and JNK T Hagemann, J Wilson, H Kulbe, NF Li, DA Leinster, K Charles, F Klemm, ... The Journal of Immunology 175 (2), 1197-1205, 2005 | 590 | 2005 |
Macrophage ontogeny underlies differences in tumor-specific education in brain malignancies RL Bowman, F Klemm, L Akkari, SM Pyonteck, L Sevenich, DF Quail, ... Cell reports 17 (9), 2445-2459, 2016 | 548 | 2016 |
Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines T Pukrop, F Klemm, T Hagemann, D Gradl, M Schulz, S Siemes, ... Proceedings of the National Academy of Sciences 103 (14), 5454-5459, 2006 | 433 | 2006 |
Microglia promote colonization of brain tissue by breast cancer cells in a Wnt‐dependent way T Pukrop, F Dehghani, HN Chuang, R Lohaus, K Bayanga, S Heermann, ... Glia 58 (12), 1477-1489, 2010 | 236 | 2010 |
Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance L Akkari, RL Bowman, J Tessier, F Klemm, SM Handgraaf, M de Groot, ... Science translational medicine 12 (552), eaaw7843, 2020 | 214 | 2020 |
Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN K Menck, C Scharf, A Bleckmann, L Dyck, U Rost, D Wenzel, VM Dhople, ... Journal of molecular cell biology 7 (2), 143-153, 2015 | 156 | 2015 |
β-catenin-independent WNT signaling in basal-like breast cancer and brain metastasis F Klemm, A Bleckmann, L Siam, HN Chuang, E Rietkoetter, D Behme, ... Carcinogenesis 32 (3), 434-442, 2011 | 150 | 2011 |
Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles K Menck, F Klemm, JC Gross, T Pukrop, D Wenzel, C Binder Oncotarget 4 (11), 2057, 2013 | 139 | 2013 |
Isolation of human monocytes by double gradient centrifugation and their differentiation to macrophages in teflon-coated cell culture bags K Menck, D Behme, M Pantke, N Reiling, C Binder, T Pukrop, F Klemm JoVE (Journal of Visualized Experiments), e51554, 2014 | 121 | 2014 |
The metastatic infiltration at the metastasis/brain parenchyma-interface is very heterogeneous and has a significant impact on survival in a prospective study L Siam, A Bleckmann, HN Chaung, A Mohr, F Klemm, A Barrantes-Freer, ... Oncotarget 6 (30), 29254, 2015 | 96 | 2015 |
Characterisation of tumour-derived microvesicles in cancer patients’ blood and correlation with clinical outcome K Menck, A Bleckmann, A Wachter, B Hennies, L Ries, M Schulz, ... Journal of Extracellular Vesicles 6 (1), 1340745, 2017 | 93 | 2017 |
Comparative study on gene set and pathway topology-based enrichment methods M Bayerlová, K Jung, F Kramer, F Klemm, A Bleckmann, T Beißbarth BMC bioinformatics 16, 1-15, 2015 | 78 | 2015 |
Carcinoma cells misuse the host tissue damage response to invade the brain HN Chuang, D van Rossum, D Sieger, L Siam, F Klemm, A Bleckmann, ... Glia 61 (8), 1331-1346, 2013 | 77 | 2013 |
Nuclear LEF1/TCF4 correlate with poor prognosis but not with nuclear β-catenin in cerebral metastasis of lung adenocarcinomas A Bleckmann, L Siam, F Klemm, E Rietkoetter, C Wegner, F Kramer, ... Clinical & experimental metastasis 30, 471-482, 2013 | 54 | 2013 |
Ror2 signaling and its relevance in breast cancer progression M Bayerlová, K Menck, F Klemm, A Wolff, T Pukrop, C Binder, T Beißbarth, ... Frontiers in oncology 7, 135, 2017 | 53 | 2017 |
Compensatory CSF2-driven macrophage activation promotes adaptive resistance to CSF1R inhibition in breast-to-brain metastasis F Klemm, A Möckl, A Salamero-Boix, T Alekseeva, A Schäffer, M Schulz, ... Nature cancer 2 (10), 1086-1101, 2021 | 52 | 2021 |
β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases A Bleckmann, LC Conradi, K Menck, NA Schmick, A Schubert, ... Clinical & experimental metastasis 33, 309-323, 2016 | 46 | 2016 |
rBiopaxParser—an R package to parse, modify and visualize BioPAX data F Kramer, M Bayerlova, F Klemm, A Bleckmann, T Beißbarth Bioinformatics 29 (4), 520-522, 2013 | 44 | 2013 |