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Florian Klemm
Florian Klemm
University of Lausanne, Department of Oncology, Ludwig Institute for Cancer Research
在 unil.ch 的电子邮件经过验证
标题
引用次数
引用次数
年份
Microenvironmental regulation of therapeutic response in cancer
F Klemm, JA Joyce
Trends in cell biology 25 (4), 198-213, 2015
7642015
Interrogation of the microenvironmental landscape in brain tumors reveals disease-specific alterations of immune cells
F Klemm, RR Maas, RL Bowman, M Kornete, K Soukup, S Nassiri, ...
Cell 181 (7), 1643-1660. e17, 2020
6522020
Macrophages induce invasiveness of epithelial cancer cells via NF-κB and JNK
T Hagemann, J Wilson, H Kulbe, NF Li, DA Leinster, K Charles, F Klemm, ...
The Journal of Immunology 175 (2), 1197-1205, 2005
5902005
Macrophage ontogeny underlies differences in tumor-specific education in brain malignancies
RL Bowman, F Klemm, L Akkari, SM Pyonteck, L Sevenich, DF Quail, ...
Cell reports 17 (9), 2445-2459, 2016
5482016
Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines
T Pukrop, F Klemm, T Hagemann, D Gradl, M Schulz, S Siemes, ...
Proceedings of the National Academy of Sciences 103 (14), 5454-5459, 2006
4332006
Microglia promote colonization of brain tissue by breast cancer cells in a Wnt‐dependent way
T Pukrop, F Dehghani, HN Chuang, R Lohaus, K Bayanga, S Heermann, ...
Glia 58 (12), 1477-1489, 2010
2362010
Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance
L Akkari, RL Bowman, J Tessier, F Klemm, SM Handgraaf, M de Groot, ...
Science translational medicine 12 (552), eaaw7843, 2020
2142020
Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN
K Menck, C Scharf, A Bleckmann, L Dyck, U Rost, D Wenzel, VM Dhople, ...
Journal of molecular cell biology 7 (2), 143-153, 2015
1562015
β-catenin-independent WNT signaling in basal-like breast cancer and brain metastasis
F Klemm, A Bleckmann, L Siam, HN Chuang, E Rietkoetter, D Behme, ...
Carcinogenesis 32 (3), 434-442, 2011
1502011
Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles
K Menck, F Klemm, JC Gross, T Pukrop, D Wenzel, C Binder
Oncotarget 4 (11), 2057, 2013
1392013
Isolation of human monocytes by double gradient centrifugation and their differentiation to macrophages in teflon-coated cell culture bags
K Menck, D Behme, M Pantke, N Reiling, C Binder, T Pukrop, F Klemm
JoVE (Journal of Visualized Experiments), e51554, 2014
1212014
The metastatic infiltration at the metastasis/brain parenchyma-interface is very heterogeneous and has a significant impact on survival in a prospective study
L Siam, A Bleckmann, HN Chaung, A Mohr, F Klemm, A Barrantes-Freer, ...
Oncotarget 6 (30), 29254, 2015
962015
Characterisation of tumour-derived microvesicles in cancer patients’ blood and correlation with clinical outcome
K Menck, A Bleckmann, A Wachter, B Hennies, L Ries, M Schulz, ...
Journal of Extracellular Vesicles 6 (1), 1340745, 2017
932017
Comparative study on gene set and pathway topology-based enrichment methods
M Bayerlová, K Jung, F Kramer, F Klemm, A Bleckmann, T Beißbarth
BMC bioinformatics 16, 1-15, 2015
782015
Carcinoma cells misuse the host tissue damage response to invade the brain
HN Chuang, D van Rossum, D Sieger, L Siam, F Klemm, A Bleckmann, ...
Glia 61 (8), 1331-1346, 2013
772013
Nuclear LEF1/TCF4 correlate with poor prognosis but not with nuclear β-catenin in cerebral metastasis of lung adenocarcinomas
A Bleckmann, L Siam, F Klemm, E Rietkoetter, C Wegner, F Kramer, ...
Clinical & experimental metastasis 30, 471-482, 2013
542013
Ror2 signaling and its relevance in breast cancer progression
M Bayerlová, K Menck, F Klemm, A Wolff, T Pukrop, C Binder, T Beißbarth, ...
Frontiers in oncology 7, 135, 2017
532017
Compensatory CSF2-driven macrophage activation promotes adaptive resistance to CSF1R inhibition in breast-to-brain metastasis
F Klemm, A Möckl, A Salamero-Boix, T Alekseeva, A Schäffer, M Schulz, ...
Nature cancer 2 (10), 1086-1101, 2021
522021
β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases
A Bleckmann, LC Conradi, K Menck, NA Schmick, A Schubert, ...
Clinical & experimental metastasis 33, 309-323, 2016
462016
rBiopaxParser—an R package to parse, modify and visualize BioPAX data
F Kramer, M Bayerlova, F Klemm, A Bleckmann, T Beißbarth
Bioinformatics 29 (4), 520-522, 2013
442013
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