| Structural basis for dual-mode inhibition of the ABC transporter MsbA H Ho, A Miu, MK Alexander, NK Garcia, A Oh, I Zilberleyb, M Reichelt, ... Nature 557 (7704), 196-201, 2018 | 156 | 2018 |
| Toward better refinement of comparative models: predicting loops in inexact environments BD Sellers, K Zhu, S Zhao, RA Friesner, MP Jacobson Proteins: Structure, Function, and Bioinformatics 72 (3), 959-971, 2008 | 101 | 2008 |
| Discovery of GluN2A-selective NMDA receptor positive allosteric modulators (PAMs): tuning deactivation kinetics via structure-based design M Volgraf, BD Sellers, Y Jiang, G Wu, CQ Ly, E Villemure, RM Pastor, ... Journal of medicinal chemistry 59 (6), 2760-2779, 2016 | 97 | 2016 |
| Conformation switching of clathrin light chain regulates clathrin lattice assembly JD Wilbur, PK Hwang, JA Ybe, M Lane, BD Sellers, MP Jacobson, ... Developmental cell 18 (5), 854-861, 2010 | 89 | 2010 |
| Structure of the essential inner membrane lipopolysaccharide–PbgA complex T Clairfeuille, KR Buchholz, Q Li, E Verschueren, P Liu, D Sangaraju, ... Nature 584 (7821), 479-483, 2020 | 76 | 2020 |
| A comparison of quantum and molecular mechanical methods to estimate strain energy in druglike fragments BD Sellers, NC James, A Gobbi Journal of chemical information and modeling 57 (6), 1265-1275, 2017 | 70 | 2017 |
| GluN2A NMDA receptor enhancement improves brain oscillations, synchrony, and cognitive functions in Dravet syndrome and Alzheimer’s disease models JE Hanson, K Ma, J Elstrott, M Weber, S Saillet, AS Khan, J Simms, B Liu, ... Cell reports 30 (2), 381-396. e4, 2020 | 68 | 2020 |
| Disrupting gram-negative bacterial outer membrane biosynthesis through inhibition of the lipopolysaccharide transporter MsbA MK Alexander, A Miu, A Oh, M Reichelt, H Ho, C Chalouni, S Labadie, ... Antimicrobial Agents and Chemotherapy 62 (11), 10.1128/aac. 01142-18, 2018 | 63 | 2018 |
| Energy-based analysis and prediction of the orientation between light-and heavy-chain antibody variable domains A Narayanan, BD Sellers, MP Jacobson Journal of molecular biology 388 (5), 941-953, 2009 | 56 | 2009 |
| Improving the species cross-reactivity of an antibody using computational design CJ Farady, BD Sellers, MP Jacobson, CS Craik Bioorganic & medicinal chemistry letters 19 (14), 3744-3747, 2009 | 55 | 2009 |
| Effects of somatic mutations on CDR loop flexibility during affinity maturation SE Wong, BD Sellers, MP Jacobson Proteins: Structure, Function, and Bioinformatics 79 (3), 821-829, 2011 | 51 | 2011 |
| Intelligent drawing redlining and commenting feature VJ Abeyta, DM Hallbauer, LD Horner, JA Natarajan, BD Sellers US Patent 6,628,285, 2003 | 42 | 2003 |
| Towards an improved understanding of drug excipient interactions to enable rapid optimization of nanosuspension formulations JA Ferrar, BD Sellers, C Chan, DH Leung International Journal of Pharmaceutics 578, 119094, 2020 | 38 | 2020 |
| Aminoisoxazoles as potent inhibitors of tryptophan 2, 3-dioxygenase 2 (TDO2) Z Pei, R Mendonca, L Gazzard, R Pastor, L Goon, A Gustafson, ... ACS medicinal chemistry letters 9 (5), 417-421, 2018 | 37 | 2018 |
| GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile E Villemure, M Volgraf, Y Jiang, G Wu, CQ Ly, P Yuen, A Lu, X Luo, M Liu, ... ACS Medicinal Chemistry Letters 8 (1), 84-89, 2017 | 37 | 2017 |
| A novel NMDA receptor positive allosteric modulator that acts via the transmembrane domain TM Wang, BM Brown, L Deng, BD Sellers, PJ Lupardus, HJA Wallweber, ... Neuropharmacology 121, 204-218, 2017 | 31 | 2017 |
| Identification of Selective Acyl Sulfonamide–Cycloalkylether Inhibitors of the Voltage-Gated Sodium Channel (NaV) 1.7 with Potent Analgesic Activity S Sun, Q Jia, AY Zenova, MS Wilson, S Chowdhury, T Focken, J Li, ... Journal of medicinal chemistry 62 (2), 908-927, 2018 | 30 | 2018 |
| Computationally discovered potentiating role of glycans on NMDA receptors AV Sinitskiy, NH Stanley, DH Hackos, JE Hanson, BD Sellers, VS Pande Scientific Reports 7 (1), 44578, 2017 | 30 | 2017 |
| Implementation of the CYP Index for the Design of Selective Tryptophan-2, 3-dioxygenase Inhibitors BT Parr, R Pastor, BD Sellers, Z Pei, FA Jaipuri, GM Castanedo, ... ACS Medicinal Chemistry Letters 11 (4), 541-549, 2020 | 23 | 2020 |
| Antibodies as a model system for comparative model refinement BD Sellers, JP Nilmeier, MP Jacobson Proteins: Structure, Function, and Bioinformatics 78 (11), 2490-2505, 2010 | 22 | 2010 |
