Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system J Bondy-Denomy, A Pawluk, KL Maxwell, AR Davidson Nature 493 (7432), 429-432, 2013 | 926 | 2013 |
Naturally occurring off-switches for CRISPR-Cas9 A Pawluk, N Amrani, Y Zhang, B Garcia, Y Hidalgo-Reyes, J Lee, A Edraki, ... Cell 167 (7), 1829-1838. e9, 2016 | 424 | 2016 |
Anti-CRISPR: discovery, mechanism and function A Pawluk, AR Davidson, KL Maxwell Nature Reviews Microbiology 16 (1), 12-17, 2018 | 387 | 2018 |
Inactivation of CRISPR-Cas systems by anti-CRISPR proteins in diverse bacterial species A Pawluk, RHJ Staals, C Taylor, BNJ Watson, S Saha, PC Fineran, ... Nature microbiology 1 (8), 1-6, 2016 | 351 | 2016 |
A new group of phage anti-CRISPR genes inhibits the type IE CRISPR-Cas system of Pseudomonas aeruginosa A Pawluk, J Bondy-Denomy, VHW Cheung, KL Maxwell, AR Davidson MBio 5 (2), 10.1128/mbio. 00896-14, 2014 | 292 | 2014 |
Disabling a type IE CRISPR-Cas nuclease with a bacteriophage-encoded anti-CRISPR protein A Pawluk, M Shah, M Mejdani, C Calmettes, TF Moraes, AR Davidson, ... MBio 8 (6), 10.1128/mbio. 01751-17, 2017 | 95 | 2017 |
Potent Cas9 inhibition in bacterial and human cells by AcrIIC4 and AcrIIC5 anti-CRISPR proteins J Lee, A Mir, A Edraki, B Garcia, N Amrani, HE Lou, I Gainetdinov, ... MBio 9 (6), 10.1128/mbio. 02321-18, 2018 | 94 | 2018 |
Discovery of bioactive microbial gene products in inflammatory bowel disease Y Zhang, A Bhosle, S Bae, LJ McIver, G Pishchany, EK Accorsi, ... Nature 606 (7915), 754-760, 2022 | 47 | 2022 |
Deep learning and CRISPR-Cas13d ortholog discovery for optimized RNA targeting J Wei, P Lotfy, K Faizi, S Baungaard, E Gibson, E Wang, H Slabodkin, ... Cell Systems 14 (12), 1087-1102. e13, 2023 | 23 | 2023 |
Anti-CRISPR AcrIE2 binds the type IE CRISPR-Cas complex but does not block DNA binding M Mejdani, A Pawluk, KL Maxwell, AR Davidson Journal of Molecular Biology 433 (3), 166759, 2021 | 14 | 2021 |
Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes KN Thompson, KS Bonham, NE Ilott, GJ Britton, P Colmenero, SJ Bullers, ... Science translational medicine 15 (706), eabn4722, 2023 | 11 | 2023 |
Disabling a type IE CRISPR-Cas nuclease with a bacteriophage-encoded anti-CRISPR protein. mBio 8: e01751-17 A Pawluk, M Shah, M Mejdani, C Calmettes, TF Moraes, AR Davidson, ... | 7 | 2017 |
Tiny answers to big questions A Pawluk Cell 170 (2), 217, 2017 | 5 | 2017 |
CRISPR: no sign of slowing down A Pawluk Cell 174 (5), 1039, 2018 | 4 | 2018 |
Structural mechanism of bridge RNA-guided recombination M Hiraizumi, NT Perry, MG Durrant, T Soma, N Nagahata, S Okazaki, ... Nature 630 (8018), 994-1002, 2024 | 3 | 2024 |
Bridge RNAs direct programmable recombination of target and donor DNA MG Durrant, NT Perry, JJ Pai, AR Jangid, JS Athukoralage, M Hiraizumi, ... Nature 630 (8018), 984-993, 2024 | 2 | 2024 |
Bridge RNAs direct modular and programmable recombination of target and donor DNA MG Durrant, NT Perry, JJ Pai, AR Jangid, JS Athukoralage, M Hiraizumi, ... bioRxiv, 2024 | 1 | 2024 |
Breaking the Rules A Pawluk Cell 173 (4), 807, 2018 | 1 | 2018 |
Prevalence, Diversity, Impact, and Applications of CRISPR-Cas Inhibitors AIE Pawluk University of Toronto (Canada), 2016 | 1 | 2016 |
Rewriting endogenous human transcripts with trans-splicing SS Chandrasekaran, C Tau, M Nemeth, A Pawluk, S Konermann, PD Hsu bioRxiv, 2024.01. 29.577779, 2024 | | 2024 |