Efficient evolution of human antibodies from general protein language models BL Hie, VR Shanker, D Xu, TUJ Bruun, PA Weidenbacher, S Tang, W Wu, ... Nature Biotechnology 42 (2), 275-283, 2024 | 260 | 2024 |
Engineering a rugged nanoscaffold to enhance plug-and-display vaccination TUJ Bruun, AMC Andersson, SJ Draper, M Howarth ACS nano 12 (9), 8855-8866, 2018 | 251 | 2018 |
A New Multicomponent Multicatalyst Reaction (MC)2R: Chemoselective Cycloaddition and Latent Catalyst Activation for the Synthesis of Fully Substituted 1,2,3 … K Yamamoto, T Bruun, JY Kim, L Zhang, M Lautens Organic letters 18 (11), 2644-2647, 2016 | 86 | 2016 |
Phenotypic and genotypic spectrum of congenital disorders of glycosylation type I and type II A Al Teneiji, TUJ Bruun, S Sidky, D Cordeiro, RD Cohn, ... Molecular genetics and metabolism 120 (3), 235-242, 2017 | 70 | 2017 |
Phenotype, biochemical features, genotype and treatment outcome of pyridoxine-dependent epilepsy A Al Teneiji, TUJ Bruun, D Cordeiro, J Patel, M Inbar-Feigenberg, S Weiss, ... Metabolic brain disease 32, 443-451, 2017 | 65 | 2017 |
Cu/Pd-Catalyzed Synthesis of Fully Decorated Polycyclic Triazoles: Introducing C–H Functionalization to Multicomponent Multicatalytic Reactions ((MC)2R) Z Qureshi, JY Kim, T Bruun, H Lam, M Lautens ACS Catalysis 6 (8), 4946-4952, 2016 | 65 | 2016 |
Prospective cohort study for identification of underlying genetic causes in neonatal encephalopathy using whole-exome sequencing TUJ Bruun, CL DesRoches, D Wilson, V Chau, T Nakagawa, M Yamasaki, ... Genetics in Medicine 20 (5), 486-494, 2018 | 61 | 2018 |
Treatment outcome of creatine transporter deficiency: international retrospective cohort study TUJ Bruun, S Sidky, AO Bandeira, FG Debray, C Ficicioglu, J Goldstein, ... Metabolic brain disease 33, 875-884, 2018 | 43 | 2018 |
Unsupervised evolution of protein and antibody complexes with a structure-informed language model VR Shanker, TUJ Bruun, BL Hie, PS Kim Science 385 (6704), 46-53, 2024 | 22 | 2024 |
Broad and Durable Humoral Responses Following Single Hydrogel Immunization of SARS‐CoV‐2 Subunit Vaccine BS Ou, OM Saouaf, J Yan, TUJ Bruun, J Baillet, X Zhou, NP King, ... Advanced Healthcare Materials 12 (28), 2301495, 2023 | 14 | 2023 |
Inverse folding of protein complexes with a structure-informed language model enables unsupervised antibody evolution VR Shanker, TUJ Bruun, BL Hie, PS Kim bioRxiv, 2023 | 13 | 2023 |
A derivative of the D5 monoclonal antibody that targets the gp41 N-heptad repeat of HIV-1 with broad tier-2-neutralizing activity AA Rubio, MV Filsinger Interrante, BN Bell, CL Brown, TUJ Bruun, ... Journal of Virology 95 (15), 10.1128/jvi. 02350-20, 2021 | 12 | 2021 |
Chemoselective Organoclick–Click Sequence M Belkheira, D El Abed, JM Pons, C Bressy Synthesis 50 (21), 4254-4262, 2018 | 10 | 2018 |
Arginine–Glycine Amidinotransferase Deficiency and Functional Characterization of Missense Variants in GATM CL DesRoches, T Bruun, P Wang, CR Marshall, S Mercimek‐Mahmutoglu Human Mutation 37 (9), 926-932, 2016 | 8 | 2016 |
A structural blueprint for interleukin-21 signal modulation GC Abhiraman, TUJ Bruun, NA Caveney, LL Su, RA Saxton, Q Yin, ... Cell Reports 42 (6), 2023 | 3 | 2023 |
Structure-guided stabilization improves the ability of the HIV-1 gp41 hydrophobic pocket to elicit neutralizing antibodies TUJ Bruun, S Tang, G Erwin, L Deis, D Fernandez, PS Kim Journal of Biological Chemistry 299 (4), 2023 | 3 | 2023 |
HIV-1 prehairpin intermediate inhibitors show efficacy independent of neutralization tier BN Bell, TUJ Bruun, N Friedland, PS Kim Proceedings of the National Academy of Sciences 120 (8), e2215792120, 2023 | 2* | 2023 |
Stereoselective Synthesis of d4-(S)-Lysine from (S)-Serine M Kohr, U Kazmaier Synthesis 50 (23), 4690-4694, 2018 | 1 | 2018 |
Engineering a SARS-CoV-2 Vaccine Targeting the Receptor-Binding Domain Cryptic-Face via Immunofocusing TUJ Bruun, J Do, PAB Weidenbacher, A Utz, PS Kim ACS Central Science 10 (10), 1871-1884, 2024 | | 2024 |
Engineering a SARS-CoV-2 vaccine targeting the RBD cryptic-face via immunofocusing TUJ Bruun, J Do, PAB Weidenbacher, PS Kim bioRxiv, 2024 | | 2024 |