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Theodora Bruun
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Efficient evolution of human antibodies from general protein language models
BL Hie, VR Shanker, D Xu, TUJ Bruun, PA Weidenbacher, S Tang, W Wu, ...
Nature Biotechnology 42 (2), 275-283, 2024
2602024
Engineering a rugged nanoscaffold to enhance plug-and-display vaccination
TUJ Bruun, AMC Andersson, SJ Draper, M Howarth
ACS nano 12 (9), 8855-8866, 2018
2512018
A New Multicomponent Multicatalyst Reaction (MC)2R: Chemoselective Cycloaddition and Latent Catalyst Activation for the Synthesis of Fully Substituted 1,2,3 …
K Yamamoto, T Bruun, JY Kim, L Zhang, M Lautens
Organic letters 18 (11), 2644-2647, 2016
862016
Phenotypic and genotypic spectrum of congenital disorders of glycosylation type I and type II
A Al Teneiji, TUJ Bruun, S Sidky, D Cordeiro, RD Cohn, ...
Molecular genetics and metabolism 120 (3), 235-242, 2017
702017
Phenotype, biochemical features, genotype and treatment outcome of pyridoxine-dependent epilepsy
A Al Teneiji, TUJ Bruun, D Cordeiro, J Patel, M Inbar-Feigenberg, S Weiss, ...
Metabolic brain disease 32, 443-451, 2017
652017
Cu/Pd-Catalyzed Synthesis of Fully Decorated Polycyclic Triazoles: Introducing C–H Functionalization to Multicomponent Multicatalytic Reactions ((MC)2R)
Z Qureshi, JY Kim, T Bruun, H Lam, M Lautens
ACS Catalysis 6 (8), 4946-4952, 2016
652016
Prospective cohort study for identification of underlying genetic causes in neonatal encephalopathy using whole-exome sequencing
TUJ Bruun, CL DesRoches, D Wilson, V Chau, T Nakagawa, M Yamasaki, ...
Genetics in Medicine 20 (5), 486-494, 2018
612018
Treatment outcome of creatine transporter deficiency: international retrospective cohort study
TUJ Bruun, S Sidky, AO Bandeira, FG Debray, C Ficicioglu, J Goldstein, ...
Metabolic brain disease 33, 875-884, 2018
432018
Unsupervised evolution of protein and antibody complexes with a structure-informed language model
VR Shanker, TUJ Bruun, BL Hie, PS Kim
Science 385 (6704), 46-53, 2024
222024
Broad and Durable Humoral Responses Following Single Hydrogel Immunization of SARS‐CoV‐2 Subunit Vaccine
BS Ou, OM Saouaf, J Yan, TUJ Bruun, J Baillet, X Zhou, NP King, ...
Advanced Healthcare Materials 12 (28), 2301495, 2023
142023
Inverse folding of protein complexes with a structure-informed language model enables unsupervised antibody evolution
VR Shanker, TUJ Bruun, BL Hie, PS Kim
bioRxiv, 2023
132023
A derivative of the D5 monoclonal antibody that targets the gp41 N-heptad repeat of HIV-1 with broad tier-2-neutralizing activity
AA Rubio, MV Filsinger Interrante, BN Bell, CL Brown, TUJ Bruun, ...
Journal of Virology 95 (15), 10.1128/jvi. 02350-20, 2021
122021
Chemoselective Organoclick–Click Sequence
M Belkheira, D El Abed, JM Pons, C Bressy
Synthesis 50 (21), 4254-4262, 2018
102018
Arginine–Glycine Amidinotransferase Deficiency and Functional Characterization of Missense Variants in GATM
CL DesRoches, T Bruun, P Wang, CR Marshall, S Mercimek‐Mahmutoglu
Human Mutation 37 (9), 926-932, 2016
82016
A structural blueprint for interleukin-21 signal modulation
GC Abhiraman, TUJ Bruun, NA Caveney, LL Su, RA Saxton, Q Yin, ...
Cell Reports 42 (6), 2023
32023
Structure-guided stabilization improves the ability of the HIV-1 gp41 hydrophobic pocket to elicit neutralizing antibodies
TUJ Bruun, S Tang, G Erwin, L Deis, D Fernandez, PS Kim
Journal of Biological Chemistry 299 (4), 2023
32023
HIV-1 prehairpin intermediate inhibitors show efficacy independent of neutralization tier
BN Bell, TUJ Bruun, N Friedland, PS Kim
Proceedings of the National Academy of Sciences 120 (8), e2215792120, 2023
2*2023
Stereoselective Synthesis of d4-(S)-Lysine from (S)-Serine
M Kohr, U Kazmaier
Synthesis 50 (23), 4690-4694, 2018
12018
Engineering a SARS-CoV-2 Vaccine Targeting the Receptor-Binding Domain Cryptic-Face via Immunofocusing
TUJ Bruun, J Do, PAB Weidenbacher, A Utz, PS Kim
ACS Central Science 10 (10), 1871-1884, 2024
2024
Engineering a SARS-CoV-2 vaccine targeting the RBD cryptic-face via immunofocusing
TUJ Bruun, J Do, PAB Weidenbacher, PS Kim
bioRxiv, 2024
2024
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