ROS function in redox signaling and oxidative stress M Schieber, NS Chandel Current biology 24 (10), R453-R462, 2014 | 5051 | 2014 |
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 3815 | 2018 |
Physiological roles of mitochondrial reactive oxygen species LA Sena, NS Chandel Molecular cell 48 (2), 158-167, 2012 | 2482 | 2012 |
Mitochondrial reactive oxygen species trigger hypoxia-induced transcription NS Chandel, E Maltepe, E Goldwasser, CE Mathieu, MC Simon, ... Proceedings of the National Academy of Sciences 95 (20), 11715-11720, 1998 | 2241 | 1998 |
Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1α during hypoxia: a mechanism of O2 sensing NS Chandel, DS McClintock, CE Feliciano, TM Wood, JA Melendez, ... Journal of Biological Chemistry 275 (33), 25130-25138, 2000 | 2214 | 2000 |
Fundamentals of cancer metabolism RJ DeBerardinis, NS Chandel Science advances 2 (5), e1600200, 2016 | 2125 | 2016 |
Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria MG Vander Heiden, NS Chandel, EK Williamson, PT Schumacker, ... Cell 91 (5), 627-637, 1997 | 1711 | 1997 |
Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity F Weinberg, R Hamanaka, WW Wheaton, S Weinberg, J Joseph, M Lopez, ... Proceedings of the National Academy of Sciences 107 (19), 8788-8793, 2010 | 1593 | 2010 |
Reductive carboxylation supports growth in tumour cells with defective mitochondria AR Mullen, WW Wheaton, ES Jin, PH Chen, LB Sullivan, T Cheng, ... Nature 481 (7381), 385-388, 2012 | 1265 | 2012 |
Targeting mitochondria metabolism for cancer therapy SE Weinberg, NS Chandel Nature chemical biology 11 (1), 9-15, 2015 | 1155 | 2015 |
AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress SM Jeon, NS Chandel, N Hay Nature 485 (7400), 661-665, 2012 | 1064 | 2012 |
Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling LA Sena, S Li, A Jairaman, M Prakriya, T Ezponda, DA Hildeman, ... Immunity 38 (2), 225-236, 2013 | 1038 | 2013 |
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 L Galluzzi, BS Pedro, I Vitale, SA Aaronson, JM Abrams, D Adam, ... Cell Death & Differentiation 22 (1), 58-73, 2015 | 1009 | 2015 |
Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes RB Hamanaka, NS Chandel Trends in biochemical sciences 35 (9), 505-513, 2010 | 1000 | 2010 |
Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis WW Wheaton, SE Weinberg, RB Hamanaka, S Soberanes, LB Sullivan, ... elife 3, e02242, 2014 | 949 | 2014 |
Mitochondrial TCA cycle metabolites control physiology and disease I Martínez-Reyes, NS Chandel Nature communications 11 (1), 102, 2020 | 937 | 2020 |
Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation JK Brunelle, EL Bell, NM Quesada, K Vercauteren, V Tiranti, M Zeviani, ... Cell metabolism 1 (6), 409-414, 2005 | 849 | 2005 |
ROS-dependent signal transduction CR Reczek, NS Chandel Current opinion in cell biology 33, 8-13, 2015 | 803 | 2015 |
Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes J Duranteau, NS Chandel, A Kulisz, Z Shao, PT Schumacker Journal of biological chemistry 273 (19), 11619-11624, 1998 | 789 | 1998 |
Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak N Majewski, V Nogueira, P Bhaskar, PE Coy, JE Skeen, K Gottlob, ... Molecular cell 16 (5), 819-830, 2004 | 740 | 2004 |