| Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression CA Brady, D Jiang, SS Mello, TM Johnson, LA Jarvis, MM Kozak, DK Broz, ... Cell 145 (4), 571-583, 2011 | 600 | 2011 |
| Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses DK Broz, SS Mello, KT Bieging, D Jiang, RL Dusek, CA Brady, A Sidow, ... Genes & development 27 (9), 1016-1031, 2013 | 456 | 2013 |
| Targeting the IRE1α–XBP1 branch of the unfolded protein response in human diseases D Jiang, M Niwa, AC Koong Seminars in cancer biology 33, 48-56, 2015 | 200 | 2015 |
| Reprogramming the immunological microenvironment through radiation and targeting Axl TA Aguilera, M Rafat, L Castellini, H Shehade, MS Kariolis, ABY Hui, ... Nature communications 7 (1), 13898, 2016 | 170 | 2016 |
| Galectin-1–driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance DK Nambiar, T Aguilera, H Cao, S Kwok, C Kong, J Bloomstein, Z Wang, ... The Journal of clinical investigation 129 (12), 5553-5567, 2019 | 125 | 2019 |
| Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies MS Kariolis, YR Miao, A Diep, SE Nash, MM Olcina, D Jiang, DS Jones, ... The Journal of clinical investigation 127 (1), 183-198, 2017 | 113 | 2017 |
| ATR inhibition potentiates ionizing radiation‐induced interferon response via cytosolic nucleic acid‐sensing pathways X Feng, A Tubbs, C Zhang, M Tang, S Sridharan, C Wang, D Jiang, D Su, ... The EMBO journal 39 (14), e104036, 2020 | 110 | 2020 |
| Loss of the p53/p63 regulated desmosomal protein Perp promotes tumorigenesis VG Beaudry, D Jiang, RL Dusek, EJ Park, S Knezevich, K Ridd, H Vogel, ... PLoS genetics 6 (10), e1001168, 2010 | 109 | 2010 |
| Full p53 transcriptional activation potential is dispensable for tumor suppression in diverse lineages D Jiang, CA Brady, TM Johnson, EY Lee, EJ Park, MP Scott, LD Attardi Proceedings of the National Academy of Sciences 108 (41), 17123-17128, 2011 | 101 | 2011 |
| Chemical space mimicry for drug discovery W Yuan, D Jiang, DK Nambiar, LP Liew, MP Hay, J Bloomstein, P Lu, ... Journal of chemical information and modeling 57 (4), 875-882, 2017 | 96 | 2017 |
| Analysis of p53 Transactivation Domain Mutants Reveals Acad11 as a Metabolic Target Important for p53 Pro-Survival Function D Jiang, EL LaGory, DK Brož, KT Bieging, CA Brady, N Link, JM Abrams, ... CELL REPORTS, 2015 | 65 | 2015 |
| Hypoxic induction of AKAP12 variant 2 shifts PKA-mediated protein phosphorylation to enhance migration and metastasis of melanoma cells EC Finger, L Castellini, EB Rankin, M Vilalta, AJ Krieg, D Jiang, A Banh, ... Proceedings of the National Academy of Sciences 112 (14), 4441-4446, 2015 | 50 | 2015 |
| Identification of doxorubicin as an inhibitor of the IRE1α-XBP1 axis of the unfolded protein response D Jiang, C Lynch, BC Medeiros, M Liedtke, R Bam, AB Tam, Z Yang, ... Scientific reports 6 (1), 33353, 2016 | 35 | 2016 |
| Acridine derivatives as inhibitors of the ire1α–xbp1 pathway are cytotoxic to human multiple myeloma D Jiang, AB Tam, M Alagappan, MP Hay, A Gupta, MM Kozak, ... Molecular cancer therapeutics 15 (9), 2055-2065, 2016 | 35 | 2016 |
| Targeting the Tumor Microenvironment in Radiation Oncology: Proceedings from the 2018 ASTRO–AACR Research Workshop HM McGee, D Jiang, DR Soto-Pantoja, A Nevler, AJ Giaccia, ... Clinical Cancer Research 25 (10), 2969-2974, 2019 | 29 | 2019 |
| Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors X Feng, M Tang, M Dede, D Su, G Pei, D Jiang, C Wang, Z Chen, M Li, ... Science advances 8 (19), eabm6638, 2022 | 26 | 2022 |
| Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes JP Saiki, H Cao, LD Van Wassenhove, V Viswanathan, J Bloomstein, ... Proceedings of the National Academy of Sciences 115 (24), 6279-6284, 2018 | 25 | 2018 |
| Comprehensive analysis of the unfolded protein response in breast cancer subtypes D Jiang, B Turner, J Song, R Li, M Diehn, QT Le, P Khatri, AC Koong JCO precision oncology 1, 1-9, 2017 | 17 | 2017 |
| Engaging the p53 metabolic brake drives senescence D Jiang, LD Attardi Cell research 23 (6), 739-740, 2013 | 16 | 2013 |
| Induced tumor heterogeneity reveals factors informing radiation and immunotherapy combinations TA Aguilera, EA Elghonaimy, H Shehade, M Rafat, L Castellini, D Jiang, ... Clinical Cancer Research 26 (12), 2972-2985, 2020 | 12 | 2020 |
