| Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production A Michelucci, T Cordes, J Ghelfi, A Pailot, N Reiling, O Goldmann, T Binz, ... Proceedings of the National Academy of Sciences 110 (19), 7820-7825, 2013 | 1016 | 2013 |
| Vitamin C: Biosynthesis, recycling and degradation in mammals CL Linster, E Van Schaftingen The FEBS journal 274 (1), 1-22, 2007 | 884 | 2007 |
| Metabolite damage and its repair or pre-emption CL Linster, E Van Schaftingen, AD Hanson Nature chemical biology 9 (2), 72-80, 2013 | 302 | 2013 |
| L-Ascorbate biosynthesis in higher plants: the role of VTC2 CL Linster, SG Clarke Trends in plant science 13 (11), 567-573, 2008 | 267 | 2008 |
| Arabidopsis VTC2 Encodes a GDP-l-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants*♦ CL Linster, TA Gomez, KC Christensen, LN Adler, BD Young, C Brenner, ... Journal of Biological Chemistry 282 (26), 18879-18885, 2007 | 233 | 2007 |
| Extremely conserved ATP-or ADP-dependent enzymatic system for nicotinamide nucleotide repair AY Marbaix, G Noël, AM Detroux, D Vertommen, E Van Schaftingen, ... Journal of Biological Chemistry 286 (48), 41246-41252, 2011 | 130 | 2011 |
| Failure to eliminate a phosphorylated glucose analog leads to neutropenia in patients with G6PT and G6PC3 deficiency M Veiga-da-Cunha, N Chevalier, X Stephenne, JP Defour, N Paczia, ... Proceedings of the National Academy of Sciences 116 (4), 1241-1250, 2019 | 128 | 2019 |
| Millifluidic culture improves human midbrain organoid vitality and differentiation E Berger, C Magliaro, N Paczia, AS Monzel, P Antony, CL Linster, ... Lab on a Chip 18 (20), 3172-3183, 2018 | 126 | 2018 |
| Impact of oxidative stress on ascorbate biosynthesis in Chlamydomonas via regulation of the VTC2 gene encoding a GDP-L-galactose phosphorylase EI Urzica, LN Adler, MD Page, CL Linster, MA Arbing, D Casero, ... Journal of Biological Chemistry 287 (17), 14234-14245, 2012 | 117 | 2012 |
| A conserved phosphatase destroys toxic glycolytic side products in mammals and yeast F Collard, F Baldin, I Gerin, J Bolsée, G Noël, J Graff, M Veiga-da-Cunha, ... Nature chemical biology 12 (8), 601-607, 2016 | 102 | 2016 |
| Metabolite proofreading, a neglected aspect of intermediary metabolism E Van Schaftingen, R Rzem, A Marbaix, F Collard, M Veiga-da-Cunha, ... Journal of inherited metabolic disease 36, 427-434, 2013 | 84 | 2013 |
| Confronting the catalytic dark matter encoded by sequenced genomes KW Ellens, N Christian, C Singh, VP Satagopam, P May, CL Linster Nucleic acids research 45 (20), 11495-11514, 2017 | 78 | 2017 |
| Protocols and programs for high-throughput growth and aging phenotyping in yeast PP Jung, N Christian, DP Kay, A Skupin, CL Linster PloS one 10 (3), e0119807, 2015 | 75 | 2015 |
| A second GDP-L-galactose phosphorylase in Arabidopsis en route to vitamin C: covalent intermediate and substrate requirements for the conserved reaction CL Linster, LN Adler, K Webb, KC Christensen, C Brenner, SG Clarke Journal of Biological Chemistry 283 (27), 18483-18492, 2008 | 75 | 2008 |
| Saccharomyces cerevisiae Forms d-2-Hydroxyglutarate and Couples Its Degradation to d-Lactate Formation via a Cytosolic Transhydrogenase*♦ J Becker-Kettern, N Paczia, JF Conrotte, DP Kay, C Guignard, PP Jung, ... Journal of Biological Chemistry 291 (12), 6036-6058, 2016 | 63 | 2016 |
| NAD (P) HX dehydratase (NAXD) deficiency: a novel neurodegenerative disorder exacerbated by febrile illnesses NJ Van Bergen, Y Guo, J Rankin, N Paczia, J Becker-Kettern, LS Kremer, ... Brain 142 (1), 50-58, 2019 | 57 | 2019 |
| Ethylmalonyl-CoA decarboxylase, a new enzyme involved in metabolite proofreading CL Linster, G Noël, V Stroobant, D Vertommen, MF Vincent, GT Bommer, ... Journal of Biological Chemistry 286 (50), 42992-43003, 2011 | 57 | 2011 |
| Occurrence and subcellular distribution of the NAD (P) HX repair system in mammals AY Marbaix, D Tyteca, TD Niehaus, AD Hanson, CL Linster, ... Biochemical Journal 460 (1), 49-60, 2014 | 51 | 2014 |
| The role of DJ-1 in cellular metabolism and pathophysiological implications for Parkinson’s disease P Mencke, I Boussaad, CD Romano, T Kitami, CL Linster, R Krüger Cells 10 (2), 347, 2021 | 48 | 2021 |
| Nit1 is a metabolite repair enzyme that hydrolyzes deaminated glutathione A Peracchi, M Veiga-da-Cunha, T Kuhara, KW Ellens, N Paczia, ... Proceedings of the National Academy of Sciences 114 (16), E3233-E3242, 2017 | 39 | 2017 |
