Syntheses and crystal structures of mono-, di-and trinuclear cobalt complexes of a salen type ligand J Welby, LN Rusere, JM Tanski, LA Tyler Inorganica Chimica Acta 362 (5), 1405-1411, 2009 | 62 | 2009 |
Dengue virus NS2B/NS3 protease inhibitors exploiting the prime side KH Lin, A Ali, L Rusere, DI Soumana, N Kurt Yilmaz, CA Schiffer Journal of virology 91 (10), 10.1128/jvi. 00045-17, 2017 | 61 | 2017 |
Drug design strategies to avoid resistance in direct-acting antivirals and beyond AN Matthew, F Leidner, GJ Lockbaum, M Henes, J Zephyr, S Hou, ... Chemical reviews 121 (6), 3238-3270, 2021 | 47 | 2021 |
Structural adaptation of darunavir analogues against primary mutations in HIV-1 protease GJ Lockbaum, F Leidner, LN Rusere, M Henes, K Kosovrasti, GS Nachum, ... ACS infectious diseases 5 (2), 316-325, 2018 | 32 | 2018 |
Synthesis and crystal structures of Ni (II), Cu (II) and μ-oxo-Fe (III) complexes of a salen type ligand: Mononuclear versus multinuclear complex formation LN Rusere, T Shalumova, JM Tanski, LA Tyler Polyhedron 28 (17), 3804-3810, 2009 | 29 | 2009 |
HIV-1 protease inhibitors incorporating stereochemically defined P2′ ligands to optimize hydrogen bonding in the substrate envelope LN Rusere, GJ Lockbaum, SK Lee, M Henes, K Kosovrasti, E Spielvogel, ... Journal of medicinal chemistry 62 (17), 8062-8079, 2019 | 24 | 2019 |
Design and synthesis of potent macrocyclic HIV-1 protease inhibitors involving P1–P2 ligands AK Ghosh, GE Schiltz, LN Rusere, HL Osswald, DE Walters, M Amano, ... Organic & biomolecular chemistry 12 (35), 6842-6854, 2014 | 19 | 2014 |
Quinoxaline-based linear HCV NS3/4A protease inhibitors exhibit potent activity against drug resistant variants LN Rusere, AN Matthew, GJ Lockbaum, M Jahangir, A Newton, ... ACS Medicinal Chemistry Letters 9 (7), 691-696, 2018 | 18 | 2018 |
Inhibiting HTLV-1 protease: a viable antiviral target GJ Lockbaum, M Henes, N Talledge, LN Rusere, K Kosovrasti, ... ACS chemical biology 16 (3), 529-538, 2021 | 15 | 2021 |
Structural analysis of potent hybrid HIV-1 protease inhibitors containing Bis-tetrahydrofuran in a Pseudosymmetric dipeptide Isostere LN Rusere, GJ Lockbaum, M Henes, SK Lee, E Spielvogel, DN Rao, ... Journal of medicinal chemistry 63 (15), 8296-8313, 2020 | 6 | 2020 |
HIV-1 protease inhibitors with a P1 phosphonate modification maintain potency against drug-resistant variants by increased interactions with flap residues GJ Lockbaum, LN Rusere, M Henes, K Kosovrasti, DN Rao, E Spielvogel, ... European Journal of Medicinal Chemistry 257, 115501, 2023 | 4 | 2023 |
Correction to Structural Adaptation of Darunavir Analogues against Primary Mutations in HIV-1 Protease GJ Lockbaum, F Leidner, LN Rusere, M Henes, K Kosovrasti, GS Nachum, ... ACS infectious diseases 5 (6), 1044-1044, 2019 | 1 | 2019 |
Structural adaptation of Darunavir analogs against primary resistance mutations in HIV-1 protease GJ Lockbaum, F Leidner, LN Rusere, M Henes, K Kosovrasti, ... BioRxiv, 406637, 2018 | 1 | 2018 |
Antiviral Compounds CA SCHIFFER, A Ali, N Kurt-Yilmaz, LN Rusere, GJ Lockbaum, M Henes US Patent App. 18/074,219, 2023 | | 2023 |
Antiviral compounds CA Schiffer, A Ali, N Kurt-Yilmaz, LN Rusere, GJ Lockbaum, M Henes US Patent 11,542,288, 2023 | | 2023 |
Structure-guided design and SAR studies of hepatitis C virus NS3/4A protease inhibitors incorporating flexible P2 quinoxalines A Ali, A Matthew, NR Desaboini, L Rusere, A Newton, C Petropoulos, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |
Structure-based design, synthesis, evaluation and x-ray crystal structure analysis of HIV-1 protease inhibitors with modified P1, P1'and P2'groups L Rusere, A Ali, G Lockbaum, SK Lee, R Swanstrom, C Schiffer ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |
Structural Analysis of Darunavir Analogs Against Primary Resistance Mutations in HIV Protease GJ Lockbaum, F Leidner, L Rusere, E Nalivaika, A Ali, N Kurt‐Yilmaz, ... The FASEB Journal 32, 797.8-797.8, 2018 | | 2018 |
Dengue virus NS2B/NS3 protease inhibitors exploiting the prime side. LKH Lin KuanHung, A Ali, L Rusere, DI Soumana, NK Yilmaz, CA Schiffer | | 2017 |
Design of hepatitis C virus NS3/4A protease iInhibitors with improved activity against drug resistant variants A Ali, D Soumana, K Prachanronarong, A Ozen, A Matthew, LN Rusere, ... Abstracts of Papers of the American Chemical Society 250, 2015 | | 2015 |