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Daniel Leahy
Daniel Leahy
Professor of Molecular Biosciences, University of Texas at Austin
在 austin.utexas.edu 的电子邮件经过验证
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引用次数
引用次数
年份
Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab
HS Cho, K Mason, KX Ramyar, AM Stanley, SB Gabelli, DW Denney Jr, ...
Nature 421 (6924), 756-760, 2003
20232003
Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex
MC Franklin, KD Carey, FF Vajdos, DJ Leahy, AM De Vos, MX Sliwkowski
Cancer cell 5 (4), 317-328, 2004
14152004
An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors
AW Burgess, HS Cho, C Eigenbrot, KM Ferguson, TPJ Garrett, DJ Leahy, ...
Molecular cell 12 (3), 541-552, 2003
13102003
EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization
KM Ferguson, MB Berger, JM Mendrola, HS Cho, DJ Leahy, MA Lemmon
Molecular cell 11 (2), 507-517, 2003
10192003
2.0 Å crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region
DJ Leahy, I Aukhil, HP Erickson
Cell 84 (1), 155-164, 1996
9021996
Functionally significant insulin-like growth factor I receptor mutations in centenarians
Y Suh, G Atzmon, MO Cho, D Hwang, B Liu, DJ Leahy, N Barzilai, ...
Proceedings of the National Academy of Sciences 105 (9), 3438-3442, 2008
8742008
Structure of a fibronectin type III domain from tenascin phased by MAD analysis of the selenomethionyl protein
DJ Leahy, WA Hendrickson, lkramuddin Aukhil, HP Erickson
Science 258 (5084), 987-991, 1992
7121992
Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains
CE Dann, JC Hsieh, A Rattner, D Sharma, J Nathans, DJ Leahy
Nature 412 (6842), 86-90, 2001
6422001
Transient mammalian cell transfection with polyethylenimine (PEI)
PA Longo, JM Kavran, MS Kim, DJ Leahy
Methods in enzymology 529, 227-240, 2013
6282013
Structure of the extracellular region of HER3 reveals an interdomain tether
HS Cho, DJ Leahy
Science 297 (5585), 1330-1333, 2002
6002002
Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain
JC Lee, I Vivanco, R Beroukhim, JHY Huang, WL Feng, RM DeBiasi, ...
PLoS medicine 3 (12), e485, 2006
4232006
Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrin.
A Qu, DJ Leahy
Proceedings of the National Academy of Sciences 92 (22), 10277-10281, 1995
4191995
Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 Å resolution
DJ Leahy, R Axel, WA Hendrickson
Cell 68 (6), 1145-1162, 1992
3651992
Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins
TMT Hall, JA Porter, KE Young, EV Koonin, PA Beachy, DJ Leahy
Cell 91 (1), 85-97, 1997
3311997
EGFR ligands differentially stabilize receptor dimers to specify signaling kinetics
DM Freed, NJ Bessman, A Kiyatkin, E Salazar-Cavazos, PO Byrne, ...
Cell 171 (3), 683-695. e18, 2017
3262017
Mutations in the TGF-β repressor SKI cause Shprintzen-Goldberg syndrome with aortic aneurysm
DHC Doyle AJ1, Doyle JJ, Bessling SL, Maragh S, Lindsay ME, Schepers D ...
Nature Genetics 44 (11), 1249-54, 2012
3042012
Glucose and weight control in mice with a designed ghrelin O-acyltransferase inhibitor
BP Barnett, Y Hwang, MS Taylor, H Kirchner, PT Pfluger, V Bernard, Y Lin, ...
Science 330 (6011), 1689-1692, 2010
2972010
A potential catalytic site revealed by the 1.7-Å crystal structure of the amino-terminal signalling domain of Sonic hedgehog
TMT Hall, JA Porter, PA Beachy, DJ Leahy
Nature 378 (6553), 212-216, 1995
2711995
Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165
C Gu, BJ Limberg, GB Whitaker, B Perman, DJ Leahy, JS Rosenbaum, ...
Journal of Biological Chemistry 277 (20), 18069-18076, 2002
2702002
Interactions between Hedgehog proteins and their binding partners come into view
PA Beachy, SG Hymowitz, RA Lazarus, DJ Leahy, C Siebold
Genes & development 24 (18), 2001-2012, 2010
2692010
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