关注
Manoja Kumar Brahma, PhD
Manoja Kumar Brahma, PhD
Senior Study Director, Sygnature Discovery
在 sygnaturediscovery.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Metabolic origins of heart failure
AR Wende, MK Brahma, GR McGinnis, ME Young
Basic to Translational Science 2 (3), 297-310, 2017
1882017
Discovery and development of selective PPARγ modulators as safe and effective antidiabetic agents
LS Doshi, MK Brahma, UA Bahirat, AV Dixit, KVS Nemmani
Expert opinion on investigational drugs 19 (4), 489-512, 2010
802010
FGF21 IS INDUCED UPON CARDIAC STRESS AND ALTERS CARDIAC LIPID HOMEOSTASIS
HG Brahma MK, Adam RC, Pollak NM, Jaeger D, Zierler KA, Poecher N, Schreiber ...
Journal of Lipid Research, 2014
68*2014
Genetic disruption of the cardiomyocyte circadian clock differentially influences insulin-mediated processes in the heart
GR McGinnis, Y Tang, RA Brewer, MK Brahma, HL Stanley, ...
Journal of molecular and cellular cardiology 110, 80-95, 2017
672017
Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits
BR Chandrika, A Kulkarni-Almeida, KV Katkar, S Khanna, U Ghosh, ...
Bioorganic & medicinal chemistry 20 (9), 2930-2939, 2012
632012
Synthesis and biological evaluation of isoxazole, oxazole, and oxadiazole containing heteroaryl analogs of biaryl ureas as DGAT1 inhibitors
RD Jadhav, KS Kadam, S Kandre, T Guha, MMK Reddy, MK Brahma, ...
European journal of medicinal chemistry 54, 324-342, 2012
612012
My sweetheart is broken: role of glucose in diabetic cardiomyopathy
MK Brahma, ME Pepin, AR Wende
Diabetes & metabolism journal 41 (1), 1-9, 2017
602017
Maintaining myocardial glucose utilization in diabetic cardiomyopathy accelerates mitochondrial dysfunction
AR Wende, JC Schell, CM Ha, ME Pepin, O Khalimonchuk, H Schwertz, ...
Diabetes 69 (10), 2094-2111, 2020
572020
Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses
AR Wende, J Kim, WL Holland, BE Wayment, BT O’Neill, J Tuinei, ...
American Journal of Physiology-Heart and Circulatory Physiology 313 (6 …, 2017
542017
Isocytosine-based inhibitors of xanthine oxidase: Design, synthesis, SAR, PK and in vivo efficacy in rat model of hyperuricemia
S Khanna, S Burudkar, K Bajaj, P Shah, A Keche, U Ghosh, A Desai, ...
Bioorganic & medicinal chemistry letters 22 (24), 7543-7546, 2012
522012
Increased glucose availability attenuates myocardial ketone body utilization
MK Brahma, CM Ha, ME Pepin, S Mia, Z Sun, JC Chatham, KM Habegger, ...
Journal of the American Heart Association 9 (15), e013039, 2020
482020
Acute administration of GPR40 receptor agonist potentiates glucose-stimulated insulin secretion in vivo in the rat
LS Doshi, MK Brahma, SG Sayyed, AV Dixit, PG Chandak, V Pamidiboina, ...
Metabolism 58 (3), 333-343, 2009
442009
Oxidative stress in obesity-associated hepatocellular carcinoma: sources, signaling and therapeutic challenges
MK Brahma, EH Gilglioni, L Zhou, E Trépo, P Chen, EN Gurzov
Oncogene 40 (33), 5155-5167, 2021
372021
Fermentation, Isolation, Structure, and antidiabetic activity of NFAT-133 produced by Streptomyces strain PM0324667
AA Kulkarni-Almeida, MK Brahma, P Padmanabhan, PD Mishra, ...
AMB express 1, 1-12, 2011
302011
The neuronal apoptotic death in global cerebral ischemia in gerbil: important role for sodium channel modulator
MK Brahma, P Dohare, S Varma, SK Rath, P Garg, PK Biswal, ...
Journal of neuroscience research 87 (6), 1400-1411, 2009
252009
Antiretroviral therapy potentiates high-fat diet induced obesity and glucose intolerance
ME Pepin, LE Padgett, RE McDowell, AR Burg, MK Brahma, C Holleman, ...
Molecular metabolism 12, 48-61, 2018
242018
Temporal partitioning of adaptive responses of the murine heart to fasting
RA Brewer, HE Collins, RD Berry, MK Brahma, BA Tirado, ...
Life sciences 197, 30-39, 2018
172018
Exploration of pyridine containing heteroaryl analogs of biaryl ureas as DGAT1 inhibitors
H Motiwala, S Kandre, V Birar, KS Kadam, A Rodge, RD Jadhav, ...
Bioorganic & medicinal chemistry letters 21 (19), 5812-5817, 2011
172011
Evaluation of thiazole containing biaryl analogs as diacylglycerol acyltransferase 1 (DGAT1) inhibitors
KS Kadam, RD Jadhav, S Kandre, T Guha, MMK Reddy, MK Brahma, ...
European Journal of Medicinal Chemistry 65, 337-347, 2013
162013
PTPN2 regulates the interferon signaling and endoplasmic reticulum stress response in pancreatic β-cells in autoimmune diabetes
B Elvira, V Vandenbempt, J Bauzá-Martinez, R Crutzen, J Negueruela, ...
Diabetes 71 (4), 653-668, 2022
122022
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