Metabolic origins of heart failure AR Wende, MK Brahma, GR McGinnis, ME Young Basic to Translational Science 2 (3), 297-310, 2017 | 188 | 2017 |
Discovery and development of selective PPARγ modulators as safe and effective antidiabetic agents LS Doshi, MK Brahma, UA Bahirat, AV Dixit, KVS Nemmani Expert opinion on investigational drugs 19 (4), 489-512, 2010 | 80 | 2010 |
FGF21 IS INDUCED UPON CARDIAC STRESS AND ALTERS CARDIAC LIPID HOMEOSTASIS HG Brahma MK, Adam RC, Pollak NM, Jaeger D, Zierler KA, Poecher N, Schreiber ... Journal of Lipid Research, 2014 | 68* | 2014 |
Genetic disruption of the cardiomyocyte circadian clock differentially influences insulin-mediated processes in the heart GR McGinnis, Y Tang, RA Brewer, MK Brahma, HL Stanley, ... Journal of molecular and cellular cardiology 110, 80-95, 2017 | 67 | 2017 |
Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits BR Chandrika, A Kulkarni-Almeida, KV Katkar, S Khanna, U Ghosh, ... Bioorganic & medicinal chemistry 20 (9), 2930-2939, 2012 | 63 | 2012 |
Synthesis and biological evaluation of isoxazole, oxazole, and oxadiazole containing heteroaryl analogs of biaryl ureas as DGAT1 inhibitors RD Jadhav, KS Kadam, S Kandre, T Guha, MMK Reddy, MK Brahma, ... European journal of medicinal chemistry 54, 324-342, 2012 | 61 | 2012 |
My sweetheart is broken: role of glucose in diabetic cardiomyopathy MK Brahma, ME Pepin, AR Wende Diabetes & metabolism journal 41 (1), 1-9, 2017 | 60 | 2017 |
Maintaining myocardial glucose utilization in diabetic cardiomyopathy accelerates mitochondrial dysfunction AR Wende, JC Schell, CM Ha, ME Pepin, O Khalimonchuk, H Schwertz, ... Diabetes 69 (10), 2094-2111, 2020 | 57 | 2020 |
Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses AR Wende, J Kim, WL Holland, BE Wayment, BT O’Neill, J Tuinei, ... American Journal of Physiology-Heart and Circulatory Physiology 313 (6 …, 2017 | 54 | 2017 |
Isocytosine-based inhibitors of xanthine oxidase: Design, synthesis, SAR, PK and in vivo efficacy in rat model of hyperuricemia S Khanna, S Burudkar, K Bajaj, P Shah, A Keche, U Ghosh, A Desai, ... Bioorganic & medicinal chemistry letters 22 (24), 7543-7546, 2012 | 52 | 2012 |
Increased glucose availability attenuates myocardial ketone body utilization MK Brahma, CM Ha, ME Pepin, S Mia, Z Sun, JC Chatham, KM Habegger, ... Journal of the American Heart Association 9 (15), e013039, 2020 | 48 | 2020 |
Acute administration of GPR40 receptor agonist potentiates glucose-stimulated insulin secretion in vivo in the rat LS Doshi, MK Brahma, SG Sayyed, AV Dixit, PG Chandak, V Pamidiboina, ... Metabolism 58 (3), 333-343, 2009 | 44 | 2009 |
Oxidative stress in obesity-associated hepatocellular carcinoma: sources, signaling and therapeutic challenges MK Brahma, EH Gilglioni, L Zhou, E Trépo, P Chen, EN Gurzov Oncogene 40 (33), 5155-5167, 2021 | 37 | 2021 |
Fermentation, Isolation, Structure, and antidiabetic activity of NFAT-133 produced by Streptomyces strain PM0324667 AA Kulkarni-Almeida, MK Brahma, P Padmanabhan, PD Mishra, ... AMB express 1, 1-12, 2011 | 30 | 2011 |
The neuronal apoptotic death in global cerebral ischemia in gerbil: important role for sodium channel modulator MK Brahma, P Dohare, S Varma, SK Rath, P Garg, PK Biswal, ... Journal of neuroscience research 87 (6), 1400-1411, 2009 | 25 | 2009 |
Antiretroviral therapy potentiates high-fat diet induced obesity and glucose intolerance ME Pepin, LE Padgett, RE McDowell, AR Burg, MK Brahma, C Holleman, ... Molecular metabolism 12, 48-61, 2018 | 24 | 2018 |
Temporal partitioning of adaptive responses of the murine heart to fasting RA Brewer, HE Collins, RD Berry, MK Brahma, BA Tirado, ... Life sciences 197, 30-39, 2018 | 17 | 2018 |
Exploration of pyridine containing heteroaryl analogs of biaryl ureas as DGAT1 inhibitors H Motiwala, S Kandre, V Birar, KS Kadam, A Rodge, RD Jadhav, ... Bioorganic & medicinal chemistry letters 21 (19), 5812-5817, 2011 | 17 | 2011 |
Evaluation of thiazole containing biaryl analogs as diacylglycerol acyltransferase 1 (DGAT1) inhibitors KS Kadam, RD Jadhav, S Kandre, T Guha, MMK Reddy, MK Brahma, ... European Journal of Medicinal Chemistry 65, 337-347, 2013 | 16 | 2013 |
PTPN2 regulates the interferon signaling and endoplasmic reticulum stress response in pancreatic β-cells in autoimmune diabetes B Elvira, V Vandenbempt, J Bauzá-Martinez, R Crutzen, J Negueruela, ... Diabetes 71 (4), 653-668, 2022 | 12 | 2022 |