| Robust deep learning–based protein sequence design using ProteinMPNN J Dauparas, I Anishchenko, N Bennett, H Bai, RJ Ragotte, LF Milles, ... Science 378 (6615), 49-56, 2022 | 644 | 2022 |
| De novo design of protein structure and function with RFdiffusion JL Watson, D Juergens, NR Bennett, BL Trippe, J Yim, HE Eisenach, ... Nature 620 (7976), 1089-1100, 2023 | 455 | 2023 |
| De novo protein design by deep network hallucination I Anishchenko, SJ Pellock, TM Chidyausiku, TA Ramelot, S Ovchinnikov, ... Nature 600 (7889), 547-552, 2021 | 437 | 2021 |
| Structure and inhibition of microbiome β-glucuronidases essential to the alleviation of cancer drug toxicity BD Wallace, AB Roberts, RM Pollet, JD Ingle, KA Biernat, SJ Pellock, ... Chemistry & biology 22 (9), 1238-1249, 2015 | 260 | 2015 |
| An atlas of β-glucuronidases in the human intestinal microbiome RM Pollet, EH D'Agostino, WG Walton, Y Xu, MS Little, KA Biernat, ... Structure 25 (7), 967-977. e5, 2017 | 238 | 2017 |
| Glucuronides in the gut: Sugar-driven symbioses between microbe and host SJ Pellock, MR Redinbo Journal of Biological Chemistry 292 (21), 8569-8576, 2017 | 196 | 2017 |
| De novo design of luciferases using deep learning AHW Yeh, C Norn, Y Kipnis, D Tischer, SJ Pellock, D Evans, P Ma, ... Nature 614 (7949), 774-780, 2023 | 194 | 2023 |
| Broadly applicable and accurate protein design by integrating structure prediction networks and diffusion generative models JL Watson, D Juergens, NR Bennett, BL Trippe, J Yim, HE Eisenach, ... BioRxiv, 2022.12. 09.519842, 2022 | 176 | 2022 |
| Targeted inhibition of gut bacterial β-glucuronidase activity enhances anticancer drug efficacy AP Bhatt, SJ Pellock, KA Biernat, WG Walton, BD Wallace, BC Creekmore, ... Proceedings of the National Academy of Sciences 117 (13), 7374-7381, 2020 | 154 | 2020 |
| Structure, function, and inhibition of drug reactivating human gut microbial β-glucuronidases KA Biernat, SJ Pellock, AP Bhatt, MM Bivins, WG Walton, BNT Tran, L Wei, ... Scientific reports 9 (1), 825, 2019 | 83 | 2019 |
| Structural basis for the regulation of β-glucuronidase expression by human gut Enterobacteriaceae MS Little, SJ Pellock, WG Walton, A Tripathy, MR Redinbo Proceedings of the National Academy of Sciences 115 (2), E152-E161, 2018 | 69 | 2018 |
| Gut microbial β-glucuronidase inhibition via catalytic cycle interception SJ Pellock, BC Creekmore, WG Walton, N Mehta, KA Biernat, AP Cesmat, ... ACS central science 4 (7), 868-879, 2018 | 67 | 2018 |
| Three structurally and functionally distinct β-glucuronidases from the human gut microbe Bacteroides uniformis SJ Pellock, WG Walton, KA Biernat, D Torres-Rivera, BC Creekmore, Y Xu, ... Journal of Biological Chemistry 293 (48), 18559-18573, 2018 | 63 | 2018 |
| Discovering the microbial enzymes driving drug toxicity with activity-based protein profiling PB Jariwala, SJ Pellock, D Goldfarb, EW Cloer, M Artola, JB Simpson, ... ACS chemical biology 15 (1), 217-225, 2019 | 61 | 2019 |
| Garcinoic acid is a natural and selective agonist of pregnane X receptor D Bartolini, F De Franco, P Torquato, R Marinelli, B Cerra, R Ronchetti, ... Journal of medicinal chemistry 63 (7), 3701-3712, 2020 | 39 | 2020 |
| Improving protein expression, stability, and function with ProteinMPNN KH Sumida, R Núñez-Franco, I Kalvet, SJ Pellock, BIM Wicky, LF Milles, ... Journal of the American Chemical Society 146 (3), 2054-2061, 2024 | 37 | 2024 |
| Examination of tyrosine/adenine stacking interactions in protein complexes KL Copeland, SJ Pellock, JR Cox, ML Cafiero, GS Tschumper The Journal of Physical Chemistry B 117 (45), 14001-14008, 2013 | 27 | 2013 |
| Discovery and characterization of FMN-binding β-glucuronidases in the human gut microbiome SJ Pellock, WG Walton, SM Ervin, D Torres-Rivera, BC Creekmore, ... Journal of molecular biology 431 (5), 970-980, 2019 | 26 | 2019 |
| Combining content and elements of communication into an upper‐level biochemistry course CP Whittington, SJ Pellock, RL Cunningham, JR Cox Biochemistry and molecular biology education 42 (2), 136-141, 2014 | 19 | 2014 |
| Selecting a single stereocenter: The molecular nuances that differentiate β-hexuronidases in the human gut microbiome SJ Pellock, WG Walton, MR Redinbo Biochemistry 58 (9), 1311-1317, 2019 | 14 | 2019 |
Matthew RedinboUniversity of North Carolina at Chapel Hill在 unc.edu 的电子邮件经过验证
