| Good vibrations in enzyme-catalysed reactions S Hay, NS Scrutton Nature chemistry 4 (3), 161-168, 2012 | 310 | 2012 |
| Reductive dehalogenase structure suggests a mechanism for B12-dependent dehalogenation KAP Payne, CP Quezada, K Fisher, MS Dunstan, FA Collins, H Sjuts, ... Nature 517 (7535), 513-516, 2015 | 294 | 2015 |
| New cofactor supports α, β-unsaturated acid decarboxylation via 1, 3-dipolar cycloaddition KAP Payne, MD White, K Fisher, B Khara, SS Bailey, D Parker, ... Nature 522 (7557), 497-501, 2015 | 226 | 2015 |
| UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis MD White, KAP Payne, K Fisher, SA Marshall, D Parker, NJW Rattray, ... Nature 522 (7557), 502-506, 2015 | 199 | 2015 |
| Quantum biology: An update and perspective Y Kim, F Bertagna, EM D’souza, DJ Heyes, LO Johannissen, ET Nery, ... Quantum Reports 3 (1), 80-126, 2021 | 131 | 2021 |
| Promoting motions in enzyme catalysis probed by pressure studies of kinetic isotope effects S Hay, MJ Sutcliffe, NS Scrutton Proceedings of the National Academy of Sciences 104 (2), 507-512, 2007 | 120 | 2007 |
| Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis S Zhang, DJ Heyes, L Feng, W Sun, LO Johannissen, H Liu, CW Levy, ... Nature 574 (7780), 722-725, 2019 | 112 | 2019 |
| Fast protein motions are coupled to enzyme H-transfer reactions CR Pudney, A Guerriero, NJ Baxter, LO Johannissen, JP Waltho, S Hay, ... Journal of the American Chemical Society 135 (7), 2512-2517, 2013 | 102 | 2013 |
| Direct Analysis of Donor− Acceptor Distance and Relationship to Isotope Effects and the Force Constant for Barrier Compression in Enzymatic H-Tunneling Reactions CR Pudney, LO Johannissen, MJ Sutcliffe, S Hay, NS Scrutton Journal of the American Chemical Society 132 (32), 11329-11335, 2010 | 94 | 2010 |
| Evidence to support the hypothesis that promoting vibrations enhance the rate of an enzyme catalyzed H-tunneling reaction CR Pudney, S Hay, C Levy, J Pang, MJ Sutcliffe, D Leys, NS Scrutton Journal of the American Chemical Society 131 (47), 17072-17073, 2009 | 92 | 2009 |
| Deep tunneling dominates the biologically important hydride transfer reaction from NADH to FMN in morphinone reductase J Pang, S Hay, NS Scrutton, MJ Sutcliffe Journal of the American Chemical Society 130 (22), 7092-7097, 2008 | 89 | 2008 |
| Carboxylesterase converts Amplex red to resorufin: Implications for mitochondrial H2O2 release assays S Miwa, A Treumann, A Bell, G Vistoli, G Nelson, S Hay, T von Zglinicki Free Radical Biology and Medicine 90, 173-183, 2016 | 85 | 2016 |
| α-Secondary isotope effects as probes of “tunneling-ready” configurations in enzymatic H-tunneling: Insight from environmentally coupled tunneling models CR Pudney, S Hay, MJ Sutcliffe, NS Scrutton Journal of the American Chemical Society 128 (43), 14053-14058, 2006 | 84 | 2006 |
| Proton tunneling in aromatic amine dehydrogenase is driven by a short-range sub-picosecond promoting vibration: consistency of simulation and theory with experiment LO Johannissen, S Hay, NS Scrutton, MJ Sutcliffe The Journal of Physical Chemistry B 111 (10), 2631-2638, 2007 | 70 | 2007 |
| Nature of the energy landscape for gated electron transfer in a dynamic redox protein S Hay, S Brenner, B Khara, AM Quinn, SEJ Rigby, NS Scrutton Journal of the American Chemical Society 132 (28), 9738-9745, 2010 | 69 | 2010 |
| Barrier compression enhances an enzymatic hydrogen‐transfer reaction S Hay, CR Pudney, TA McGrory, J Pang, MJ Sutcliffe, NS Scrutton Angewandte Chemie International Edition 48 (8), 1452-1454, 2009 | 69 | 2009 |
| Structural basis of catalysis in the bacterial monoterpene synthases linalool synthase and 1, 8-cineole synthase V Karuppiah, KE Ranaghan, NGH Leferink, LO Johannissen, ... Acs Catalysis 7 (9), 6268-6282, 2017 | 67 | 2017 |
| Mutagenesis of morphinone reductase induces multiple reactive configurations and identifies potential ambiguity in kinetic analysis of enzyme tunneling mechanisms CR Pudney, S Hay, J Pang, C Costello, D Leys, MJ Sutcliffe, NS Scrutton Journal of the American Chemical Society 129 (45), 13949-13956, 2007 | 65 | 2007 |
| Decoupled associative and dissociative processes in strong yet highly dynamic host–guest complexes EA Appel, F Biedermann, D Hoogland, J Del Barrio, MD Driscoll, S Hay, ... Journal of the American Chemical Society 139 (37), 12985-12993, 2017 | 63 | 2017 |
| Conformational and thermodynamic control of electron transfer in neuronal nitric oxide synthase AJ Dunford, SEJ Rigby, S Hay, AW Munro, NS Scrutton Biochemistry 46 (17), 5018-5029, 2007 | 63 | 2007 |
Nigel ScruttonProfessor of Enzymology, Manchester Institute of Biotechnology (MIB) and School of Chemistry在 manchester.ac.uk 的电子邮件经过验证
