Histone modifications at human enhancers reflect global cell-type-specific gene expression ND Heintzman, GC Hon, RD Hawkins, P Kheradpour, A Stark, LF Harp, ... Nature 459 (7243), 108-112, 2009 | 2883 | 2009 |
Chromatin architecture reorganization during stem cell differentiation JR Dixon, I Jung, S Selvaraj, Y Shen, JE Antosiewicz-Bourget, AY Lee, ... Nature 518 (7539), 331-336, 2015 | 1710 | 2015 |
A map of the cis-regulatory sequences in the mouse genome Y Shen, F Yue, DF McCleary, Z Ye, L Edsall, S Kuan, U Wagner, J Dixon, ... Nature 488 (7409), 116-120, 2012 | 1545 | 2012 |
Analysis of the vertebrate insulator protein CTCF-binding sites in the human genome TH Kim, ZK Abdullaev, AD Smith, KA Ching, DI Loukinov, RD Green, ... Cell 128 (6), 1231-1245, 2007 | 1251 | 2007 |
CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease R Ohlsson, R Renkawitz, V Lobanenkov TRENDS in Genetics 17 (9), 520-527, 2001 | 773 | 2001 |
An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc … GN Filippova, S Fagerlie, EM Klenova, C Myers, Y Dehner, G Goodwin, ... Molecular and cellular biology, 1996 | 698 | 1996 |
CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2 S Kurukuti, VK Tiwari, G Tavoosidana, E Pugacheva, A Murrell, Z Zhao, ... Proceedings of the national academy of sciences 103 (28), 10684-10689, 2006 | 637 | 2006 |
Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive C Kanduri, V Pant, D Loukinov, E Pugacheva, CF Qi, A Wolffe, R Ohlsson, ... Current Biology 10 (14), 853-856, 2000 | 562 | 2000 |
A novel sequence-specific DNA binding protein which interacts with three regularly spaced direct repeats of the CCCTC-motif in the 5′-flanking sequence of the chicken c-myc gene VV Lobanenkov, RH Nicolas, VV Adler, H Paterson, EM Klenova, ... Oncogene 5 (12), 1743-1753, 1990 | 519 | 1990 |
BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved … DI Loukinov, E Pugacheva, S Vatolin, SD Pack, H Moon, I Chernukhin, ... Proceedings of the National Academy of Sciences 99 (10), 6806-6811, 2002 | 440 | 2002 |
CTCF-binding sites flank CTG/CAG repeats and form a methylation-sensitive insulator at the DM1 locus GN Filippova, CP Thienes, BH Penn, DH Cho, YJ Hu, JM Moore, ... Nature genetics 28 (4), 335-343, 2001 | 402 | 2001 |
CTCF, a conserved nuclear factor required for optimal transcriptional activity of the chicken c-myc gene, is an 11-Zn-finger protein differentially expressed in multiple forms EM Klenova, RH Nicolas, HF Paterson, AF Carne, CM Heath, ... Molecular and cellular biology, 1993 | 372 | 1993 |
The novel BORIS+ CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer EM Klenova, HC Morse III, R Ohlsson, VV Lobanenkov Seminars in cancer biology 12 (5), 399-414, 2002 | 342 | 2002 |
A genome-wide map of CTCF multivalency redefines the CTCF code H Nakahashi, KRK Kwon, W Resch, L Vian, M Dose, D Stavreva, O Hakim, ... Cell reports 3 (5), 1678-1689, 2013 | 337 | 2013 |
Poly (ADP-ribosyl) ation regulates CTCF-dependent chromatin insulation W Yu, V Ginjala, V Pant, I Chernukhin, J Whitehead, F Docquier, D Farrar, ... Nature genetics 36 (10), 1105-1110, 2004 | 335 | 2004 |
CTCF is conserved from Drosophila to humans and confers enhancer blocking of the Fab‐8 insulator H Moon, G Filippova, D Loukinov, E Pugacheva, Q Chen, ST Smith, ... EMBO reports 6 (2), 165-170, 2005 | 302 | 2005 |
Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene S Renaud, D Loukinov, Z Abdullaev, I Guilleret, FT Bosman, ... Nucleic acids research 35 (4), 1245-1256, 2007 | 276 | 2007 |
Conditional expression of the CTCF-paralogous transcriptional factor BORIS in normal cells results in demethylation and derepression of MAGE-A1 and reactivation of other cancer … S Vatolin, Z Abdullaev, SD Pack, PT Flanagan, M Custer, DI Loukinov, ... Cancer research 65 (17), 7751-7762, 2005 | 234 | 2005 |
Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter its DNA-binding specificity GN Filippova, CF Qi, JE Ulmer, JM Moore, MD Ward, YJ Hu, DI Loukinov, ... Cancer research 62 (1), 48-52, 2002 | 233 | 2002 |
Reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter coincides with derepression of this cancer-testis gene in lung cancer cells JA Hong, Y Kang, Z Abdullaev, PT Flanagan, SD Pack, MR Fischette, ... Cancer research 65 (17), 7763-7774, 2005 | 226 | 2005 |