Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes JW Blanchard, M Bula, J Davila-Velderrain, LA Akay, L Zhu, A Frank, ... Nature medicine 26 (6), 952-963, 2020 | 202 | 2020 |
APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia G Sienski, P Narayan, JM Bonner, N Kory, S Boland, AA Arczewska, ... Science translational medicine 13 (583), eaaz4564, 2021 | 188 | 2021 |
APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes JW Blanchard, LA Akay, J Davila-Velderrain, D von Maydell, H Mathys, ... Nature 611 (7937), 769-779, 2022 | 165 | 2022 |
Cell of all trades: oligodendrocyte precursor cells in synaptic, vascular, and immune function LA Akay, AH Effenberger, LH Tsai Genes & development 35 (3-4), 180-198, 2021 | 88 | 2021 |
Elucidating the control and development of skin patterning in cuttlefish S Reiter, P Hülsdunk, T Woo, MA Lauterbach, JS Eberle, LA Akay, ... Nature 562 (7727), 361-366, 2018 | 82 | 2018 |
PICALM rescues endocytic defects caused by the Alzheimer’s disease risk factor APOE4 P Narayan, G Sienski, JM Bonner, YT Lin, J Seo, V Baru, A Haque, B Milo, ... Cell reports 33 (1), 2020 | 55 | 2020 |
Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer’s disease N Sun, LA Akay, MH Murdock, Y Park, F Galiana-Melendez, A Bubnys, ... Nature neuroscience 26 (6), 970-982, 2023 | 27 | 2023 |
Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration N Morshed, WT Ralvenius, A Nott, LA Watson, FH Rodriguez, LA Akay, ... Molecular Systems Biology 16 (12), e9819, 2020 | 22 | 2020 |
APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia. Sci Transl Med 13 G Sienski, P Narayan, JM Bonner, N Kory, S Boland, AA Arczewska, ... | 10 | 2021 |
Single-cell multi-region dissection of brain vasculature in Alzheimer’s Disease N Sun, LA Akay, MH Murdock, Y Park, A Bubnys, K Galani, H Mathys, ... Biorxiv, 2022.02. 09.479797, 2022 | 6 | 2022 |
Reconstruction of the Human Blood-Brain Barrier JW Blanchard, M Bula, J Davila-Velderrain, LA Akay, L Zhu, A Frank, ... vitro, 2020 | 5 | 2020 |
PICALM rescues endocytic defects caused by the Alzheimer’s disease risk factor APOE4. Cell Rep. 33, 108224 P Narayan, G Sienski, JM Bonner, YT Lin, J Seo, V Baru, A Haque, B Milo, ... | 5 | 2020 |
Author Correction: Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes JW Blanchard, M Bula, J Davila-Velderrain, LA Akay, L Zhu, A Frank, ... Nature Medicine 27 (2), 356-356, 2021 | 4 | 2021 |
Multisensory gamma stimulation promotes glymphatic clearance of amyloid MH Murdock, CY Yang, N Sun, PC Pao, C Blanco-Duque, MC Kahn, ... Nature, 1-8, 2024 | 1 | 2024 |
Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer's disease (vol 26, pg 970, 2023) N Sun, LA Akay, MH Murdock, Y Park, F Galiana-Melendez, A Bubnys, ... NATURE NEUROSCIENCE 26 (12), 2251-2251, 2023 | | 2023 |
Author Correction: Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer's disease N Sun, LA Akay, MH Murdock, Y Park, F Galiana-Melendez, A Bubnys, ... Nature neuroscience 26 (12), 2251, 2023 | | 2023 |
APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes LH Tsai, LA Akay, J Blanchard, DK Von Maydell, M Kellis, DAA Bennett, ... Alzheimer's & Dementia 19, e071948, 2023 | | 2023 |
Associations between APOE genotype and myelin changes in aging and Alzheimer’s disease J Blanchard, LA Akay, DK Von Maydell, J Davila, N Suhy, LH Tsai Alzheimer's Association International Conference, 2023 | | 2023 |
Apoe4 impairs myelination via altered cholesterol biosynthesis and transport in oligodendroglia J Blanchard, M Kellis, LH Tsai, JD Velderrain, L Akay, D Von Maydell, ... US Patent App. 17/694,630, 2022 | | 2022 |
Probing the functions of microglial cyclin-dependent kinase 5 under physiological and pathological conditions Z Peng, WC Huang, M Chen, J Penney, H Cam, F Abdurrob, L Akay, ... bioRxiv, 2020.05. 12.090605, 2020 | | 2020 |