Massively parallel assessment of human variants with base editor screens RE Hanna, M Hegde, CR Fagre, PC DeWeirdt, AK Sangree, Z Szegletes, ... Cell 184 (4), 1064-1080. e20, 2021 | 229 | 2021 |
Optimization of AsCas12a for combinatorial genetic screens in human cells PC DeWeirdt, KR Sanson, AK Sangree, M Hegde, RE Hanna, MN Feeley, ... Nature biotechnology 39 (1), 94-104, 2021 | 132 | 2021 |
Genetic screens in isogenic mammalian cell lines without single cell cloning PC DeWeirdt, AK Sangree, RE Hanna, KR Sanson, M Hegde, C Strand, ... Nature communications 11 (1), 752, 2020 | 98 | 2020 |
Benchmarking of SpCas9 variants enables deeper base editor screens of BRCA1 and BCL2 AK Sangree, AL Griffith, ZM Szegletes, P Roy, PC DeWeirdt, M Hegde, ... Nature Communications 13 (1), 1318, 2022 | 35 | 2022 |
Discovery of putative tumor suppressors from CRISPR screens reveals rewired lipid metabolism in acute myeloid leukemia cells WF Lenoir, M Morgado, PC DeWeirdt, M McLaughlin, AL Griffith, ... Nature communications 12 (1), 6506, 2021 | 21 | 2021 |
Optimization of AsCas12a for combinatorial genetic screens in human cells KR Sanson, PC DeWeirdt, AK Sangree, RE Hanna, M Hegde, T Teng, ... BioRxiv, 747170, 2019 | 17 | 2019 |
Efficient gene knockout and genetic interaction screening using the in4mer CRISPR/Cas12a multiplex knockout platform N Esmaeili Anvar, C Lin, X Ma, LL Wilson, R Steger, AK Sangree, M Colic, ... Nature Communications 15 (1), 3577, 2024 | 6 | 2024 |
Genetic screens in isogenic mammalian cell lines without single cell cloning. Nat. Commun. 11, 752 PC DeWeirdt, AK Sangree, RE Hanna, KR Sanson, M Hegde, C Strand, ... | 6 | 2020 |
Benchmarking of SpCas9 variants enables deeper base editor screens of BRCA1 and BCL2. Nat. Commun. 13, 1318 AK Sangree, AL Griffith, ZM Szegletes, P Roy, PC DeWeirdt, M Hegde, ... | 5 | 2022 |
Histone 3.3-related chromatinopathy: missense variants throughout H3-3A and H3-3B cause a range of functional consequences across species L Bryant, A Sangree, K Clark, E Bhoj Human Genetics 143 (4), 497-510, 2024 | 4 | 2024 |
Combined genome-scale fitness and paralog synthetic lethality screens with just 44k clones: the IN4MER CRISPR/Cas12a multiplex knockout platform. C Lin, LL Wilson, AK Sangree, X Ma, M Colic, JG Doench, T Hart Biorxiv: the Preprint Server for Biology, 2023 | 4 | 2023 |
Efficient gene knockout and genetic interactions: the IN4MER CRISPR/Cas12a multiplex knockout platform NE Anvar, C Lin, X Ma, LL Wilson, R Steger, AK Sangree, M Colic, ... bioRxiv, 2023 | 2 | 2023 |
Expanded phenotypic spectrum of neurodevelopmental and neurodegenerative disorder Bryant-Li-Bhoj syndrome with 38 additional individuals DE Layo-Carris, EE Lubin, AK Sangree, KJ Clark, EL Durham, ... European Journal of Human Genetics, 1-10, 2024 | | 2024 |
NeuroTri2-VISDOT: An open-access tool to harness the power of second trimester human single cell data to inform models of Mendelian neurodevelopmental disorders KJ Clark, EE Lubin, EM Gonzalez, AK Sangree, DE Layo-Carris, ... bioRxiv, 2024 | | 2024 |
Combining patient phenotypes and transcriptomic data to rationally develop patient models of neurodevelopmental" histonopathies" E Lubin, K Clark, E Gonzalez, A Sangree, L Bryant, D Li, E Bhoj EUROPEAN JOURNAL OF HUMAN GENETICS 32, 203-203, 2024 | | 2024 |
Elucidating the function of H3-3B alternative transcripts in Bryant-Li-Bhoj syndrome A Sangree, R Angireddy, E Gonzalez, E Lubin, K Clark, L Bryant, E Bhoj EUROPEAN JOURNAL OF HUMAN GENETICS 32, 494-495, 2024 | | 2024 |
Abstract SY05-02: Applications of base editor technology in small molecule: Target validation A Griffith, A Sangree, P Roy, R Hanna, J Doench Cancer Research 82 (12_Supplement), SY05-02-SY05-02, 2022 | | 2022 |
Discovery of novel tumor suppressors from CRISPR screens reveals lipid-sensitive subtype of AML WF Lenoir, M Morgado, PC DeWeirdt, M McLaughlin, AL Griffith, ... Hematology. American Society of Hematology. Education Program, 2020 | | 2020 |
Discovery of novel putative tumor suppressors from CRISPR screens reveals rewired lipid metabolism in AML cells WF Lenoir, M Morgado, PC DeWeirdt, M McLaughlin, AL Griffith, ... bioRxiv, 2020.10. 08.332023, 2020 | | 2020 |