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Annabel Sangree
Annabel Sangree
Graduate Student, University of Pennsylvania
在 pennmedicine.upenn.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Massively parallel assessment of human variants with base editor screens
RE Hanna, M Hegde, CR Fagre, PC DeWeirdt, AK Sangree, Z Szegletes, ...
Cell 184 (4), 1064-1080. e20, 2021
2292021
Optimization of AsCas12a for combinatorial genetic screens in human cells
PC DeWeirdt, KR Sanson, AK Sangree, M Hegde, RE Hanna, MN Feeley, ...
Nature biotechnology 39 (1), 94-104, 2021
1322021
Genetic screens in isogenic mammalian cell lines without single cell cloning
PC DeWeirdt, AK Sangree, RE Hanna, KR Sanson, M Hegde, C Strand, ...
Nature communications 11 (1), 752, 2020
982020
Benchmarking of SpCas9 variants enables deeper base editor screens of BRCA1 and BCL2
AK Sangree, AL Griffith, ZM Szegletes, P Roy, PC DeWeirdt, M Hegde, ...
Nature Communications 13 (1), 1318, 2022
352022
Discovery of putative tumor suppressors from CRISPR screens reveals rewired lipid metabolism in acute myeloid leukemia cells
WF Lenoir, M Morgado, PC DeWeirdt, M McLaughlin, AL Griffith, ...
Nature communications 12 (1), 6506, 2021
212021
Optimization of AsCas12a for combinatorial genetic screens in human cells
KR Sanson, PC DeWeirdt, AK Sangree, RE Hanna, M Hegde, T Teng, ...
BioRxiv, 747170, 2019
172019
Efficient gene knockout and genetic interaction screening using the in4mer CRISPR/Cas12a multiplex knockout platform
N Esmaeili Anvar, C Lin, X Ma, LL Wilson, R Steger, AK Sangree, M Colic, ...
Nature Communications 15 (1), 3577, 2024
62024
Genetic screens in isogenic mammalian cell lines without single cell cloning. Nat. Commun. 11, 752
PC DeWeirdt, AK Sangree, RE Hanna, KR Sanson, M Hegde, C Strand, ...
62020
Benchmarking of SpCas9 variants enables deeper base editor screens of BRCA1 and BCL2. Nat. Commun. 13, 1318
AK Sangree, AL Griffith, ZM Szegletes, P Roy, PC DeWeirdt, M Hegde, ...
52022
Histone 3.3-related chromatinopathy: missense variants throughout H3-3A and H3-3B cause a range of functional consequences across species
L Bryant, A Sangree, K Clark, E Bhoj
Human Genetics 143 (4), 497-510, 2024
42024
Combined genome-scale fitness and paralog synthetic lethality screens with just 44k clones: the IN4MER CRISPR/Cas12a multiplex knockout platform.
C Lin, LL Wilson, AK Sangree, X Ma, M Colic, JG Doench, T Hart
Biorxiv: the Preprint Server for Biology, 2023
42023
Efficient gene knockout and genetic interactions: the IN4MER CRISPR/Cas12a multiplex knockout platform
NE Anvar, C Lin, X Ma, LL Wilson, R Steger, AK Sangree, M Colic, ...
bioRxiv, 2023
22023
Expanded phenotypic spectrum of neurodevelopmental and neurodegenerative disorder Bryant-Li-Bhoj syndrome with 38 additional individuals
DE Layo-Carris, EE Lubin, AK Sangree, KJ Clark, EL Durham, ...
European Journal of Human Genetics, 1-10, 2024
2024
NeuroTri2-VISDOT: An open-access tool to harness the power of second trimester human single cell data to inform models of Mendelian neurodevelopmental disorders
KJ Clark, EE Lubin, EM Gonzalez, AK Sangree, DE Layo-Carris, ...
bioRxiv, 2024
2024
Combining patient phenotypes and transcriptomic data to rationally develop patient models of neurodevelopmental" histonopathies"
E Lubin, K Clark, E Gonzalez, A Sangree, L Bryant, D Li, E Bhoj
EUROPEAN JOURNAL OF HUMAN GENETICS 32, 203-203, 2024
2024
Elucidating the function of H3-3B alternative transcripts in Bryant-Li-Bhoj syndrome
A Sangree, R Angireddy, E Gonzalez, E Lubin, K Clark, L Bryant, E Bhoj
EUROPEAN JOURNAL OF HUMAN GENETICS 32, 494-495, 2024
2024
Abstract SY05-02: Applications of base editor technology in small molecule: Target validation
A Griffith, A Sangree, P Roy, R Hanna, J Doench
Cancer Research 82 (12_Supplement), SY05-02-SY05-02, 2022
2022
Discovery of novel tumor suppressors from CRISPR screens reveals lipid-sensitive subtype of AML
WF Lenoir, M Morgado, PC DeWeirdt, M McLaughlin, AL Griffith, ...
Hematology. American Society of Hematology. Education Program, 2020
2020
Discovery of novel putative tumor suppressors from CRISPR screens reveals rewired lipid metabolism in AML cells
WF Lenoir, M Morgado, PC DeWeirdt, M McLaughlin, AL Griffith, ...
bioRxiv, 2020.10. 08.332023, 2020
2020
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