Neurodegenerative diseases and oxidative stress KJ Barnham, CL Masters, AI Bush Nature reviews Drug discovery 3 (3), 205-214, 2004 | 3940 | 2004 |
Treatment with a copper-zinc chelator markedly and rapidly inhibits β-amyloid accumulation in Alzheimer's disease transgenic mice RA Cherny, CS Atwood, ME Xilinas, DN Gray, WD Jones, CA McLean, ... Neuron 30 (3), 665-676, 2001 | 1841 | 2001 |
Alzheimer's disease amyloid-β binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits CC Curtain, F Ali, I Volitakis, RA Cherny, RS Norton, K Beyreuther, ... Journal of Biological Chemistry 276 (23), 20466-20473, 2001 | 835 | 2001 |
Metals in Alzheimer's and Parkinson's diseases KJ Barnham, AI Bush Current opinion in chemical biology 12 (2), 222-228, 2008 | 797 | 2008 |
The redox chemistry of the Alzheimer's disease amyloid β peptide DG Smith, R Cappai, KJ Barnham Biochimica et Biophysica Acta (BBA)-Biomembranes 1768 (8), 1976-1990, 2007 | 793 | 2007 |
Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease JA Duce, A Tsatsanis, MA Cater, SA James, E Robb, K Wikhe, SL Leong, ... Cell 142 (6), 857-867, 2010 | 789 | 2010 |
Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Aβ PA Adlard, RA Cherny, DI Finkelstein, E Gautier, E Robb, M Cortes, ... Neuron 59 (1), 43-55, 2008 | 781 | 2008 |
Biological metals and metal-targeting compounds in major neurodegenerative diseases KJ Barnham, AI Bush Chemical Society Reviews 43 (19), 6727-6749, 2014 | 485 | 2014 |
Cisplatin binding sites on human albumin AI Ivanov, J Christodoulou, JA Parkinson, KJ Barnham, A Tucker, ... Journal of Biological Chemistry 273 (24), 14721-14730, 1998 | 467 | 1998 |
18F-THK523: a novel in vivo tau imaging ligand for Alzheimer’s disease MT Fodero-Tavoletti, N Okamura, S Furumoto, RS Mulligan, AR Connor, ... Brain 134 (4), 1089-1100, 2011 | 398 | 2011 |
Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-β1-42 PJ Crouch, R Blake, JA Duce, GD Ciccotosto, QX Li, KJ Barnham, ... Journal of Neuroscience 25 (3), 672-679, 2005 | 398 | 2005 |
Structure of the Alzheimer's disease amyloid precursor protein copper binding domain: a regulator of neuronal copper homeostasis KJ Barnham, WJ McKinstry, G Multhaup, D Galatis, CJ Morton, CC Curtain, ... Journal of Biological Chemistry 278 (19), 17401-17407, 2003 | 378 | 2003 |
Degradation of the Alzheimer disease amyloid β-peptide by metal-dependent up-regulation of metalloprotease activity AR White, T Du, KM Laughton, I Volitakis, RA Sharples, ME Xilinas, ... Journal of Biological Chemistry 281 (26), 17670-17680, 2006 | 352 | 2006 |
Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106− 126 MF Jobling, X Huang, LR Stewart, KJ Barnham, C Curtain, I Volitakis, ... Biochemistry 40 (27), 8073-8084, 2001 | 328 | 2001 |
Dopamine promotes α‐synuclein aggregation into SDS‐resistant soluble oligomers via a distinct folding pathway R Cappai, SL Leck, DJ Tew, NA Williamson, DP Smith, D Galatis, ... The FASEB journal 19 (10), 1377-1379, 2005 | 324 | 2005 |
Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease β‐amyloid KJ Barnham, F Haeffner, GD Ciccotosto, CC Curtain, D Tew, C Mavros, ... The FASEB Journal 18 (12), 1427-1429, 2004 | 314 | 2004 |
Increasing Cu bioavailability inhibits Aβ oligomers and tau phosphorylation PJ Crouch, LW Hung, PA Adlard, M Cortes, V Lal, G Filiz, KA Perez, ... Proceedings of the National Academy of Sciences 106 (2), 381-386, 2009 | 312 | 2009 |
Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics CL Masters, R Cappai, KJ Barnham, VL Villemagne Journal of neurochemistry 97 (6), 1700-1725, 2006 | 300 | 2006 |
Pleomorphic copper coordination by Alzheimer’s disease amyloid-β peptide SC Drew, CJ Noble, CL Masters, GR Hanson, KJ Barnham Journal of the American Chemical Society 131 (3), 1195-1207, 2009 | 274 | 2009 |
Inhibition of γ‐secretase causes increased secretion of amyloid precursor protein C‐terminal fragments in association with exosomes RA Sharples, LJ Vella, RM Nisbet, R Naylor, K Perez, KJ Barnham, ... The FASEB Journal 22 (5), 1469-1478, 2008 | 270 | 2008 |