Comprehensive genomic profiles of small cell lung cancer J George, JS Lim, SJ Jang, Y Cun, L Ozretić, G Kong, F Leenders, X Lu, ... Nature 524 (7563), 47-53, 2015 | 2035 | 2015 |
CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer K Weiskopf, NS Jahchan, PJ Schnorr, S Cristea, AM Ring, RL Maute, ... The Journal of clinical investigation 126 (7), 2610-2620, 2016 | 404 | 2016 |
Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer JS Lim, A Ibaseta, MM Fischer, B Cancilla, G O’Young, S Cristea, VC Luca, ... Nature 545 (7654), 360-364, 2017 | 393 | 2017 |
A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors NS Jahchan, JT Dudley, PK Mazur, N Flores, D Yang, A Palmerton, ... Cancer discovery 3 (12), 1364-1377, 2013 | 388 | 2013 |
A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis N He, NS Jahchan, E Hong, Q Li, MA Bayfield, RJ Maraia, K Luo, Q Zhou Molecular cell 29 (5), 588-599, 2008 | 283 | 2008 |
Targeting TREM2 on tumor-associated macrophages enhances immunotherapy M Binnewies, JL Pollack, J Rudolph, S Dash, M Abushawish, T Lee, ... Cell reports 37 (3), 2021 | 167 | 2021 |
Phosphorylation and activation of PINOID by the phospholipid signaling kinase 3-phosphoinositide-dependent protein kinase 1 (PDK1) in Arabidopsis H Zegzouti, RG Anthony, N Jahchan, L Bögre, SK Christensen Proceedings of the National Academy of Sciences 103 (16), 6404-6409, 2006 | 161 | 2006 |
Intertumoral heterogeneity in SCLC is influenced by the cell type of origin D Yang, SK Denny, PG Greenside, AC Chaikovsky, JJ Brady, Y Ouadah, ... Cancer discovery 8 (10), 1316-1331, 2018 | 130 | 2018 |
Are there multiple cells of origin of Merkel cell carcinoma? JC Sunshine, NS Jahchan, J Sage, J Choi Oncogene 37 (11), 1409-1416, 2018 | 121 | 2018 |
Tuning the tumor myeloid microenvironment to fight cancer NS Jahchan, AM Mujal, JL Pollack, M Binnewies, V Sriram, L Reyno, ... Frontiers in Immunology 10, 1611, 2019 | 106 | 2019 |
Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors GW Krampitz, BM George, SB Willingham, JP Volkmer, K Weiskopf, ... Proceedings of the National Academy of Sciences 113 (16), 4464-4469, 2016 | 96 | 2016 |
Identification and targeting of long-term tumor-propagating cells in small cell lung cancer NS Jahchan, JS Lim, B Bola, K Morris, G Seitz, KQ Tran, L Xu, F Trapani, ... Cell reports 16 (3), 644-656, 2016 | 89 | 2016 |
Genomic analysis of fibrolamellar hepatocellular carcinoma L Xu, FK Hazard, AF Zmoos, N Jahchan, H Chaib, PM Garfin, ... Human molecular genetics 24 (1), 50-63, 2015 | 82 | 2015 |
Axon-like protrusions promote small cell lung cancer migration and metastasis D Yang, F Qu, H Cai, CH Chuang, JS Lim, N Jahchan, BM Grüner, ... Elife 8, e50616, 2019 | 47 | 2019 |
SnoN in mammalian development, function and diseases NS Jahchan, K Luo Current Opinion in Pharmacology 10 (6), 670-675, 2010 | 46 | 2010 |
SnoN antagonizes the Hippo kinase complex to promote TAZ signaling during breast carcinogenesis Q Zhu, E Le Scolan, N Jahchan, X Ji, A Xu, K Luo Developmental cell 37 (5), 399-412, 2016 | 37 | 2016 |
SnoN regulates mammary gland alveologenesis and onset of lactation by promoting prolactin/Stat5 signaling NS Jahchan, D Wang, MJ Bissell, K Luo Development 139 (17), 3147-3156, 2012 | 33 | 2012 |
Transforming growth factor-β regulator SnoN modulates mammary gland branching morphogenesis, postlactational involution, and mammary tumorigenesis NS Jahchan, YH You, WJ Muller, K Luo Cancer research 70 (10), 4204-4213, 2010 | 30 | 2010 |
Discovery of a potent and selective steroidal glucocorticoid receptor antagonist (ORIC-101) Y Rew, X Du, J Eksterowicz, H Zhou, N Jahchan, L Zhu, X Yan, H Kawai, ... Journal of Medicinal Chemistry 61 (17), 7767-7784, 2018 | 28 | 2018 |
Expression profiles of SnoN in normal and cancerous human tissues support its tumor suppressor role in human cancer NS Jahchan, G Ouyang, K Luo PloS one 8 (2), e55794, 2013 | 20 | 2013 |