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John-Demian Sauer
John-Demian Sauer
Associate Professor University of Wisconsin, Department of Medical Microbiology and Immunology
在 wisc.edu 的电子邮件经过验证 - 首页
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The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic …
JD Sauer, K Sotelo-Troha, J Von Moltke, KM Monroe, CS Rae, ...
Infection and immunity 79 (2), 688-694, 2011
6322011
Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol
JD Sauer, CE Witte, J Zemansky, B Hanson, P Lauer, DA Portnoy
Cell host & microbe 7 (5), 412-419, 2010
3642010
The cyclic dinucleotide c-di-AMP is an allosteric regulator of metabolic enzyme function
K Sureka, PH Choi, M Precit, M Delince, DA Pensinger, TAN Huynh, ...
Cell 158 (6), 1389-1401, 2014
2262014
An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence
TAN Huynh, S Luo, D Pensinger, JD Sauer, L Tong, JJ Woodward
Proceedings of the National Academy of Sciences 112 (7), E747-E756, 2015
2082015
Cyclic di-AMP is critical for Listeria monocytogenes growth, cell wall homeostasis, and establishment of infection
CE Witte, AT Whiteley, TP Burke, JD Sauer, DA Portnoy, JJ Woodward
MBio 4 (3), 10.1128/mbio. 00282-13, 2013
2072013
Type I IFN signaling constrains IL-17A/F secretion by γδ T cells during bacterial infections
T Henry, GS Kirimanjeswara, T Ruby, JW Jones, K Peng, M Perret, L Ho, ...
The Journal of Immunology 184 (7), 3755-3767, 2010
1872010
Broad detection of bacterial type III secretion system and flagellin proteins by the human NAIP/NLRC4 inflammasome
VM Reyes Ruiz, J Ramirez, N Naseer, NM Palacio, IJ Siddarthan, BM Yan, ...
Proceedings of the National Academy of Sciences 114 (50), 13242-13247, 2017
1632017
Differential requirements for NAIP5 in activation of the NLRC4 inflammasome
KL Lightfield, J Persson, NJ Trinidad, SW Brubaker, EM Kofoed, JD Sauer, ...
Infection and immunity 79 (4), 1606-1614, 2011
1582011
The phagosomal transporter A couples threonine acquisition to differentiation and replication of Legionella pneumophila in macrophages
JD Sauer, MA Bachman, MS Swanson
Proceedings of the National Academy of Sciences 102 (28), 9924-9929, 2005
1562005
Listeria monocytogenes engineered to activate the Nlrc4 inflammasome are severely attenuated and are poor inducers of protective immunity
JD Sauer, S Pereyre, KA Archer, TP Burke, B Hanson, P Lauer, ...
Proceedings of the National Academy of Sciences 108 (30), 12419-12424, 2011
1482011
Innate immune pathways triggered by Listeria monocytogenes and their role in the induction of cell-mediated immunity
CE Witte, KA Archer, CS Rae, JD Sauer, JJ Woodward, DA Portnoy
Advances in immunology 113, 135-156, 2012
1172012
Macrophages mediate flagellin induced inflammasome activation and host defense in zebrafish
WJB Vincent, CM Freisinger, P Lam, A Huttenlocher, JD Sauer
Cellular microbiology 18 (4), 591-604, 2016
812016
Distinct inflammatory and wound healing responses to complex caudal fin injuries of larval zebrafish
V Miskolci, J Squirrell, J Rindy, W Vincent, JD Sauer, A Gibson, ...
Elife 8, e45976, 2019
732019
The Listeria monocytogenes PASTA Kinase PrkA and Its Substrate YvcK Are Required for Cell Wall Homeostasis, Metabolism, and Virulence
DA Pensinger, KM Boldon, GY Chen, WJB Vincent, K Sherman, M Xiong, ...
PLoS pathogens 12 (11), e1006001, 2016
702016
Specificity of Legionella pneumophila and Coxiella burnetii Vacuoles and Versatility of Legionella pneumophila Revealed by Coinfection
JD Sauer, JG Shannon, D Howe, SF Hayes, MS Swanson, RA Heinzen
Infection and immunity 73 (8), 4494-4504, 2005
632005
Penicillin binding protein 1 is important in the compensatory response of Staphylococcus aureus to daptomycin-induced membrane damage and is a potential target for β-lactam …
AD Berti, E Theisen, JD Sauer, P Nonejuie, J Olson, J Pogliano, ...
Antimicrobial agents and chemotherapy 60 (1), 451-458, 2016
622016
Selective pharmacologic inhibition of a PASTA kinase increases Listeria monocytogenes susceptibility to β-lactam antibiotics
DA Pensinger, MT Aliota, AJ Schaenzer, KM Boldon, IH Ansari, ...
Antimicrobial agents and chemotherapy 58 (8), 4486-4494, 2014
622014
Do shoot the messenger: PASTA kinases as virulence determinants and antibiotic targets
DA Pensinger, AJ Schaenzer, JD Sauer
Trends in microbiology 26 (1), 56-69, 2018
612018
NAD (H)-loaded nanoparticles for efficient sepsis therapy via modulating immune and vascular homeostasis
M Ye, Y Zhao, Y Wang, R Xie, Y Tong, JD Sauer, S Gong
Nature nanotechnology 17 (8), 880-890, 2022
562022
The phagosomal nutrient transporter (Pht) family
DE Chen, S Podell, JD Sauer, MS Swanson, MH Saier
Microbiology 154 (1), 42-53, 2008
502008
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