A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency J Tordo, C O’Leary, ASLM Antunes, N Palomar, P Aldrin-Kirk, M Basche, ... Brain 141 (7), 2014-2031, 2018 | 103 | 2018 |
Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: a putative model of gene× environment interaction L Desbonnet, C O’Tuathaigh, G Clarke, C O’Leary, E Petit, N Clarke, ... Brain, behavior, and immunity 26 (4), 660-671, 2012 | 98 | 2012 |
Schizophrenia‐related endophenotypes in heterozygous neuregulin‐1 ‘knockout’mice CMP O’Tuathaigh, M Harte, C O’Leary, GJ O’Sullivan, C Blau, D Lai, ... European journal of neuroscience 31 (2), 349-358, 2010 | 83 | 2010 |
Phenotypic effects of maternal immune activation and early postnatal milieu in mice mutant for the schizophrenia risk gene neuregulin-1 C O’Leary, L Desbonnet, N Clarke, E Petit, O Tighe, D Lai, R Harvey, ... Neuroscience 277, 294-305, 2014 | 82 | 2014 |
Brain‐targeted stem cell gene therapy corrects mucopolysaccharidosis type II via multiple mechanisms HFE Gleitz, AY Liao, JR Cook, SF Rowlston, GMA Forte, Z D'souza, ... EMBO molecular medicine 10 (7), e8730, 2018 | 81 | 2018 |
Macrophage enzyme and reduced inflammation drive brain correction of mucopolysaccharidosis IIIB by stem cell gene therapy RJ Holley, SM Ellison, D Fil, C O’Leary, J McDermott, N Senthivel, ... Brain 141 (1), 99-116, 2018 | 74 | 2018 |
Genetic vs. pharmacological inactivation of COMT influences cannabinoid-induced expression of schizophrenia-related phenotypes CMP O'Tuathaigh, G Clarke, J Walsh, L Desbonnet, E Petit, C O'Leary, ... International Journal of Neuropsychopharmacology 15 (9), 1331-1342, 2012 | 66 | 2012 |
The inflammatory microenvironment in vestibular schwannoma CJ Hannan, D Lewis, C O’leary, CA Donofrio, DG Evans, F Roncaroli, ... Neuro-Oncology Advances 2 (1), vdaa023, 2020 | 61 | 2020 |
Anakinra in COVID-19: important considerations for clinical trials A King, A Vail, C O'Leary, C Hannan, D Brough, H Patel, J Galea, ... The Lancet Rheumatology 2 (7), e379-e381, 2020 | 53 | 2020 |
Haematopoietic stem cell gene therapy with IL‐1Ra rescues cognitive loss in mucopolysaccharidosis IIIA H Parker, SM Ellison, RJ Holley, C O'Leary, A Liao, J Asadi, E Glover, ... EMBO Molecular Medicine 12 (3), e11185, 2020 | 36 | 2020 |
High dose genistein in Sanfilippo syndrome: A randomised controlled trial A Ghosh, S Rust, K Langford‐Smith, D Weisberg, M Canal, C Breen, ... Journal of Inherited Metabolic Disease 44 (5), 1248-1262, 2021 | 28 | 2021 |
Identification of age-dependent motor and neuropsychological behavioural abnormalities in a mouse model of Mucopolysaccharidosis Type II HFE Gleitz, C O’Leary, RJ Holley, BW Bigger PLoS One 12 (2), e0172435, 2017 | 27 | 2017 |
The microenvironment in sporadic and neurofibromatosis type II–related vestibular schwannoma: the same tumor or different? A comparative imaging and neuropathology study D Lewis, CA Donofrio, C O’Leary, K Li, X Zhu, R Williams, I Djoukhadar, ... Journal of neurosurgery 134 (5), 1419-1429, 2020 | 25 | 2020 |
A nonmyeloablative chimeric mouse model accurately defines microglia and macrophage contribution in glioma K Yu, AS Youshani, FL Wilkinson, C O'Leary, P Cook, L Laaniste, A Liao, ... Neuropathology and applied neurobiology 45 (2), 119-140, 2019 | 25 | 2019 |
Neuronal glycosylation differentials in normal, injured and chondroitinase-treated environments M Kilcoyne, S Sharma, N McDevitt, C O’Leary, L Joshi, SS McMahon Biochemical and biophysical research communications 420 (3), 616-622, 2012 | 25 | 2012 |
Non-myeloablative busulfan chimeric mouse models are less pro-inflammatory than head-shielded irradiation for studying immune cell interactions in brain tumours AS Youshani, S Rowlston, C O’Leary, G Forte, H Parker, A Liao, B Telfer, ... Journal of Neuroinflammation 16, 1-14, 2019 | 24 | 2019 |
Epistatic and independent effects on schizophrenia-related phenotypes following co-disruption of the risk factors Neuregulin-1× DISC1 CMP O’Tuathaigh, F Fumagalli, L Desbonnet, F Perez-Branguli, ... Schizophrenia Bulletin 43 (1), 214-225, 2017 | 19 | 2017 |
Resolving pathobiological mechanisms relating to Huntington disease: gait, balance, and involuntary movements in mice with targeted ablation of striatal D1 dopamine receptor cells HA Kim, L Jiang, H Madsen, CL Parish, J Massalas, A Smardencas, ... Neurobiology of disease 62, 323-337, 2014 | 19 | 2014 |
The spatial phenotype of genotypically distinct meningiomas demonstrate potential implications of the embryology of the meninges DM Fountain, MJ Smith, C O’Leary, ON Pathmanaban, F Roncaroli, ... Oncogene 40 (5), 875-884, 2021 | 18 | 2021 |
An improved adeno-associated virus vector for neurological correction of the mouse model of mucopolysaccharidosis IIIA AL Gray, C O'Leary, A Liao, L Agúndez, AS Youshani, HF Gleitz, H Parker, ... Human Gene Therapy 30 (9), 1052-1066, 2019 | 17 | 2019 |