Transcription facilitated genome-wide recruitment of topoisomerase I and DNA gyrase W Ahmed, C Sala, SR Hegde, RK Jha, ST Cole, V Nagaraja PLoS Genetics 13 (5), e1006754, 2017 | 60 | 2017 |
Efficacy of β-lactam/β-lactamase inhibitor combination is linked to WhiB4-mediated changes in redox physiology of Mycobacterium tuberculosis S Mishra, P Shukla, A Bhaskar, K Anand, P Baloni, RK Jha, A Mohan, ... Elife 6, e25624, 2017 | 54 | 2017 |
MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome” SK Das, V Kuzin, DP Cameron, S Sanford, RK Jha, Z Nie, MT Rosello, ... Molecular cell 82 (1), 140-158. e12, 2022 | 42 | 2022 |
Physical and functional interaction between nucleoid‐associated proteins HU and Lsr2 of Mycobacterium tuberculosis: altered DNA binding and gene regulation C Datta, RK Jha, W Ahmed, S Ganguly, S Ghosh, V Nagaraja Molecular Microbiology 111 (4), 981-994, 2019 | 27 | 2019 |
Mechanical determinants of chromatin topology and gene expression RK Jha, D Levens, F Kouzine Nucleus 13 (1), 95-116, 2022 | 23 | 2022 |
Mycobacterium tuberculosis SufR responds to nitric oxide via its 4Fe–4S cluster and regulates Fe–S cluster biogenesis for persistence in mice K Anand, A Tripathi, K Shukla, N Malhotra, AK Jamithireddy, RK Jha, ... Redox Biology 46, 102062, 2021 | 16 | 2021 |
NapA (Rv0430), a novel nucleoid-associated protein that regulates a virulence operon in Mycobacterium tuberculosis in a supercoiling-dependent manner C Datta, RK Jha, S Ganguly, V Nagaraja Journal of molecular biology 431 (8), 1576-1591, 2019 | 15 | 2019 |
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase G Mori, BS Orena, C Franch, LA Mitchenall, AA Godbole, L Rodrigues, ... Tuberculosis 112, 98-109, 2018 | 14 | 2018 |
A Type IA DNA/RNA topoisomerase with RNA hydrolysis activity participates in ribosomal RNA processing P Rani, SM Kalladi, H Bansia, S Rao, RK Jha, P Jain, T Bhaduri, ... Journal of molecular biology 432 (20), 5614-5631, 2020 | 8 | 2020 |
Conditional down-regulation of GreA impacts expression of rRNA and transcription factors, affecting Mycobacterium smegmatis survival RK Jha, S Udupa, AK Rai, P Rani, PR Singh, S Govind, V Nagaraja Scientific Reports 10 (1), 5802, 2020 | 8 | 2020 |
DNA flowerstructure co-localizes with human pathogens in infected macrophages O Franch, C Gutiérrez-Corbo, B Domínguez-Asenjo, T Boesen, ... Nucleic Acids Research 48 (11), 6081-6091, 2020 | 7 | 2020 |
MYC function and regulation in physiological perspective RK Jha, F Kouzine, D Levens Frontiers in Cell and Developmental Biology 11, 1268275, 2023 | 6 | 2023 |
Self-assembly of promoter DNA and RNA Pol II machinery into transcriptionally active biomolecular condensates BA Lewis, SK Das, RK Jha, D Levens Science Advances 9 (42), eadi4565, 2023 | 6 | 2023 |
Regulation of the gyr operon of Mycobacterium tuberculosis by overlapping promoters, DNA topology, and reiterative transcription RK Jha, P Tare, V Nagaraja Biochemical and biophysical research communications 501 (4), 877-884, 2018 | 4 | 2018 |
Discovery of Anthranilic Acid Derivatives as Difluoromethylornithine Adjunct Agents That Inhibit Far Upstream Element Binding Protein 1 (FUBP1) Function A Dobrovolskaite, H Moots, MP Tantak, K Shah, J Thomas, S Dinara, ... Journal of medicinal chemistry 65 (22), 15391-15415, 2022 | 2 | 2022 |
The Roles of DNA Structure and DNA Topology at MYC, with MYC and Across the Genome. D Levens, F Kouzine, Y Zhang, L Baranello, Z Nie, SK Das, R Jha, ... ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 61, 47-48, 2020 | | 2020 |
A multifunctional type IA DNA/RNA topoisomerase with RNA hydrolysis and rRNA processing activities fromMycobacterium smegmatisandMycobacterium tuberculosis P Rani, SM Kalladi, H Bansia, S Rao, RK Jha, P Jain, T Bhaduri, ... | | 2020 |
A multifunctional Type1A DNA/RNA topoisomerase with RNA hydrolysis activity from Mycobacterium smegmatis and Mycobacterium tuberculosis P Rani, SM Kalladi, H Bansia, S Rao, RK Jha, P Jain, T Bhaduri, ... bioRxiv, 2020.07. 13.199935, 2020 | | 2020 |
Nitric oxide-inducible Fe-S cluster biogenesis enables Mycobacterium tuberculosis to persist in mice K Anand, A Tripathi, K Shukla, N Malhotra, A Jamithireddy, RK Jha, ... bioRxiv, 2020 | | 2020 |
Insights into the Regulation of Transcription Initiation of DNA Gyrase and Role of Transcription Factor Gre from Mycobacterium tuberculosis RK Jha | | 2018 |