| The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease JM Shillingford, NS Murcia, CH Larson, SH Low, R Hedgepeth, N Brown, ... Proceedings of the National Academy of Sciences 103 (14), 5466-5471, 2006 | 982 | 2006 |
| Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium K Miyoshi, JM Shillingford, GH Smith, SL Grimm, KU Wagner, T Oka, ... The Journal of cell biology 155 (4), 531-542, 2001 | 344 | 2001 |
| Rapamycin ameliorates PKD resulting from conditional inactivation of Pkd1 JM Shillingford, KB Piontek, GG Germino, T Weimbs Journal of the American Society of Nephrology 21 (3), 489-497, 2010 | 310 | 2010 |
| Acute Myeloid Leukemia-Associated Mkl1 (Mrtf-a) Is a Key Regulator of Mammary Gland Function Y Sun, K Boyd, W Xu, J Ma, CW Jackson, A Fu, JM Shillingford, ... Molecular and cellular biology 26 (15), 5809-5826, 2006 | 206 | 2006 |
| Impaired differentiation and lactational failure of Erbb4-deficient mammary glands identify ERBB4 as an obligate mediator of STAT5 W Long, KU Wagner, KCK Lloyd, N Binart, JM Shillingford, ... Oxford University Press for The Company of Biologists Limited 130 (21), 5257 …, 2003 | 197 | 2003 |
| Activation of β-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation B Bierie, M Nozawa, JP Renou, JM Shillingford, F Morgan, T Oka, ... Oncogene 22 (25), 3875-3887, 2003 | 164 | 2003 |
| Polycystin-1 regulates STAT activity by a dual mechanism JJ Talbot, JM Shillingford, S Vasanth, N Doerr, S Mukherjee, MT Kinter, ... Proceedings of the National Academy of Sciences 108 (19), 7985-7990, 2011 | 158 | 2011 |
| Activation of β-catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias K Miyoshi, JM Shillingford, F Le Provost, F Gounari, R Bronson, ... Proceedings of the National Academy of Sciences 99 (1), 219-224, 2002 | 156 | 2002 |
| Folate-conjugated rapamycin slows progression of polycystic kidney disease JM Shillingford, CP Leamon, IR Vlahov, T Weimbs Journal of the American Society of Nephrology 23 (10), 1674-1681, 2012 | 127 | 2012 |
| Jak2 is an essential tyrosine kinase involved in pregnancy-mediated development of mammary secretory epithelium JM Shillingford, K Miyoshi, GW Robinson, SL Grimm, JM Rosen, ... Molecular endocrinology 16 (3), 563-570, 2002 | 104 | 2002 |
| Signal transducer and activator of transcription-6 (STAT6) inhibition suppresses renal cyst growth in polycystic kidney disease EE Olsan, S Mukherjee, B Wulkersdorfer, JM Shillingford, AJ Giovannone, ... Proceedings of the National Academy of Sciences 108 (44), 18067-18072, 2011 | 92 | 2011 |
| Conditional deletion of the bcl-x gene from mouse mammary epithelium results in accelerated apoptosis during involution but does not compromise cell function during lactation KD Walton, KU Wagner, EB Rucker III, JM Shillingford, K Miyoshi, ... Mechanisms of development 109 (2), 281-293, 2001 | 92 | 2001 |
| Development of the mammary gland requires DGAT1 expression in stromal and epithelial tissues S Cases, P Zhou, JM Shillingford, BS Wiseman, JD Fish, CS Angle, ... Oxford University Press for The Company of Biologists Limited 131 (13), 3047 …, 2004 | 67 | 2004 |
| Proteotyping of mammary tissue from transgenic and gene knockout mice with immunohistochemical markers: a tool to define developmental lesions JM Shillingford, K Miyoshi, GW Robinson, B Bierie, Y Cao, M Karin, ... Journal of Histochemistry & Cytochemistry 51 (5), 555-565, 2003 | 60 | 2003 |
| Mouse mammary epithelial cells express the Na-K-Cl cotransporter, NKCC1: characterization, localization, and involvement in ductal development and morphogenesis JM Shillingford, K Miyoshi, M Flagella, GE Shull, L Hennighausen Molecular endocrinology 16 (6), 1309-1321, 2002 | 56 | 2002 |
| Emerging targeted strategies for the treatment of autosomal dominant polycystic kidney disease T Weimbs, JM Shillingford, J Torres, SL Kruger, BC Bourgeois Clinical kidney journal 11 (suppl_1), i27-i38, 2018 | 44 | 2018 |
| Experimental mouse genetics–answering fundamental questions about mammary gland biology JM Shillingford, L Hennighausen Trends in Endocrinology & Metabolism 12 (9), 402-408, 2001 | 43 | 2001 |
| Comparison of folate-conjugated rapamycin versus unconjugated rapamycin in an orthologous mouse model of polycystic kidney disease KR Kipp, SL Kruger, MF Schimmel, N Parker, JM Shillingford, CP Leamon, ... American Journal of Physiology-Renal Physiology 315 (2), F395-F405, 2018 | 32 | 2018 |
| Inhibition of lysosomal phospholipase A2 predicts drug-induced phospholipidosis V Hinkovska-Galcheva, T Treadwell, JM Shillingford, A Lee, A Abe, ... Journal of lipid research 62, 2021 | 26 | 2021 |
| Rapamycin‐mediated suppression of renal cyst expansion in del34 Pkd1−/− mutant mouse embryos: An investigation of the feasibility of renal cyst prevention in … C Stayner, J Shields, L Slobbe, JM Shillingford, T Weimbs, MR Eccles Nephrology 17 (8), 739-747, 2012 | 18 | 2012 |
Lothar HennighausenNational Institutes of Health在 mail.nih.gov 的电子邮件经过验证
