TGF-β family signaling in the control of cell proliferation and survival Y Zhang, PB Alexander, XF Wang Cold Spring Harbor perspectives in biology 9 (4), a022145, 2017 | 590 | 2017 |
Dependence of mouse embryonic stem cells on threonine catabolism J Wang, P Alexander, L Wu, R Hammer, O Cleaver, SL McKnight Science 325 (5939), 435-439, 2009 | 406 | 2009 |
Local mutational diversity drives intratumoral immune heterogeneity in non-small cell lung cancer Q Jia, W Wu, Y Wang, PB Alexander, C Sun, Z Gong, JN Cheng, H Sun, ... Nature communications 9 (1), 5361, 2018 | 380 | 2018 |
Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cells L Zhao, R He, H Long, B Guo, Q Jia, D Qin, SQ Liu, Z Wang, T Xiang, ... Nature medicine 24 (10), 1536-1544, 2018 | 143 | 2018 |
Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression D Huang, Y Wang, JW Thompson, T Yin, PB Alexander, D Qin, P Mudgal, ... Nature cell biology 24 (2), 230-241, 2022 | 127 | 2022 |
Rad17 recruits the MRE 11‐RAD 50‐NBS 1 complex to regulate the cellular response to DNA double‐strand breaks Q Wang, M Goldstein, P Alexander, TP Wakeman, T Sun, J Feng, Z Lou, ... The EMBO journal 33 (8), 862-877, 2014 | 119 | 2014 |
Tumor-induced erythroid precursor-differentiated myeloid cells mediate immunosuppression and curtail anti-PD-1/PD-L1 treatment efficacy H Long, Q Jia, L Wang, W Fang, Z Wang, T Jiang, F Zhou, Z Jin, J Huang, ... Cancer cell 40 (6), 674-693. e7, 2022 | 78 | 2022 |
MiR-148a functions to suppress metastasis and serves as a prognostic indicator in triple-negative breast cancer X Xu, Y Zhang, J Jasper, E Lykken, PB Alexander, GJ Markowitz, ... Oncotarget 7 (15), 20381, 2016 | 71 | 2016 |
EGF promotes mammalian cell growth by suppressing cellular senescence PB Alexander, L Yuan, P Yang, T Sun, R Chen, H Xiang, J Chen, H Wu, ... Cell research 25 (1), 135-138, 2015 | 69 | 2015 |
Targeted killing of a mammalian cell based upon its specialized metabolic state PB Alexander, J Wang, SL McKnight Proceedings of the National Academy of Sciences 108 (38), 15828-15833, 2011 | 62 | 2011 |
CD 36 initiates the secretory phenotype during the establishment of cellular senescence M Chong, T Yin, R Chen, H Xiang, L Yuan, Y Ding, CC Pan, Z Tang, ... EMBO reports 19 (6), e45274, 2018 | 61 | 2018 |
Resistance to receptor tyrosine kinase inhibition in cancer: molecular mechanisms and therapeutic strategies PB Alexander, XF Wang Frontiers of medicine 9, 134-138, 2015 | 57 | 2015 |
Radiation-induced eosinophils improve cytotoxic T lymphocyte recruitment and response to immunotherapy JN Cheng, W Luo, C Sun, Z Jin, X Zeng, PB Alexander, Z Gong, X Xia, ... Science advances 7 (5), eabc7609, 2021 | 51 | 2021 |
Metabolic specialization of mouse embryonic stem cells J Wang, P Alexander, SL McKnight Cold Spring Harbor symposia on quantitative biology 76, 183-193, 2011 | 50 | 2011 |
Distinct receptor tyrosine kinase subsets mediate anti-HER2 drug resistance in breast cancer PB Alexander, R Chen, C Gong, L Yuan, JS Jasper, Y Ding, GJ Markowitz, ... Journal of Biological Chemistry 292 (2), 748-759, 2017 | 41 | 2017 |
Cellular senescence: from anti-cancer weapon to anti-aging target L Yuan, PB Alexander, XF Wang Science China Life Sciences 63 (3), 332-342, 2020 | 35 | 2020 |
UHRF1 is required for basal stem cell proliferation in response to airway injury H Xiang, L Yuan, X Gao, PB Alexander, O Lopez, C Lau, Y Ding, M Chong, ... Cell discovery 3 (1), 1-15, 2017 | 35 | 2017 |
SECTM1 produced by tumor cells attracts human monocytes via CD7-mediated activation of the PI3K pathway T Wang, Y Ge, M Xiao, A Lopez-Coral, L Li, A Roesch, C Huang, ... Journal of Investigative Dermatology 134 (4), 1108-1118, 2014 | 34 | 2014 |
GABAergic signaling beyond synapses: an emerging target for cancer therapy D Huang, PB Alexander, QJ Li, XF Wang Trends in cell biology 33 (5), 403-412, 2023 | 30 | 2023 |
Potential lung attack and lethality generated by EpCAM-specific CAR-T cells in immunocompetent mouse models D Qin, D Li, B Zhang, Y Chen, X Liao, X Li, PB Alexander, Y Wang, QJ Li Oncoimmunology 9 (1), 1806009, 2020 | 30 | 2020 |