G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy E Ruggiero, SN Richter Nucleic acids research 46 (7), 3270-3283, 2018 | 396 | 2018 |
A dynamic G-quadruplex region regulates the HIV-1 long terminal repeat promoter R Perrone, M Nadai, I Frasson, JA Poe, E Butovskaya, TE Smithgall, ... Journal of medicinal chemistry 56 (16), 6521-6530, 2013 | 192 | 2013 |
Quinone methides tethered to naphthalene diimides as selective G-quadruplex alkylating agents M Di Antonio, F Doria, SN Richter, C Bertipaglia, M Mella, C Sissi, ... Journal of the American Chemical Society 131 (36), 13132-13141, 2009 | 171 | 2009 |
Nucleolin stabilizes G-quadruplex structures folded by the LTR promoter and silences HIV-1 viral transcription E Tosoni, I Frasson, M Scalabrin, R Perrone, E Butovskaya, M Nadai, ... Nucleic acids research 43 (18), 8884-8897, 2015 | 157 | 2015 |
The Herpes Simplex Virus-1 genome contains multiple clusters of repeated G-quadruplex: Implications for the antiviral activity of a G-quadruplex ligand S Artusi, M Nadai, R Perrone, MA Biasolo, G Palu, L Flamand, A Calistri, ... Antiviral research 118, 123-131, 2015 | 148 | 2015 |
Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome S Lago, M Nadai, FM Cernilogar, M Kazerani, H Domíniguez Moreno, ... Nature communications 12 (1), 3885, 2021 | 144 | 2021 |
Anti-HIV-1 activity of the G-quadruplex ligand BRACO-19 R Perrone, E Butovskaya, D Daelemans, G Palu, C Pannecouque, ... Journal of antimicrobial chemotherapy 69 (12), 3248-3258, 2014 | 144 | 2014 |
Binol quinone methides as bisalkylating and DNA cross-linking agents SN Richter, S Maggi, SC Mels, M Palumbo, M Freccero Journal of the American Chemical Society 126 (43), 13973-13979, 2004 | 139 | 2004 |
G-quadruplex forming sequences in the genome of all known human viruses: A comprehensive guide E Lavezzo, M Berselli, I Frasson, R Perrone, G Palù, AR Brazzale, ... PLoS computational biology 14 (12), e1006675, 2018 | 131 | 2018 |
TAR RNA loop: a scaffold for the assembly of a regulatory switch in HIV replication S Richter, YH Ping, TM Rana Proceedings of the National Academy of Sciences 99 (12), 7928-7933, 2002 | 129 | 2002 |
Formation of a unique cluster of G-quadruplex structures in the HIV-1 Nef coding region: implications for antiviral activity R Perrone, M Nadai, JA Poe, I Frasson, M Palumbo, G Palu, TE Smithgall, ... PloS one 8 (8), e73121, 2013 | 125 | 2013 |
Inhibition of gene expression in human cells through small molecule-RNA interactions S Hwang, N Tamilarasu, K Ryan, I Huq, S Richter, WC Still, TM Rana Proceedings of the National Academy of Sciences 96 (23), 12997-13002, 1999 | 123 | 1999 |
Specific HIV-1 TAR RNA loop sequence and functional groups are required for human cyclin T1− Tat− TAR ternary complex formation S Richter, H Cao, TM Rana Biochemistry 41 (20), 6391-6397, 2002 | 122 | 2002 |
Photogeneration and reactivity of naphthoquinone methides as purine selective DNA alkylating agents D Verga, M Nadai, F Doria, C Percivalle, M Di Antonio, M Palumbo, ... Journal of the American Chemical Society 132 (41), 14625-14637, 2010 | 114 | 2010 |
Synthesis, binding and antiviral properties of potent core-extended naphthalene diimides targeting the HIV-1 long terminal repeat promoter G-quadruplexes R Perrone, F Doria, E Butovskaya, I Frasson, S Botti, M Scalabrin, S Lago, ... Journal of medicinal chemistry 58 (24), 9639-9652, 2015 | 110 | 2015 |
The frameshift signal of HIV-1 involves a potential intramolecular triplex RNA structure JD Dinman, S Richter, EP Plant, RC Taylor, AB Hammell, TM Rana Proceedings of the National Academy of Sciences 99 (8), 5331-5336, 2002 | 105 | 2002 |
KPC-mediated resistance in Klebsiella pneumoniae in two hospitals in Padua, Italy, June 2009-December 2011: massive spreading of a KPC-3-encoding plasmid … SN Richter, I Frasson, E Franchin, C Bergo, E Lavezzo, L Barzon, ... Gut pathogens 4, 1-9, 2012 | 103 | 2012 |
Hybrid ligand–alkylating agents targeting telomeric G-quadruplex structures F Doria, M Nadai, M Folini, M Di Antonio, L Germani, C Percivalle, C Sissi, ... Organic & biomolecular chemistry 10 (14), 2798-2806, 2012 | 103 | 2012 |
Viral G-quadruplexes: New frontiers in virus pathogenesis and antiviral therapy E Ruggiero, SN Richter Annual reports in medicinal chemistry 54, 101-131, 2020 | 98 | 2020 |
Antiviral properties of quinolone-based drugs S Richter, C Parolin, M Palumbo, G Palù Current Drug Targets-Infectious Disorders 4 (2), 111-116, 2004 | 96 | 2004 |