Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence MG Vizioli, T Liu, KN Miller, NA Robertson, K Gilroy, AB Lagnado, ... Genes & development 34 (5-6), 428-445, 2020 | 243 | 2020 |
TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence TG Bird, M Müller, L Boulter, DF Vincent, RA Ridgway, ... Science translational medicine 10 (454), eaan1230, 2018 | 214 | 2018 |
Notch signaling mediates secondary senescence YV Teo, N Rattanavirotkul, N Olova, A Salzano, A Quintanilla, N Tarrats, ... Cell reports 27 (4), 997-1007. e5, 2019 | 105 | 2019 |
Specificity and off-target effects of AAV8-TBG viral vectors for the manipulation of hepatocellular gene expression in mice C Kiourtis, A Wilczynska, C Nixon, W Clark, S May, TG Bird Biology Open 10 (9), bio058678, 2021 | 32 | 2021 |
Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver VJA Barthet, M Brucoli, MJGW Ladds, C Nössing, C Kiourtis, AD Baudot, ... Science Advances 7 (23), eabf9141, 2021 | 29 | 2021 |
p53-mediated redox control promotes liver regeneration and maintains liver function in response to CCl4 TJ Humpton, H Hall, C Kiourtis, C Nixon, W Clark, A Hedley, R Shaw, ... Cell Death & Differentiation 29 (3), 514-526, 2022 | 21 | 2022 |
Anti–Cholestatic Therapy with obeticholic acid improves short-term memory in bile duct–ligated mice LMV Gee, B Barron-Millar, J Leslie, C Richardson, MYW Zaki, S Luli, ... The American Journal of Pathology 193 (1), 11-26, 2023 | 9 | 2023 |
Absent expansion of AXIN2+ hepatocytes and altered physiology in Axin2CreERT2 mice challenges the role of pericentral hepatocytes in homeostatic liver regeneration S May, M Müller, CR Livingstone, GL Skalka, PJ Walsh, C Nixon, ... Journal of Hepatology 78 (5), 1028-1036, 2023 | 6* | 2023 |
A noninvasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo TJ Humpton, AK Hock, C Kiourtis, M De Donatis, F Fercoq, C Nixon, ... Science signaling 15 (720), eabd9099, 2022 | 6 | 2022 |
Human-correlated genetic HCC models identify combination therapy for precision medicine M Müller, S May, H Hall, TJ Kendall, L McGarry, L Blukacz, S Nuciforo, ... | 4 | 2022 |
Establishment of Tumour Progression Scale for Invasive Bladder Cancer Models CJS Kung, C Kiourtis, S Fraser, OJ Sansom, T Iwata JOURNAL OF PATHOLOGY 238, S13-S13, 2016 | 2 | 2016 |
Liver diseases fibrosis and cirrhosis TG Bird, C Kiourtis Cellular Senescence in Disease, 107-153, 2022 | 1 | 2022 |
Inter-organ transmission of hepatocellular senescence induces multi-organ dysfunction through the TGFβ signalling pathway. C Kiourtis, M Terradas-Terradas, LM Gee, YC Hsieh, C Nixon, W Clark, ... | 1 | 2021 |
HUMAN-CORRELATED GENETIC HCC MODELS IDENTIFY COMBINATION THERAPY FOR PRECISION MEDICINE M Mueller, S May, H Hall, TJ Kendall, L McGarry, L Blukacz, S Nuciforo, ... HEPATOLOGY 78, S101-S101, 2023 | | 2023 |
A study on the systemic transmission of cellular senescence and its role in acute liver failure C Kiourtis University of Glasgow, 2021 | | 2021 |