A patient-derived glioblastoma organoid model and biobank recapitulates inter-and intra-tumoral heterogeneity F Jacob, RD Salinas, DY Zhang, PTT Nguyen, JG Schnoll, SZH Wong, ... Cell 180 (1), 188-204. e22, 2020 | 821 | 2020 |
Sliced human cortical organoids for modeling distinct cortical layer formation X Qian, Y Su, CD Adam, AU Deutschmann, SR Pather, EM Goldberg, ... Cell stem cell 26 (5), 766-781. e9, 2020 | 372 | 2020 |
Generation of hypothalamic arcuate organoids from human induced pluripotent stem cells WK Huang, SZH Wong, SR Pather, PTT Nguyen, F Zhang, DY Zhang, ... Cell Stem Cell 28 (9), 1657-1670. e10, 2021 | 112 | 2021 |
USP7-specific inhibitors target and modify the enzyme's active site via distinct chemical mechanisms A Pozhidaeva, G Valles, F Wang, J Wu, DE Sterner, P Nguyen, ... Cell chemical biology 24 (12), 1501-1512. e5, 2017 | 94 | 2017 |
Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60 F Wang, L Wang, J Wu, I Sokirniy, P Nguyen, T Bregnard, J Weinstock, ... PloS one 12 (12), e0189744, 2017 | 51 | 2017 |
Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis LT Izzo, S Trefely, C Demetriadou, JM Drummond, T Mizukami, ... Science Advances 9 (18), eadf0115, 2023 | 47 | 2023 |
Intrinsic antiviral immunity of barrier cells revealed by an iPSC-derived blood-brain barrier cellular model Y Cheng, A Medina, Z Yao, M Basu, JP Natekar, J Lang, E Sanchez, ... Cell reports 39 (9), 2022 | 16 | 2022 |
Epigenetic crosstalk: Pharmacological inhibition of HDACs can rescue defective synaptic morphology and neurotransmission phenotypes associated with loss of the chromatin reader … NK Latcheva, JM Viveiros, EA Waddell, PTT Nguyen, FLW Liebl, ... Molecular and Cellular Neuroscience 87, 77-85, 2018 | 16 | 2018 |
Acly Deficiency Enhances Myelopoiesis through Acetyl Coenzyme A and Metabolic–Epigenetic Cross-Talk DL Greenwood, HE Ramsey, PTT Nguyen, AR Patterson, K Voss, ... ImmunoHorizons 6 (12), 837-850, 2022 | 4 | 2022 |
Bempedoic acid suppresses diet-induced hepatic steatosis independently of ATP-citrate lyase JY Liu, RS Kuna, LV Pinheiro, PTT Nguyen, JE Welles, JM Drummond, ... Cell Metabolism, 2024 | 2 | 2024 |
ACLY alternative splicing correlates with cancer phenotypes JG Supplee, HC Affronti, R Duan, RC Brooks, ZE Stine, PTT Nguyen, ... Journal of Biological Chemistry, 107418, 2024 | 1 | 2024 |
Pluripotent stem cell–derived brain-region-specific organoids PTT Nguyen, H Song, G Ming iPSCs in Tissue Engineering, 1-43, 2021 | | 2021 |