Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing L Zhang, NT Tran, H Su, R Wang, Y Lu, H Tang, S Aoyagi, A Guo, ... Elife 4, e07938, 2015 | 150 | 2015 |
Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line VT Chu, R Graf, T Wirtz, T Weber, J Favret, X Li, K Petsch, NT Tran, ... Proceedings of the National Academy of Sciences 113 (44), 12514-12519, 2016 | 143 | 2016 |
The AS‐RBM15 lncRNA enhances RBM15 protein translation during megakaryocyte differentiation NT Tran, H Su, A Khodadadi‐Jamayran, S Lin, L Zhang, D Zhou, ... EMBO reports 17 (6), 887-900, 2016 | 76 | 2016 |
Enhancement of precise gene editing by the association of Cas9 with homologous recombination factors NT Tran, S Bashir, X Li, J Rossius, VT Chu, K Rajewsky, R Kühn Frontiers in genetics 10, 365, 2019 | 73 | 2019 |
Efficient and precise CRISPR/Cas9-mediated MECP2 modifications in human-induced pluripotent stem cells TTH Le, NT Tran, TML Dao, DD Nguyen, HD Do, TL Ha, R Kühn, ... Frontiers in genetics 10, 625, 2019 | 40 | 2019 |
Efficient differentiation of human pluripotent stem cells into mesenchymal stem cells by modulating intracellular signaling pathways in a feeder/serum-free system NT Tran, QM Trinh, GM Lee, YM Han Stem Cells and Development 21 (7), 1165-1175, 2012 | 37 | 2012 |
CRISPR-Cas9-mediated ELANE mutation correction in hematopoietic stem and progenitor cells to treat severe congenital neutropenia NT Tran, R Graf, A Wulf-Goldenberg, M Stecklum, G Strauß, R Kühn, ... Molecular Therapy 28 (12), 2621-2634, 2020 | 34 | 2020 |
Efficient CRISPR/Cas9-mediated gene knockin in mouse hematopoietic stem and progenitor cells NT Tran, T Sommermann, R Graf, J Trombke, J Pempe, K Petsch, R Kühn, ... Cell reports 28 (13), 3510-3522. e5, 2019 | 33 | 2019 |
Splicing factor SF3B1K700E mutant dysregulates erythroid differentiation via aberrant alternative splicing of transcription factor TAL1 S Jin, H Su, NT Tran, J Song, SS Lu, Y Li, S Huang, O Abdel-Wahab, ... PloS one 12 (5), e0175523, 2017 | 33 | 2017 |
Precise CRISPR-Cas–mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells NT Tran, E Danner, X Li, R Graf, M Lebedin, K de la Rosa, R Kühn, ... Science Advances 8 (22), eabm9106, 2022 | 22 | 2022 |
Methylation of dual-specificity phosphatase 4 controls cell differentiation H Su, M Jiang, C Senevirathne, S Aluri, T Zhang, H Guo, J Xavier-Ferrucio, ... Cell reports 36 (4), 2021 | 15 | 2021 |
Protocol for efficient CRISPR/Cas9/AAV-mediated homologous recombination in mouse hematopoietic stem and progenitor cells NT Tran, J Trombke, K Rajewsky STAR protocols 1 (1), 100028, 2020 | 8 | 2020 |
Variable allelic expression of imprinted genes in human pluripotent stem cells during differentiation into specialized cell types in vitro SW Park, J Kim, JL Park, JY Ko, I Im, HS Do, H Kim, NT Tran, SH Lee, ... Biochemical and Biophysical Research Communications 446 (2), 493-498, 2014 | 8 | 2014 |
PRMT1-Mediated methylation of DUSP4 determines megakaryocyte-erythroid lineage choice by regulating p38 signaling H Su, NT Tran, H Guo, M Luo, X Zhao Blood, The Journal of the American Society of Hematology 126 (23), 2387-2387, 2015 | 4 | 2015 |
Protein arginine methyltransferase 1 is a therapeutic vulnerability in multiple myeloma HP Nguyen, AQ Le, E Liu, A Cesarano, F DiMeo, F Perna, R Kapur, ... Frontiers in Immunology 14, 1239614, 2023 | 2 | 2023 |
High PRMT1 expression promotes the progression of acute megakaryocytic leukemia via controlling metabolic pathways H Su, H Guo, NT Tran, M Luo, X Zhao Blood 128 (22), 1551, 2016 | 2 | 2016 |
The TAL1 short isoform generated by PRMT1-mediated alternative RNA splicing promotes erythroid differentiation S Jin, NT Tran, H Su, S Huang, X Zhao, Y Liu Blood 128 (22), 1249, 2016 | 2 | 2016 |
RBM15-Mediated RNA Splicing Fine-Tunes Epigenetic Program through Interaction with SF3B1 T Ngoc-Tung, H Su, Y Lu, CS Leslie, X Zhao Blood 126 (23), 4110, 2015 | 1 | 2015 |
Transcription activation of an antisense long noncoding RNA (lnc-Mega1) of RBM15 by RUNX1 enhances megakaryocyte differentiation X Zhao, NT Tran, D Zhou, H Su, L Zhang, TM Townes Blood, The Journal of the American Society of Hematology 124 (21), 4305-4305, 2014 | 1 | 2014 |
The Oligosaccharyltransferase Complex: A Novel Vulnerability in Multiple Myeloma HP Nguyen, AQ Le, E Liu, BA Walker, NT Tran Blood 142, 4664, 2023 | | 2023 |