PPARγ and PPARα synergize to induce robust browning of white fat in vivo T Kroon, M Harms, S Maurer, L Bonnet, I Alexandersson, A Lindblom, ... Molecular metabolism 36, 100964, 2020 | 63 | 2020 |
The SGLT2 inhibitor dapagliflozin promotes systemic FFA mobilization, enhances hepatic β-oxidation, and induces ketosis K Wallenius, T Kroon, T Hagstedt, L Löfgren, M Sörhede-Winzell, ... Journal of lipid research 63 (3), 2022 | 41 | 2022 |
BMP4 gene therapy enhances insulin sensitivity but not adipose tissue browning in obese mice JM Hoffmann, JR Grünberg, A Hammarstedt, T Kroon, TU Greiner, ... Molecular metabolism 32, 15-26, 2020 | 23 | 2020 |
In vivo liposomal delivery of PPARα/γ dual agonist tesaglitazar in a model of obesity enriches macrophage targeting and limits liver and kidney drug effects V Osinski, DK Bauknight, SSK Dasa, MJ Harms, T Kroon, MA Marshall, ... Theranostics 10 (2), 585, 2020 | 22 | 2020 |
Nicotinic acid timed to feeding reverses tissue lipid accumulation and improves glucose control in obese Zucker rats [S] T Kroon, T Baccega, A Olsén, J Gabrielsson, ND Oakes Journal of lipid research 58 (1), 31-41, 2017 | 22 | 2017 |
Feedback modeling of non-esterified fatty acids in obese Zucker rats after nicotinic acid infusions C Ahlström, T Kroon, LA Peletier, J Gabrielsson Journal of pharmacokinetics and pharmacodynamics 40, 623-638, 2013 | 17 | 2013 |
Dosing profile profoundly influences nicotinic acid's ability to improve metabolic control in rats T Kroon, A Kjellstedt, P Thalén, J Gabrielsson, ND Oakes Journal of Lipid Research 56 (9), 1679-1690, 2015 | 16 | 2015 |
Cellular senescence in hepatocytes contributes to metabolic disturbances in NASH L Bonnet, I Alexandersson, RK Baboota, T Kroon, J Oscarsson, U Smith, ... Frontiers in Endocrinology 13, 957616, 2022 | 15 | 2022 |
Modeling of free fatty acid dynamics: insulin and nicotinic acid resistance under acute and chronic treatments R Andersson, T Kroon, J Almquist, M Jirstrand, ND Oakes, ND Evans, ... Journal of Pharmacokinetics and Pharmacodynamics 44 (3), 203-222, 2017 | 14 | 2017 |
Chronotherapy with a glucokinase activator profoundly improves metabolism in obese Zucker rats T Kroon, T Hagstedt, I Alexandersson, A Ferm, M Petersson, S Maurer, ... Science Translational Medicine 14 (668), eabh1316, 2022 | 7 | 2022 |
Mitochondrial amidoxime‐reducing component 1 p. Ala165Thr increases protein degradation mediated by the proteasome T Dutta, K Sasidharan, E Ciociola, G Pennisi, FR Noto, L Kovooru, ... Liver International 44 (5), 1219-1232, 2024 | 6 | 2024 |
Optimizing nicotinic acid delivery for durable antilipolysis and improved metabolic control P Kroon, T Kroon Acta Universitatis Agriculturae Sueciae, 2016 | 2 | 2016 |
1881-P: The SGLT2 Inhibitor Dapagliflozin Improves Glucose Control and Enhances Liver Fatty Acid Oxidation and Ketone Body Formation in Insulin Resistant Obese Zucker Rats T KROON, T HAGSTEDT, ANN KJELLSTEDT, A LINDBLOM, L LÖFGREN, ... Diabetes 68 (Supplement_1), 2019 | 1 | 2019 |
193-OR: Chronotherapy with the Glucokinase Activator AZD1656 Greatly Affects Its Ability to Improve Metabolism in Obese Zucker Rats T Kroon, T Hagstedt, I Alexandersson, A Ferm, M Petersson, S Maurer, ... Diabetes 71 (Supplement_1), 2022 | | 2022 |
BMP4 gene therapy delays diabetes progression in the diabetic db/db mouse model RK Shahidi, LM Holm, L Bonnet, T Kroon, D Nilsson, A Ahnmark, I Elias, ... DIABETOLOGIA 62, S122-S122, 2019 | | 2019 |
1953-P: PPARγ Agonism and FGF-21 Synergize to Robustly Induce Browning of White Fat T Kroon, MJ Harms, D Nilsson, A Lindblom, P Gennemark, G O'MAHONY, ... Diabetes 68 (Supplement_1), 2019 | | 2019 |
The dual PPAR alpha/gamma-agonist tesaglitazar robustly induces browning of white fat in vitro and in vivo T Kroon, M Harms, D Nilsson, A Lindblom, P Gennemark, G O'Mahony, ... DIABETOLOGIA 61, S102-S102, 2018 | | 2018 |
The abruptness of terminating nicotinic acid delivery has a profound effect on free fatty acid and insulin rebound in rats T Kroon, J Gabrielsson, ND Oakes DIABETOLOGIA 58, S568-S568, 2015 | | 2015 |
Intermittent, but Not Continuous, Nicotinic Acid (NiAc) Infusion Preserves Plasma Free Fatty Acid (FFA) Lowering and Ameliorates Insulin Resistance in Obese Zucker Rats T Kroon, P Thalen, A Kjellstedt, J Gabrielsson, ND Oakes DIABETES 63, A470-A470, 2014 | | 2014 |