New approaches to the treatment of inflammatory disorders small molecule inhibitors of p38 MAP kinase C Peifer, G Wagner, S Laufer Current topics in medicinal chemistry 6 (2), 113-149, 2006 | 180 | 2006 |
A survey of chemical methods for sugar-nucleotide synthesis GK Wagner, T Pesnot, RA Field Natural product reports 26 (9), 1172-1194, 2009 | 178 | 2009 |
Studies on the anti-inflammatory activity of phytopharmaceuticals prepared from Arnica flowers CA Klaas, G Wagner, S Laufer, S Sosa, R Della Loggia, U Bomme, ... Planta medica 68 (05), 385-391, 2002 | 170 | 2002 |
Small molecular anti‐cytokine agents G Wagner, S Laufer Medicinal research reviews 26 (1), 1-62, 2006 | 142 | 2006 |
Novel substituted pyridinyl imidazoles as potent anticytokine agents with low activity against hepatic cytochrome P450 enzymes SA Laufer, GK Wagner, DA Kotschenreuther, W Albrecht Journal of medicinal chemistry 46 (15), 3230-3244, 2003 | 130 | 2003 |
Glycosyltransferases and their assays GK Wagner, T Pesnot ChemBioChem 11 (14), 1939-1949, 2010 | 115 | 2010 |
Trypanosoma brucei: chemical evidence that cathepsin L is essential for survival and a relevant drug target D Steverding, DW Sexton, X Wang, SS Gehrke, GK Wagner, CR Caffrey International journal for parasitology 42 (5), 481-488, 2012 | 97 | 2012 |
Structural and mechanistic basis for a new mode of glycosyltransferase inhibition T Pesnot, R Jørgensen, MM Palcic, GK Wagner Nature chemical biology 6 (5), 321-323, 2010 | 95 | 2010 |
Ones, Thiones, and N‐Oxides: An Exercise in Imidazole Chemistry S Laufer, G Wagner, D Kotschenreuther Angewandte Chemie International Edition 41 (13), 2290-2293, 2002 | 95 | 2002 |
Imidazole inhibitors of cytokine release: probing substituents in the 2 position SA Laufer, HG Striegel, GK Wagner Journal of medicinal chemistry 45 (21), 4695-4705, 2002 | 88 | 2002 |
First small molecular inhibitors of T. brucei dolicholphosphate mannose synthase (DPMS), a validated drug target in African sleeping sickness TK Smith, BL Young, H Denton, DL Hughes, GK Wagner Bioorganic & medicinal chemistry letters 19 (6), 1749-1752, 2009 | 76 | 2009 |
From imidazoles to pyrimidines: new inhibitors of cytokine release SA Laufer, GK Wagner Journal of medicinal chemistry 45 (13), 2733-2740, 2002 | 69 | 2002 |
A facile two-step synthesis of 8-arylated guanosine mono-and triphosphates (8-aryl GXPs) A Collier, G Wagner Organic & Biomolecular Chemistry 4 (24), 4526-4532, 2006 | 66 | 2006 |
Novel derivatives of UDP-glucose: concise synthesis and fluorescent properties T Pesnot, GK Wagner Organic & Biomolecular Chemistry 6 (16), 2884-2891, 2008 | 62 | 2008 |
Rapid synthetic route toward structurally modified derivatives of cyclic adenosine 5 ‘-diphosphate ribose GK Wagner, AH Guse, BVL Potter The Journal of Organic Chemistry 70 (12), 4810-4819, 2005 | 60 | 2005 |
Inhibition of galactosyltransferases by a novel class of donor analogues K Descroix, T Pesnot, Y Yoshimura, SS Gehrke, W Wakarchuk, MM Palcic, ... Journal of Medicinal Chemistry 55 (5), 2015-2024, 2012 | 50 | 2012 |
Structural Determinants for N1/N7 Cyclization of Nicotinamide Hypoxanthine 5 ‘-Dinucleotide (NHD+) Derivatives by ADP-Ribosyl Cyclase from Aplysia californica: Ca2+-Mobilizing … C Moreau, GK Wagner, K Weber, AH Guse, BVL Potter Journal of medicinal chemistry 49 (17), 5162-5176, 2006 | 47 | 2006 |
Identification of Regioisomers in a Series of N-Substituted Pyridin-4-yl Imidazole Derivatives by Regiospecific Synthesis, GC/MS, and 1H NMR GK Wagner, D Kotschenreuther, W Zimmermann, SA Laufer The Journal of organic chemistry 68 (11), 4527-4530, 2003 | 47 | 2003 |
Rationally designed squaryldiamides–a novel class of sugar-nucleotide mimics? S Niewiadomski, Z Beebeejaun, H Denton, TK Smith, RJ Morris, ... Organic & biomolecular chemistry 8 (15), 3488-3499, 2010 | 44 | 2010 |
2′-Deoxy cyclic adenosine 5′-diphosphate ribose derivatives: importance of the 2′-hydroxyl motif for the antagonistic activity of 8-substituted cADPR derivatives B Zhang, GK Wagner, K Weber, C Garnham, AJ Morgan, A Galione, ... Journal of medicinal chemistry 51 (6), 1623-1636, 2008 | 44 | 2008 |