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Christian Hobson
Christian Hobson
Senior Scientist & Head of Chemical Development, Willow Biosciences
在 willowbio.com 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
The antibiotic resistome: a guide for the discovery of natural products as antimicrobial agents
C Hobson, AN Chan, GD Wright
Chemical Reviews 121 (6), 3464-3494, 2021
1482021
An unusual Burkholderia gladioli double chain-initiating nonribosomal peptide synthetase assembles ‘fungal’icosalide antibiotics
M Jenner, X Jian, Y Dashti, J Masschelein, C Hobson, DM Roberts, ...
Chemical science 10 (21), 5489-5494, 2019
412019
A dual transacylation mechanism for polyketide synthase chain release in enacyloxin antibiotic biosynthesis
J Masschelein, PK Sydor, C Hobson, R Howe, C Jones, DM Roberts, ...
Nature chemistry 11 (10), 906-912, 2019
342019
ClpP inhibitors are produced by a widespread family of bacterial gene clusters
EJ Culp, D Sychantha, C Hobson, AC Pawlowski, G Prehna, GD Wright
Nature Microbiology 7 (3), 451-462, 2022
232022
NMR-based assignment of isoleucine vs. allo-isoleucine stereochemistry
ZJ Anderson, C Hobson, R Needley, L Song, MS Perryman, P Kerby, ...
Organic & Biomolecular Chemistry 15 (44), 9372-9378, 2017
122017
Synthesis of enantiomerically-enriched N-aryl amino-amides via a Jocic-type reaction
C Hobson, MS Perryman, G Kirby, GJ Clarkson, DJ Fox
Tetrahedron Letters 59 (44), 3965-3968, 2018
62018
Three-dimensional structure and optimization of the metallo-β-lactamase inhibitor aspergillomarasmine A
K Koteva, D Sychantha, CM Rotondo, C Hobson, JF Britten, GD Wright
ACS omega 7 (5), 4170-4184, 2022
52022
Diene incorporation by a dehydratase domain variant in modular polyketide synthases
C Hobson, M Jenner, X Jian, D Griffiths, DM Roberts, M Rey-Carrizo, ...
Nature chemical biology 18 (12), 1410-1416, 2022
32022
Lessons from assembling a microbial natural product and pre-fractionated extract library in an academic laboratory
MA Cook, D Pallant, L Ejim, AD Sutherland, X Wang, JW Johnson, ...
Journal of Industrial Microbiology and Biotechnology 50 (1), kuad042, 2023
22023
Antibiotic Skeletal Diversification via Differential Enoylreductase Recruitment and Module Iteration in trans-Acyltransferase Polyketide Synthases
X Jian, F Pang, C Hobson, M Jenner, LM Alkhalaf, GL Challis
Journal of the American Chemical Society 146 (9), 6114-6124, 2024
2024
Angucyclinones rescue PhLOPSA antibiotic activity by inhibiting Cfr-dependent antibiotic resistance
AJ Schaenzer, A Rodriguez Hernandez, K Tsai, C Hobson, DG Fujimori, ...
Mbio 14 (6), e01791-23, 2023
2023
A widespread family of bacterial gene clusters produces ClpP inhibitors
G Wright, E Culp, D Sychantha, C Hobson, A Pawlowski, G Prehna
2021
A biosynthetic engineering approach to structural diversification of the enacyloxins
JR Sargeant
University of Warwick, 2021
2021
Antimicrobial agents
GL Challis, J Xinyun, C Hobson, JSL Masschelein
US Patent App. 16/606,845, 2020
2020
Phytochemical Investigation of Iphiona aucheri. Structural Revision of Donine
Y Dashti, C Hobson, FM Tajabadi, H Rezadoost
Chemistry of Natural Compounds 55, 902-907, 2019
2019
Biosynthesis and bioengineering of antibiotics in Burkholderia species
C Hobson
University of Warwick, 2019
2019
Antimicrobial Agents. PCT Int. Appl., 2018, WO/2018/193273
J Masschelein, X Jian, C Hobson, GL Challis
2018
Data for Synthesis of enantiomerically-enriched N-aryl amino-amides via Jocic-type reaction
C Hobson, MS Perryman, G Kirby, GJ Clarkson, DJ Fox
University of Warwick, Department of Chemistry, 2018
2018
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