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| Fisetin is a senotherapeutic that extends health and lifespan MJ Yousefzadeh, Y Zhu, SJ McGowan, L Angelini, ... EBioMedicine 36, 18-28, 2018 | 705 | 2018 |
| Expression of p16INK4a in peripheral blood T‐cells is a biomarker of human aging Y Liu, HK Sanoff, H Cho, CE Burd, C Torrice, JG Ibrahim, NE Thomas, ... Aging cell 8 (4), 439-448, 2009 | 511 | 2009 |
| An aged immune system drives senescence and ageing of solid organs MJ Yousefzadeh, RR Flores, Y Zhu, ZC Schmiechen, RW Brooks, ... Nature 594 (7861), 100-105, 2021 | 487 | 2021 |
| Monitoring tumorigenesis and senescence in vivo with a p16INK4a-luciferase model CE Burd, JA Sorrentino, KS Clark, DB Darr, J Krishnamurthy, AM Deal, ... Cell 152 (1), 340-351, 2013 | 438 | 2013 |
| The Molecular Balancing Act of p16INK4a in Cancer and Aging KM LaPak, CE Burd Molecular Cancer Research 12 (2), 167-183, 2014 | 352 | 2014 |
| INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis Y Liu, HK Sanoff, H Cho, CE Burd, C Torrice, KL Mohlke, JG Ibrahim, ... PloS one 4 (4), e5027, 2009 | 297 | 2009 |
| The xenoestrogen bisphenol A induces inappropriate androgen receptor activation and mitogenesis in prostatic adenocarcinoma cells YB Wetherill, CE Petre, KR Monk, A Puga, KE Knudsen Molecular cancer therapeutics 1 (7), 515-524, 2002 | 269 | 2002 |
| Mutation-specific RAS oncogenicity explains NRAS codon 61 selection in melanoma CE Burd, W Liu, MV Huynh, MA Waqas, JE Gillahan, KS Clark, K Fu, ... Cancer discovery 4 (12), 1418-1429, 2014 | 221 | 2014 |
| Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice MJ Yousefzadeh, J Zhao, C Bukata, EA Wade, SJ McGowan, LA Angelini, ... Aging cell 19 (3), e13094, 2020 | 218 | 2020 |
| An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation GP Souroullas, WR Jeck, JS Parker, JM Simon, JY Liu, J Paulk, J Xiong, ... Nature medicine 22 (6), 632-640, 2016 | 215 | 2016 |
| Liposomal daunorubicin as treatment for Kaposi’s sarcoma CE Petre, DP Dittmer International journal of nanomedicine 2 (3), 277-288, 2007 | 198 | 2007 |
| Cyclin D1: mechanism and consequence of androgen receptor co-repressor activity CE Petre, YB Wetherill, M Danielsen, KE Knudsen Journal of Biological Chemistry 277 (3), 2207-2215, 2002 | 171 | 2002 |
| Cyclin D1b variant influences prostate cancer growth through aberrant androgen receptor regulation CJ Burd, CE Petre, LM Morey, Y Wang, MP Revelo, CA Haiman, S Lu, ... Proceedings of the National Academy of Sciences 103 (7), 2190-2195, 2006 | 152 | 2006 |
| Functional p53 signaling in Kaposi's sarcoma-associated herpesvirus lymphomas: implications for therapy CE Petre, SH Sin, DP Dittmer Journal of virology 81 (4), 1912-1922, 2007 | 137 | 2007 |
| Differential requirement of SWI/SNF for androgen receptor activity TW Marshall, KA Link, CE Petre-Draviam, KE Knudsen Journal of Biological Chemistry 278 (33), 30605-30613, 2003 | 133 | 2003 |
| Melanoma models for the next generation of therapies. EE Patton, KL Mueller, DJ Adams, N Anandasabapathy, AE Aplin, ... Cancer Cell, 2021 | 120 | 2021 |
| Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging AR Robinson, MJ Yousefzadeh, TA Rozgaja, J Wang, X Li, JS Tilstra, ... Redox biology 17, 259-273, 2018 | 116 | 2018 |
| p16INK4a reporter mice reveal age-promoting effects of environmental toxicants JA Sorrentino, J Krishnamurthy, S Tilley, JG Alb, CE Burd, NE Sharpless The Journal of clinical investigation 124 (1), 169-173, 2014 | 102 | 2014 |
Norman E. SharplessFormer Director, The National Cancer Institute在 med.unc.edu 的电子邮件经过验证
