| Mechanisms of inhibition of HIV replication by non-nucleoside reverse transcriptase inhibitors N Sluis-Cremer, G Tachedjian Virus research 134 (1-2), 147-156, 2008 | 248 | 2008 |
| Conformational changes in HIV-1 reverse transcriptase induced by nonnucleoside reverse transcriptase inhibitor binding N Sluis-Cremer, NA Temiz, I Bahar Current HIV research 2 (4), 323-332, 2004 | 243 | 2004 |
| N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance SH Yap, CW Sheen, J Fahey, M Zanin, D Tyssen, VD Lima, B Wynhoven, ... PLoS Medicine 4 (12), e335, 2007 | 208 | 2007 |
| Conformational stability of pGEX‐expressed Schistosoma japonicum glutathione S‐transferase: A detoxification enzyme and fusion‐protein affinity tag W Kaplan, J Erhardt, N Sluis‐Cremer, H Dirr, P Hüsler, H Klump Protein Science 6 (2), 399-406, 1997 | 199 | 1997 |
| Inhibitors of histone deacetylases: correlation between isoform specificity and reactivation of HIV type 1 (HIV-1) from latently infected cells K Huber, G Doyon, J Plaks, E Fyne, JW Mellors, N Sluis-Cremer Journal of Biological Chemistry 286 (25), 22211-22218, 2011 | 174 | 2011 |
| Widespread Fosfomycin Resistance in Gram-Negative Bacteria Attributable to the Chromosomal fosA Gene R Ito, MM Mustapha, AD Tomich, JD Callaghan, CL McElheny, RT Mettus, ... MBio 8 (4), 10.1128/mbio. 00749-17, 2017 | 156 | 2017 |
| Molecular mechanisms of HIV-1 resistance to nucleoside reverse transcriptase inhibitors (NRTIs) N Sluis-Cremer, D Arion, MA Parniak* Cellular and Molecular Life Sciences CMLS 57, 1408-1422, 2000 | 155 | 2000 |
| Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-Pol A Figueiredo, KL Moore, J Mak, N Sluis-Cremer, MP de Bethune, ... PLoS pathogens 2 (11), e119, 2006 | 128 | 2006 |
| Disulfiram reactivates latent HIV-1 expression through depletion of the phosphatase and tensin homolog G Doyon, J Zerbato, JW Mellors, N Sluis-Cremer Aids 27 (2), F7-F11, 2013 | 125 | 2013 |
| Selection of mutations in the connection and RNase H domains of human immunodeficiency virus type 1 reverse transcriptase that increase resistance to 3′-azido-3′-dideoxythymidine JH Brehm, D Koontz, JD Meteer, V Pathak, N Sluis-Cremer, JW Mellors Journal of virology 81 (15), 7852-7859, 2007 | 117 | 2007 |
| Molecular mechanisms of bidirectional antagonism between K65R and thymidine analog mutations in HIV-1 reverse transcriptase UM Parikh, S Zelina, N Sluis-Cremer, JW Mellors Aids 21 (11), 1405-1414, 2007 | 112 | 2007 |
| Destabilization of the HIV-1 reverse transcriptase dimer upon interaction with N-acyl hydrazone inhibitors N Sluis-Cremer, D Arion, MA Parniak Molecular Pharmacology 62 (2), 398-405, 2002 | 107 | 2002 |
| Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay H Xu, T Franks, G Gibson, K Huber, N Rahm, CS De Castillia, J Luban, ... Retrovirology 10, 1-16, 2013 | 100 | 2013 |
| Naive CD4+ T cells harbor a large inducible reservoir of latent, replication-competent human immunodeficiency virus type 1 JM Zerbato, DK McMahon, MD Sobolewski, JW Mellors, N Sluis-Cremer Clinical Infectious Diseases 69 (11), 1919-1925, 2019 | 94 | 2019 |
| Novel assay reveals a large, inducible, replication-competent HIV-1 reservoir in resting CD4+ T cells A Sanyal, RB Mailliard, CR Rinaldo, D Ratner, M Ding, Y Chen, ... Nature medicine 23 (7), 885-889, 2017 | 93 | 2017 |
| Human Immunodeficiency Virus Type 1 Reverse Transcriptase Dimer Destabilization by 1-{Spiro [4 ‘‘-amino-2 ‘‘, 2 ‘‘-dioxo-1 ‘‘, 2 ‘‘-oxathiole-5 ‘‘, 3 ‘-[2 ‘, 5 ‘-bis-O-(tert … N Sluis-Cremer, GI Dmitrienko, J Balzarini, MJ Camarasa, MA Parniak Biochemistry 39 (6), 1427-1433, 2000 | 93 | 2000 |
| Molecular mechanism by which the K70E mutation in human immunodeficiency virus type 1 reverse transcriptase confers resistance to nucleoside reverse transcriptase inhibitors N Sluis-Cremer, CW Sheen, S Zelina, PSA Torres, UM Parikh, JW Mellors Antimicrobial agents and chemotherapy 51 (1), 48-53, 2007 | 92 | 2007 |
| Mechanism by which phosphonoformic acid resistance mutations restore 3′-azido-3′-deoxythymidine (AZT) sensitivity to AZT-resistant HIV-1 reverse transcriptase D Arion, N Sluis-Cremer, MA Parniak Journal of Biological Chemistry 275 (13), 9251-9255, 2000 | 90 | 2000 |
| Probing nonnucleoside inhibitor‐induced active‐site distortion in HIV‐1 reverse transcriptase by transient kinetic analyses Q Xia, J Radzio, KS Anderson, N Sluis‐Cremer Protein science 16 (8), 1728-1737, 2007 | 89 | 2007 |
| Equilibrium and kinetic unfolding properties of dimeric human glutathione transferase A1-1 LA Wallace, N Sluis-Cremer, HW Dirr Biochemistry 37 (15), 5320-5328, 1998 | 89 | 1998 |
