A controlled NO-releasing compound: synthesis, molecular structure, spectroscopy, electrochemistry, and chemical reactivity of R, R, S, S-trans-[RuCl (NO)(cyclam)] 2+(1, 4, 8 … DR Lang, JA Davis, LGF Lopes, AA Ferro, LCG Vasconcellos, DW Franco, ... Inorganic chemistry 39 (11), 2294-2300, 2000 | 176 | 2000 |
Novel ruthenium complexes as potential drugs for Chagas's disease: enzyme inhibition and in vitro/in vivo trypanocidal activity JJN Silva, PMM Guedes, A Zottis, TL Balliano, FO Nascimento Silva, ... British journal of pharmacology 160 (2), 260-269, 2010 | 109 | 2010 |
Cis-and trans-nitrosyltetraammineruthenium (II). Spectral and electrochemical properties and reactivity MG Gomes, CU Davanzo, SC Silva, LGF Lopes, PS Santos, DW Franco Journal of the Chemical Society, Dalton Transactions, 601-608, 1998 | 97 | 1998 |
The trans-labilization of nitric oxide in RuII complexes by C-bound imidazoles LGF Lopes, A Wieraszko, Y El-Sherif, MJ Clarke Inorganica Chimica Acta 312 (1-2), 15-22, 2001 | 81 | 2001 |
Reactivity of trans-[Ru (NH3) 4P (OEt) 3NO] X3 (X= PF6-, CF3COO-): modulation of the release of NO by the trans-effect LGF Lopes, EE Castellano, AG Ferreira, CU Davanzo, MJ Clarke, ... Inorganica Chimica Acta 358 (10), 2883-2890, 2005 | 61 | 2005 |
Aryl-substituted ruthenium (II) complexes: a strategy for enhanced photocleavage and efficient DNA binding FD Abreu, TF Paulo, MH Gehlen, RA Ando, LGF Lopes, ACS Gondim, ... Inorganic Chemistry 56 (15), 9084-9096, 2017 | 57 | 2017 |
Release of NO by a nitrosyl complex upon activation by the mitochondrial reducing power JC Toledo Jr, LG de França Lopes, AA Alves, LP da Silva, DW Franco Journal of inorganic biochemistry 89 (3-4), 267-271, 2002 | 57 | 2002 |
Thiol-activated HNO release from a ruthenium antiangiogenesis complex and HIF-1α inhibition for cancer therapy EH Silva Sousa, LA Ridnour, FS Gouveia Jr, CD Silva da Silva, DA Wink, ... ACS Chemical Biology 11 (7), 2057-2065, 2016 | 55 | 2016 |
Isoniazid metal complex reactivity and insights for a novel anti-tuberculosis drug design EHS Sousa, LA Basso, DS Santos, ICN Diógenes, E Longhinotti, ... JBIC Journal of Biological Inorganic Chemistry 17, 275-283, 2012 | 52 | 2012 |
Synthesis, Characterization, and NO Release Study of the cis‐ and trans‐[Ru(Bpy)2(SO3)(NO)]+ Complexes FON Silva, SXB Araújo, AKM Holanda, E Meyer, FAM Sales, ... European Journal of Inorganic Chemistry 2006 (10), 2020-2026, 2006 | 47 | 2006 |
The influence of NO-containing ruthenium complexes on mouse hippocampal evoked potentials in vitro A Wieraszko, MJ Clarke, DR Lang, LGF Lopes, DW Franco Life Sciences 68 (13), 1535-1544, 2001 | 47 | 2001 |
Mechanism and biological implications of the NO release of cis-[Ru (bpy) 2L (NO)] n+ complexes: A key role of physiological thiols FON Silva, MCL Cândido, AKM Holanda, ICN Diógenes, EHS Sousa, ... Journal of Inorganic Biochemistry 105 (5), 624-629, 2011 | 45 | 2011 |
Nitric oxide and Brazilian propolis combined accelerates tissue repair by modulating cell migration, cytokine production and collagen deposition in experimental leishmaniasis MM Miranda, C Panis, AHD Cataneo, SS da Silva, NY Kawakami, ... PLoS One 10 (5), e0125101, 2015 | 44 | 2015 |
Nitric oxide as a central molecule in hypertension: Focus on the vasorelaxant activity of new nitric oxide donors GM da Silva, MC da Silva, DVG Nascimento, EM Lima Silva, FFF Gouvêa, ... Biology 10 (10), 1041, 2021 | 41 | 2021 |
Preconditioning with a novel metallopharmaceutical NO donor in anesthetized rats subjected to brain ischemia/reperfusion MWS Campelo, RB Oriá, LG de França Lopes, GAC Brito, AA dos Santos, ... Neurochemical research 37, 749-758, 2012 | 39 | 2012 |
The nitric oxide donor cis-[Ru (bpy) 2 (SO3) NO](PF6) increases gastric mucosa protection in mice–Involvement of the soluble guanylate cyclase/KATP pathway APM Santana, BM Tavares, LT Lucetti, FS Gouveia Jr, RA Ribeiro, ... Nitric Oxide 45, 35-42, 2015 | 38 | 2015 |
Antitubercular activity of Ru (II) isoniazid complexes I de Aguiar, A Tavares, AC Roveda Jr, ACH da Silva, LB Marino, ... European Journal of Pharmaceutical Sciences 70, 45-54, 2015 | 35 | 2015 |
Activity of IQG-607, a new orally active compound, in a murine model of Mycobacterium tuberculosis infection VS Rodrigues-Junior, A dos Santos Junior, AJ Dos Santos, CZ Schneider, ... International journal of antimicrobial agents 40 (2), 182-185, 2012 | 35 | 2012 |
Electron transfer kinetics and mechanistic study of the thionicotinamide coordinated to the pentacyanoferrate (III)/(II) complexes: a model system for the in vitro activation … EHS Sousa, DL Pontes, ICN Diogenes, LGF Lopes, JS Oliveira, LA Basso, ... Journal of inorganic biochemistry 99 (2), 368-375, 2005 | 33 | 2005 |
Photochemical and Electrochemical Study of the Release of Nitric Oxide from [Ru(bpy)2L(NO)](PF6)n Complexes (L = Imidazole, 1-Methylimidazole, Sulfite and … MCL Cândido, AM Oliveira, FON Silva, AKM Holanda, WG Pereira, ... Journal of the Brazilian Chemical Society 26 (9), 1824-1830, 2015 | 31 | 2015 |