The dopaminergic stabilizers pridopidine (ACR16) and (−)-OSU6162 display dopamine D2 receptor antagonism and fast receptor dissociation properties T Dyhring, EØ Nielsen, C Sonesson, F Pettersson, J Karlsson, ... European journal of pharmacology 628 (1-3), 19-26, 2010 | 108 | 2010 |
Structural and functional characterization of a specific antidote for ticagrelor A Buchanan, P Newton, S Pehrsson, T Inghardt, T Antonsson, ... Blood, The Journal of the American Society of Hematology 125 (22), 3484-3490, 2015 | 98 | 2015 |
Chemical information management in drug discovery: Optimizing the computational and combinatorial chemistry interfaces TI Oprea, J Gottfries, V Sherbukhin, P Svensson, TC Kühler Journal of Molecular Graphics and Modelling 18 (4-5), 512-524, 2000 | 76 | 2000 |
Computational modelling of inhibitor binding to human thrombin KB Ljungberg, J Marelius, D Musil, P Svensson, B Norden, J Åqvist European journal of pharmaceutical sciences 12 (4), 441-446, 2001 | 67 | 2001 |
Exploration of the potential energy surface of C9H9+ by ab initio methods. 1. The barbaralyl cation D Cremer, P Svensson, E Kraka, P Ahlberg Journal of the American Chemical Society 115 (16), 7445-7456, 1993 | 65 | 1993 |
Behavioral analysis of dopaminergic activation in zebrafish and rats reveals similar phenotypes F Ek, M Malo, M Åberg Andersson, C Wedding, J Kronborg, P Svensson, ... ACS chemical neuroscience 7 (5), 633-646, 2016 | 58 | 2016 |
Exploration of the potential energy surface of C9H9+ by ab initio methods. 2. Is the 1, 4-bishomotropylium cation a bishomoaromatic prototype? D Cremer, P Svensson, E Kraka, Z Konkoli, P Ahlberg Journal of the American Chemical Society 115 (16), 7457-7464, 1993 | 47 | 1993 |
Hip to be square: oxetanes as design elements to alter metabolic pathways F Toselli, M Fredenwall, P Svensson, XQ Li, A Johansson, L Weidolf, ... Journal of Medicinal Chemistry 62 (16), 7383-7399, 2019 | 34 | 2019 |
Selective Pharmacophore Models of Dopamine D1 and D2 Full Agonists Based on Extended Pharmacophore Features M Malo, L Brive, K Luthman, P Svensson ChemMedChem: Chemistry Enabling Drug Discovery 5 (2), 232-246, 2010 | 31 | 2010 |
Heterodimer formation within universal stress protein classes revealed by an in silico and experimental approach L Nachin, L Brive, KC Persson, P Svensson, T Nyström Journal of molecular biology 380 (2), 340-350, 2008 | 29 | 2008 |
A novel series of 6-substituted 3-(pyrrolidin-1-ylmethyl) chromen-2-ones as selective monoamine oxidase (MAO) A inhibitors C Mattsson, P Svensson, C Sonesson European Journal of Medicinal Chemistry 73, 177-186, 2014 | 27 | 2014 |
State of affairs: design and structure–activity relationships of reversible P2Y12 receptor antagonists F Zetterberg, P Svensson Bioorganic & medicinal chemistry letters 26 (12), 2739-2754, 2016 | 20 | 2016 |
Investigation of D1 Receptor–Agonist Interactions and D1/D2 Agonist Selectivity Using a Combination of Pharmacophore and Receptor Homology Modeling M Malo, L Brive, K Luthman, P Svensson ChemMedChem 7 (3), 483-494, 2012 | 20 | 2012 |
Preclinical pharmacology of [2-(3-fluoro-5-methanesulfonyl-phenoxy) ethyl](propyl) amine (IRL790), a novel dopamine transmission modulator for the treatment of motor and … S Waters, C Sonesson, P Svensson, J Tedroff, M Carta, E Ljung, ... Journal of Pharmacology and Experimental Therapeutics 374 (1), 113-125, 2020 | 18 | 2020 |
Oxetane substrates of human microsomal epoxide hydrolase F Toselli, M Fredenwall, P Svensson, XQ Li, A Johansson, L Weidolf, ... Drug Metabolism and Disposition 45 (8), 966-973, 2017 | 18 | 2017 |
Synthesis and evaluation of a set of para-substituted 4-phenylpiperidines and 4-phenylpiperazines as monoamine oxidase (MAO) inhibitors F Pettersson, P Svensson, S Waters, N Waters, C Sonesson Journal of Medicinal Chemistry 55 (7), 3242-3249, 2012 | 18 | 2012 |
Investigation of D2 Receptor–Agonist Interactions Using a Combination of Pharmacophore and Receptor Homology Modeling M Malo, L Brive, K Luthman, P Svensson ChemMedChem 7 (3), 471-482, 2012 | 17 | 2012 |
Ab-initio based 13 C NMR shift calculations as a probe for carbocation structure. Homoaromaticity and rearrangements of the C 9 H 9+ ion P Svensson, F Reichel, P Ahlberg, D Cremer Journal of the Chemical Society, Perkin Transactions 2, 1463-1469, 1991 | 17 | 1991 |
Concerted synchronous two-hydron transfer within the formic acid dimer. A kinetic isotope effect study using ab initio calculations P Svensson, NÅ Bergman, P Ahlberg Journal of the Chemical Society, Chemical Communications, 862-863, 1990 | 17 | 1990 |
Oxabispidine compounds useful in the treatment of cardiac arrhyythmias A Björe, M Björsne, KJ Hoffmann, F Pontén, G Strandlund, P Svensson, ... US Patent 6,559,143, 2003 | 16 | 2003 |