Tumor cell-intrinsic factors underlie heterogeneity of immune cell infiltration and response to immunotherapy J Li, KT Byrne, F Yan, T Yamazoe, Z Chen, T Baslan, LP Richman, JH Lin, ... Immunity 49 (1), 178-193. e7, 2018 | 602 | 2018 |
Genome-wide copy number analysis of single cells T Baslan, J Kendall, L Rodgers, H Cox, M Riggs, A Stepansky, J Troge, ... Nature protocols 7 (6), 1024-1041, 2012 | 396 | 2012 |
Unravelling biology and shifting paradigms in cancer with single-cell sequencing T Baslan, J Hicks Nature Reviews Cancer 17 (9), 557-569, 2017 | 350 | 2017 |
p53 represses the mevalonate pathway to mediate tumor suppression SH Moon, CH Huang, SL Houlihan, K Regunath, WA Freed-Pastor, ... Cell 176 (3), 564-580. e19, 2019 | 333 | 2019 |
NK cell–mediated cytotoxicity contributes to tumor control by a cytostatic drug combination M Ruscetti, J Leibold, MJ Bott, M Fennell, A Kulick, NR Salgado, CC Chen, ... Science 362 (6421), 1416-1422, 2018 | 311 | 2018 |
Deletions linked to TP53 loss drive cancer through p53-independent mechanisms Y Liu, C Chen, Z Xu, C Scuoppo, CD Rillahan, J Gao, B Spitzer, ... Nature 531 (7595), 471-475, 2016 | 270 | 2016 |
Interactive analysis and assessment of single-cell copy-number variations T Garvin, R Aboukhalil, J Kendall, T Baslan, GS Atwal, J Hicks, M Wigler, ... Nature methods 12 (11), 1058-1060, 2015 | 259 | 2015 |
α-Ketoglutarate links p53 to cell fate during tumour suppression JP Morris IV, JJ Yashinskie, R Koche, R Chandwani, S Tian, CC Chen, ... Nature 573 (7775), 595-599, 2019 | 238 | 2019 |
Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer KP O'Rourke, E Loizou, G Livshits, EM Schatoff, T Baslan, E Manchado, ... Nature biotechnology 35 (6), 577-582, 2017 | 233 | 2017 |
Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line M Nattestad, S Goodwin, K Ng, T Baslan, FJ Sedlazeck, P Rescheneder, ... Genome research 28 (8), 1126-1135, 2018 | 180 | 2018 |
An approach to suppress the evolution of resistance in BRAFV600E-mutant cancer Y Xue, L Martelotto, T Baslan, A Vides, M Solomon, TT Mai, N Chaudhary, ... Nature medicine 23 (8), 929-937, 2017 | 168 | 2017 |
Rapid phenotypic and genomic change in response to therapeutic pressure in prostate cancer inferred by high content analysis of single circulating tumor cells AE Dago, A Stepansky, A Carlsson, M Luttgen, J Kendall, T Baslan, ... PloS one 9 (8), e101777, 2014 | 163 | 2014 |
The genomic landscape of male breast cancers S Piscuoglio, CKY Ng, MP Murray, E Guerini-Rocco, LG Martelotto, ... Clinical Cancer Research 22 (16), 4045-4056, 2016 | 155 | 2016 |
DNAJB1–PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma ER Kastenhuber, G Lalazar, SL Houlihan, DF Tschaharganeh, T Baslan, ... Proceedings of the National Academy of Sciences 114 (50), 13076-13084, 2017 | 150 | 2017 |
Ordered and deterministic cancer genome evolution after p53 loss T Baslan, JP Morris IV, Z Zhao, J Reyes, YJ Ho, KM Tsanov, J Bermeo, ... Nature 608 (7924), 795-802, 2022 | 140 | 2022 |
Whole-genome single-cell copy number profiling from formalin-fixed paraffin-embedded samples LG Martelotto, T Baslan, J Kendall, FC Geyer, KA Burke, L Spraggon, ... Nature medicine 23 (3), 376-385, 2017 | 137 | 2017 |
Optimizing sparse sequencing of single cells for highly multiplex copy number profiling T Baslan, J Kendall, B Ward, H Cox, A Leotta, L Rodgers, M Riggs, ... Genome research 25 (5), 714-724, 2015 | 132 | 2015 |
Cohesin members Stag1 and Stag2 display distinct roles in chromatin accessibility and topological control of HSC self-renewal and differentiation AD Viny, RL Bowman, Y Liu, VP Lavallée, SE Eisman, W Xiao, ... Cell stem cell 25 (5), 682-696. e8, 2019 | 120 | 2019 |
Replication timing maintains the global epigenetic state in human cells KN Klein, PA Zhao, X Lyu, T Sasaki, DA Bartlett, AM Singh, I Tasan, ... Science 372 (6540), 371-378, 2021 | 118 | 2021 |
Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis K Hatzi, H Geng, AS Doane, C Meydan, R LaRiviere, M Cardenas, C Duy, ... Nature immunology 20 (1), 86-96, 2019 | 81 | 2019 |