NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis R Khandpur, C Carmona-Rivera, A Vivekanandan-Giri, A Gizinski, ... Science translational medicine 5 (178), 178ra40-178ra40, 2013 | 1341 | 2013 |
Diverse stimuli engage different neutrophil extracellular trap pathways EF Kenny, A Herzig, R Krüger, A Muth, S Mondal, PR Thompson, ... Elife 6, e24437, 2017 | 708 | 2017 |
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation HD Lewis, J Liddle, JE Coote, SJ Atkinson, MD Barker, BD Bax, KL Bicker, ... Nature chemical biology 11 (3), 189-191, 2015 | 653 | 2015 |
The structural basis of protein acetylation by the p300/CBP transcriptional coactivator X Liu, L Wang, K Zhao, PR Thompson, Y Hwang, R Marmorstein, PA Cole Nature 451 (7180), 846-850, 2008 | 507 | 2008 |
Regulation of the p300 HAT domain via a novel activation loop PR Thompson, D Wang, L Wang, M Fulco, N Pediconi, D Zhang, W An, ... Nature structural & molecular biology 11 (4), 308-315, 2004 | 491 | 2004 |
Peptidylarginine deiminase inhibition reduces vascular damage and modulates innate immune responses in murine models of atherosclerosis JS Knight, W Luo, AA O’Dell, S Yalavarthi, W Zhao, V Subramanian, ... Circulation research 114 (6), 947-956, 2014 | 417 | 2014 |
Succination inactivates gasdermin D and blocks pyroptosis F Humphries, L Shmuel-Galia, N Ketelut-Carneiro, S Li, B Wang, ... Science 369 (6511), 1633-1637, 2020 | 411 | 2020 |
Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice JS Knight, V Subramanian, AA O'Dell, S Yalavarthi, W Zhao, CK Smith, ... Annals of the rheumatic diseases 74 (12), 2199-2206, 2015 | 408 | 2015 |
Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus JS Knight, W Zhao, W Luo, V Subramanian, AA O’Dell, S Yalavarthi, ... The Journal of clinical investigation 123 (7), 2981-2993, 2013 | 388 | 2013 |
Activation of PAD4 in NET formation AS Rohrbach, DJ Slade, PR Thompson, KA Mowen Frontiers in immunology 3, 360, 2012 | 368 | 2012 |
Inhibitors and Inactivators of Protein Arginine Deiminase 4: Functional and Structural Characterization, Y Luo, K Arita, M Bhatia, B Knuckley, YH Lee, MR Stallcup, M Sato, ... Biochemistry 45 (39), 11727-11736, 2006 | 335 | 2006 |
N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis VC Willis, AM Gizinski, NK Banda, CP Causey, B Knuckley, KN Cordova, ... The Journal of Immunology 186 (7), 4396-4404, 2011 | 327 | 2011 |
Structure of an enzyme required for aminoglycoside antibiotic resistance reveals homology to eukaryotic protein kinases WC Hon, GA McKay, PR Thompson, RM Sweet, DSC Yang, GD Wright, ... Cell 89 (6), 887-895, 1997 | 297 | 1997 |
Chemical biology of protein arginine modifications in epigenetic regulation J Fuhrmann, KW Clancy, PR Thompson Chemical reviews 115 (11), 5413-5461, 2015 | 290 | 2015 |
Protein arginine deiminases and associated citrullination: physiological functions and diseases associated with dysregulation E E Witalison, P R Thompson, L J Hofseth Current drug targets 16 (7), 700-710, 2015 | 289 | 2015 |
Regulation of p53 target gene expression by peptidylarginine deiminase 4 P Li, H Yao, Z Zhang, M Li, Y Luo, PR Thompson, DS Gilmour, Y Wang Molecular and cellular biology 28 (15), 4745-4758, 2008 | 280 | 2008 |
Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential J Jones, C Causey, B Knuckley, JL Slack-Noyes, PR Thompson Current opinion in drug discovery & development 12 (5), 616, 2009 | 278 | 2009 |
The protein arginine deiminases: Structure, function, inhibition, and disease KL Bicker, PR Thompson Biopolymers 99 (2), 155-163, 2013 | 258 | 2013 |
Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis C Carmona-Rivera, PM Carlucci, E Moore, N Lingampalli, ... Science immunology 2 (10), eaag3358, 2017 | 253 | 2017 |
Kinetic characterization of protein arginine deiminase 4: a transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis PL Kearney, M Bhatia, NG Jones, L Yuan, MC Glascock, KL Catchings, ... Biochemistry 44 (31), 10570-10582, 2005 | 233 | 2005 |