Peptide stapling techniques based on different macrocyclisation chemistries YH Lau, P De Andrade, Y Wu, DR Spring Chemical Society Reviews 44 (1), 91-102, 2015 | 561 | 2015 |
Chemical sensors that incorporate click-derived triazoles YH Lau, PJ Rutledge, M Watkinson, MH Todd Chemical Society Reviews 40 (5), 2848-2866, 2011 | 446 | 2011 |
Functionalised staple linkages for modulating the cellular activity of stapled peptides YH Lau, P De Andrade, ST Quah, M Rossmann, L Laraia, N Sköld, ... Chemical science 5 (5), 1804-1809, 2014 | 207 | 2014 |
Prokaryotic nanocompartments form synthetic organelles in a eukaryote YH Lau, TW Giessen, WJ Altenburg, PA Silver Nature communications 9 (1), 1311, 2018 | 131 | 2018 |
Double strain‐promoted macrocyclization for the rapid selection of cell‐active stapled peptides YH Lau, Y Wu, M Rossmann, BX Tan, P de Andrade, YS Tan, C Verma, ... Angewandte Chemie International Edition 54 (51), 15410-15413, 2015 | 122 | 2015 |
A two-component'double-click'approach to peptide stapling YH Lau, Y Wu, P De Andrade, WRJD Galloway, DR Spring Nature Protocols 10 (4), 585-594, 2015 | 84 | 2015 |
A Click Fluorophore Sensor that Can Distinguish CuII and HgII via Selective Anion‐Induced Demetallation YH Lau, JR Price, MH Todd, PJ Rutledge Chemistry–A European Journal 17 (10), 2850-2858, 2011 | 84 | 2011 |
Investigating peptide sequence variations for ‘double-click’stapled p53 peptides YH Lau, P de Andrade, N Sköld, GJ McKenzie, AR Venkitaraman, ... Organic & biomolecular chemistry 12 (24), 4074-4077, 2014 | 73 | 2014 |
Large-scale recoding of a bacterial genome by iterative recombineering of synthetic DNA YH Lau, F Stirling, J Kuo, MAP Karrenbelt, YA Chan, A Riesselman, ... Nucleic acids research 45 (11), 6971-6980, 2017 | 70 | 2017 |
Macrocyclized extended peptides: inhibiting the substrate-recognition domain of tankyrase W Xu, YH Lau, G Fischer, YS Tan, A Chattopadhyay, M de la Roche, ... Journal of the American Chemical Society 139 (6), 2245-2256, 2017 | 69 | 2017 |
Stapled peptides as a new technology to investigate protein–protein interactions in human platelets J Iegre, NS Ahmed, JS Gaynord, Y Wu, KM Herlihy, YS Tan, ... Chemical Science 9 (20), 4638-4643, 2018 | 43 | 2018 |
Linear aliphatic dialkynes as alternative linkers for double‐click stapling of p53‐derived peptides YH Lau, P de Andrade, GJ McKenzie, AR Venkitaraman, DR Spring ChemBioChem 15 (18), 2680-2683, 2014 | 42 | 2014 |
Efficient synthesis of Fmoc-protected azido amino acids YH Lau, DR Spring Synlett 2011 (13), 1917-1919, 2011 | 38 | 2011 |
Toolbox of diverse linkers for navigating the cellular efficacy landscape of stapled peptides Y Wu, A Kaur, E Fowler, MM Wiedmann, R Young, WRJD Galloway, ... ACS Chemical Biology 14 (3), 526-533, 2019 | 36 | 2019 |
Development of a multifunctional benzophenone linker for peptide stapling and photoaffinity labelling Y Wu, LB Olsen, YH Lau, CH Jensen, M Rossmann, YR Baker, HF Sore, ... ChemBioChem 17 (8), 689-692, 2016 | 36 | 2016 |
An artificial self-assembling nanocompartment for organising metabolic pathways in yeast LC Cheah, T Stark, LSR Adamson, RS Abidin, YH Lau, F Sainsbury, ... ACS Synthetic Biology 10, 3251-3263, 2021 | 32 | 2021 |
Pore structure controls stability and molecular flux in engineered protein cages LSR Adamson, N Tasneem, MP Andreas, W Close, EN Jenner, ... Science Advances 8, abl7346, 2022 | 31 | 2022 |
Targeting the genome‐stability Hub Ctf4 by stapled‐peptide design Y Wu, F Villa, J Maman, YH Lau, L Dobnikar, AC Simon, K Labib, ... Angewandte Chemie International Edition 56 (42), 12866-12872, 2017 | 31 | 2017 |
Synthetic genome recoding: new genetic codes for new features J Kuo, F Stirling, YH Lau, Y Shulgina, JC Way, PA Silver Current genetics 64, 327-333, 2018 | 23 | 2018 |
Water-soluble, stable and azide-reactive strained dialkynes for biocompatible double strain-promoted click chemistry K Sharma, AV Strizhak, E Fowler, X Wang, W Xu, CH Jensen, Y Wu, ... Organic & Biomolecular Chemistry 17 (34), 8014-8018, 2019 | 22 | 2019 |