Patterns and severity of vincristine‐induced peripheral neuropathy in children with acute lymphoblastic leukemia EM Lavoie Smith, L Li, CW Chiang, K Thomas, RJ Hutchinson, EM Wells, ... Journal of the Peripheral Nervous System 20 (1), 37-46, 2015 | 199 | 2015 |
Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer’s disease J Fang, P Zhang, Y Zhou, CW Chiang, J Tan, Y Hou, S Stauffer, L Li, ... Nature Aging 1 (12), 1175-1188, 2021 | 118 | 2021 |
Reducing acetylated tau is neuroprotective in brain injury MK Shin, E Vázquez-Rosa, Y Koh, M Dhar, K Chaubey, CJ Cintrón-Pérez, ... Cell 184 (10), 2715-2732. e23, 2021 | 115 | 2021 |
Multimodal single-cell/nucleus RNA sequencing data analysis uncovers molecular networks between disease-associated microglia and astrocytes with implications for drug … J Xu, P Zhang, Y Huang, Y Zhou, Y Hou, LM Bekris, J Lathia, CW Chiang, ... Genome research 31 (10), 1900-1912, 2021 | 60 | 2021 |
An integrated pharmacokinetics ontology and corpus for text mining HY Wu, S Karnik, A Subhadarshini, Z Wang, S Philips, X Han, C Chiang, ... BMC bioinformatics 14, 1-15, 2013 | 58 | 2013 |
Artificial intelligence framework identifies candidate targets for drug repurposing in Alzheimer’s disease J Fang, P Zhang, Q Wang, CW Chiang, Y Zhou, Y Hou, J Xu, R Chen, ... Alzheimer's Research & Therapy 14, 1-23, 2022 | 55 | 2022 |
CYP3A5 genotype and its impact on vincristine pharmacokinetics and development of neuropathy in Kenyan children with cancer JL Skiles, CW Chiang, CH Li, S Martin, EL Smith, G Olbara, DR Jones, ... Pediatric blood & cancer 65 (3), e26854, 2018 | 50 | 2018 |
Text mining for drug–drug interaction HY Wu, CW Chiang, L Li Biomedical literature mining, 47-75, 2014 | 34 | 2014 |
Translational high‐dimensional drug interaction discovery and validation using health record databases and pharmacokinetics models CW Chiang, P Zhang, X Wang, L Wang, S Zhang, X Ning, L Shen, ... Clinical Pharmacology & Therapeutics 103 (2), 287-295, 2018 | 28 | 2018 |
Cytochrome P450 3A4*22, PPAR-α, and ARNT polymorphisms and clopidogrel response RP Kreutz, J Owens, Y Jin, P Nystrom, Z Desta, Y Kreutz, JA Breall, L Li, ... Clinical pharmacology: advances and applications, 185-192, 2013 | 27 | 2013 |
Influence of paraoxonase-1 Q192R and cytochrome P450 2C19 polymorphisms on clopidogrel response RP Kreutz, P Nystrom, Y Kreutz, J Miao, Z Desta, JA Breall, L Li, ... Clinical Pharmacology: Advances and Applications, 13-20, 2012 | 27 | 2012 |
Biomedical informatics approaches to identifying drug–drug interactions: application to insulin secretagogues X Han, CW Chiang, CE Leonard, WB Bilker, CM Brensinger, L Li, ... Epidemiology 28 (3), 459-468, 2017 | 23 | 2017 |
Graphic mining of high‐order drug interactions and their directional effects on myopathy using electronic medical records L Du, A Chakraborty, CW Chiang, L Cheng, SK Quinney, H Wu, P Zhang, ... CPT: pharmacometrics & systems pharmacology 4 (8), 481-488, 2015 | 20 | 2015 |
Translational biomedical informatics and pharmacometrics approaches in the drug interactions research P Zhang, HY Wu, CW Chiang, L Wang, S Binkheder, X Wang, D Zeng, ... CPT: pharmacometrics & systems pharmacology 7 (2), 90-102, 2018 | 19 | 2018 |
A Mixture Dose–Response Model for Identifying High‐Dimensional Drug Interaction Effects on Myopathy Using Electronic Medical Record Databases P Zhang, L Du, L Wang, M Liu, L Cheng, CW Chiang, HY Wu, SK Quinney, ... CPT: pharmacometrics & systems pharmacology 4 (8), 474-480, 2015 | 18 | 2015 |
Colorectal cancer risk is impacted by sex and type of surgery after bariatric surgery H Hussan, S Akinyeye, M Mihaylova, E McLaughlin, CW Chiang, ... Obesity Surgery 32 (9), 2880-2890, 2022 | 12 | 2022 |
Network-based translation of GWAS findings to pathobiology and drug repurposing for Alzheimer’s disease J Fang, P Zhang, Q Wang, Y Zhou, CW Chiang, R Chen, B Zhang, B Li, ... MedRxiv, 2020.01. 15.20017160, 2020 | 12 | 2020 |
Mixture drug‐count response model for the high‐dimensional drug combinatory effect on myopathy X Wang, P Zhang, CW Chiang, H Wu, L Shen, X Ning, D Zeng, L Wang, ... Statistics in medicine 37 (4), 673-686, 2018 | 12 | 2018 |
How to choose in vitro systems to predict in vivo drug clearance: a system pharmacology perspective L Wang, CW Chiang, H Liang, H Wu, W Feng, SK Quinney, J Li, L Li BioMed Research International 2015 (1), 857327, 2015 | 12 | 2015 |
Changing patterns in medication prescription for gestational diabetes during a time of guideline change in the USA: a cross‐sectional study KK Venkatesh, CW Chiang, WC Castillo, AN Battarbee, M Donneyong, ... BJOG: An International Journal of Obstetrics & Gynaecology 129 (3), 473-483, 2022 | 11 | 2022 |