Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial JM Markert, MD Medlock, SD Rabkin, GY Gillespie, T Todo, WD Hunter, ... Gene therapy 7 (10), 867-874, 2000 | 1183 | 2000 |
Intertumoral heterogeneity within medulloblastoma subgroups FMG Cavalli, M Remke, L Rampasek, J Peacock, DJH Shih, B Luu, ... Cancer cell 31 (6), 737-754. e6, 2017 | 1076 | 2017 |
Subgroup-specific structural variation across 1,000 medulloblastoma genomes PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ... Nature 488 (7409), 49-56, 2012 | 969 | 2012 |
Human cytomegalovirus infection and expression in human malignant glioma CS Cobbs, L Harkins, M Samanta, GY Gillespie, S Bharara, PH King, ... Cancer research 62 (12), 3347-3350, 2002 | 883 | 2002 |
Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme pathophysiology. CK Goldman, J Kim, WL Wong, V King, T Brock, GY Gillespie Molecular biology of the cell 4 (1), 121-133, 1993 | 684 | 1993 |
Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate CK Goldman, RL Kendall, G Cabrera, L Soroceanu, Y Heike, GY Gillespie, ... Proceedings of the National Academy of Sciences 95 (15), 8795-8800, 1998 | 565 | 1998 |
Differential susceptibility of primary and established human glioma cells to adenovirus infection: targeting via the epidermal growth factor receptor achieves fiber receptor … CR Miller, DJ Buchsbaum, PN Reynolds, JT Douglas, GY Gillespie, ... Cancer research 58 (24), 5738-5748, 1998 | 462 | 1998 |
Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBM JM Markert, PG Liechty, W Wang, S Gaston, E Braz, M Karrasch, ... Molecular Therapy 17 (1), 199-207, 2009 | 439 | 2009 |
Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors JN Parker, GY Gillespie, CE Love, S Randall, RJ Whitley, JM Markert Proceedings of the National Academy of Sciences 97 (5), 2208-2213, 2000 | 396 | 2000 |
HuR, a RNA stability factor, is expressed in malignant brain tumors and binds to adenine-and uridine-rich elements within the 3′ untranslated regions of cytokine and … LB Nabors, GY Gillespie, L Harkins, PH King Cancer research 61 (5), 2154-2161, 2001 | 392 | 2001 |
Vascular endothelial growth factor in human glioma cell lines: induced secretion by EGF, PDGF-BB, and bFGF JC Tsai, CK Goldman, GY Gillespie Journal of neurosurgery 82 (5), 864-873, 1995 | 374 | 1995 |
Inhibition of cystine uptake disrupts the growth of primary brain tumors WJ Chung, SA Lyons, GM Nelson, H Hamza, CL Gladson, GY Gillespie, ... Journal of Neuroscience 25 (31), 7101-7110, 2005 | 365 | 2005 |
Receptor for interleukin 13 is a marker and therapeutic target for human high-grade gliomas W Debinski, DM Gibo, SW Hulet, JR Connor, GY Gillespie Clinical Cancer Research 5 (5), 985-990, 1999 | 333 | 1999 |
Differential gene expression profiling in human brain tumors JM MARKERT, CM FULLER, GY GILLESPIE, JK BUBIEN, LEEA McLEAN, ... Physiological genomics 5 (1), 21-33, 2001 | 300 | 2001 |
Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins S Andreansky, B He, J Van Cott, J McGhee, JM Markert, GY Gillespie, ... Gene therapy 5 (1), 121-130, 1998 | 299 | 1998 |
A phase 1 trial of oncolytic HSV-1, G207, given in combination with radiation for recurrent GBM demonstrates safety and radiographic responses JM Markert, SN Razdan, HC Kuo, A Cantor, A Knoll, M Karrasch, ... Molecular Therapy 22 (5), 1048-1055, 2014 | 298 | 2014 |
CD133 is a marker of bioenergetic stress in human glioma CE Griguer, CR Oliva, E Gobin, P Marcorelles, DJ Benos, JR Lancaster Jr, ... PloS one 3 (11), e3655, 2008 | 293 | 2008 |
Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a scid mouse model of human malignant glioma. R Chambers, GY Gillespie, L Soroceanu, S Andreansky, S Chatterjee, ... Proceedings of the National Academy of Sciences 92 (5), 1411-1415, 1995 | 280 | 1995 |
The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors. SS Andreansky, B He, GY Gillespie, L Soroceanu, J Markert, J Chou, ... Proceedings of the National Academy of Sciences 93 (21), 11313-11318, 1996 | 263 | 1996 |
Brain edema in meningiomas is associated with increased vascular endothelial growth factor expression CK Goldman, S Bharara, CA Palmer, J Vitek, JC Tsai, HL Weiss, ... Neurosurgery 40 (6), 1269-1277, 1997 | 257 | 1997 |