Unraveling comparative anti-amyloidogenic behavior of pyrazinamide and D-cycloserine: a mechanistic biophysical insight SK Chaturvedi, N Zaidi, P Alam, JM Khan, A Qadeer, IA Siddique, ... PloS one 10 (8), e0136528, 2015 | 89 | 2015 |
CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s disease Nature Communication, 2020 | 50 | 2020 |
Inhibitory growth evaluation and apoptosis induction in MCF-7 cancer cells by new 5-aryl-2-butylthio-1, 3, 4-oxadiazole derivatives R Khanam, K Ahmad, II Hejazi, IA Siddique, V Kumar, AR Bhat, A Azam, ... Cancer Chemotherapy and Pharmacology 80, 1027-1042, 2017 | 29 | 2017 |
Molecular basis of the inhibition and disaggregation of thermally-induced amyloid fibrils of human serum albumin by an anti-Parkinson's drug, benserazide hydrochloride TI Chandel, A Masroor, MK Siddiqi, IA Siddique, I Jahan, M Ali, ... Journal of Molecular Liquids 278, 553-567, 2019 | 26 | 2019 |
Development of a Novel Electrochemiluminescence ELISA for Quantification of α-Synuclein Phosphorylated at Ser129 in Biological Samples S Dutta, S Hornung, HB Taha, K Biggs, I Siddique, LM Chamoun, ... ACS Chemical Neuroscience 14 (7), 1238-1248, 2023 | 21 | 2023 |
mTOR inhibition with Sirolimus in multiple system atrophy: a randomized, double‐blind, placebo‐controlled futility trial and 1‐year biomarker longitudinal analysis JA Palma, J Martinez, P Millar Vernetti, T Ma, MA Perez, J Zhong, Y Qian, ... Movement Disorders 37 (4), 778-789, 2022 | 21 | 2022 |
The molecular tweezer CLR01 improves behavioral deficits and reduces tau pathology in P301S-tau transgenic mice J Di, I Siddique, Z Li, G Malki, S Hornung, S Dutta, I Hurst, E Ishaaya, ... Alzheimer's research & therapy 13, 1-20, 2021 | 21 | 2021 |
Anti-parkinsonian l-dopa can also act as anti-systemic amyloidosis—A mechanistic exploration S Nusrat, N Zaidi, MK Siddiqi, M Zaman, IA Siddique, MR Ajmal, ... International journal of biological macromolecules 99, 630-640, 2017 | 18 | 2017 |
An insight into the inhibition of fibrillation process verses disaggregation of preformed fibrils of bovine serum albumin by isoprenaline hydrochloride TI Chandel, M Afghani, A Masroor, IA Siddique, SM Zakariya, M Ali, ... International journal of biological macromolecules 154, 1448-1459, 2020 | 16 | 2020 |
A multiparametric analysis of the synergistic impact of anti-Parkinson's drugs on the fibrillation of human serum albumin TI Chandel, N Zaidi, M Zaman, I Jahan, A Masroor, IA Siddique, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1867 (3), 275-285, 2019 | 15 | 2019 |
A routinely used protein staining dye acts as an inhibitor of wild type and mutant alpha-synuclein aggregation and modulator of neurotoxicity N Ahsan, IA Siddique, S Gupta, A Surolia European Journal of Medicinal Chemistry 143, 1174-1184, 2018 | 14 | 2018 |
Prion protein transcription is auto-regulated through dynamic interactions with G-quadruplex motifs in its own promoter P Pradhan, A Srivastava, J Singh, B Biswas, A Saini, I Siddique, P Kumari, ... Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1863 (3), 194479, 2020 | 11 | 2020 |
Lysine-selective molecular tweezers are cell penetrant and concentrate in lysosomes Z Li, I Siddique, I Hadrović, A Kirupakaran, J Li, Y Zhang, FG Klärner, ... Communications biology 4 (1), 1076, 2021 | 10 | 2021 |
Molecular tweezers: supramolecular hosts with broad-spectrum biological applications H Shahpasand-Kroner, I Siddique, R Malik, GR Linares, MI Ivanova, ... Pharmacological Reviews 75 (2), 263-308, 2023 | 9 | 2023 |
Exophers are components of mammalian cell neurobiology in health and disease I Siddique, J Di, CK Williams, D Markovic, HV Vinters, G Bitan bioRxiv, 2021.12. 06.471479, 2021 | 7 | 2021 |
ARL6IP5 ameliorates α-synuclein burden by inducing autophagy via preventing ubiquitination and degradation of ATG12 I Siddique, K Kamble, S Gupta, K Solanki, S Bhola, N Ahsan, S Gupta International Journal of Molecular Sciences 24 (13), 10499, 2023 | 6 | 2023 |
Different inhibitors of Aβ42-induced toxicity have distinct metal-ion dependency AJ Mason, I Hurst, R Malik, I Siddique, I Solomonov, I Sagi, FG Klärner, ... ACS chemical neuroscience 11 (15), 2243-2255, 2020 | 2 | 2020 |
Osteocalcin Alters Aggregation Pattern of Abeta42 to Form Complexes (Ao) that Aid in Amyloid Reduction in Mouse Models of Alzheimer Disease SG Viji Vijayan1,2, Ibrar Ahmad Siddique1, Sakshi Gupta1, Evanka Madan ... Preprint, 2024 | | 2024 |
New blood-based biomarkers for Sanfilippo syndrome G Bitan, HB Taha, I Siddique, LM Chamoun, K Mohseni, AJ Morris, ... Molecular Genetics and Metabolism 141 (2), 107775, 2024 | | 2024 |
COMPOUND MODULATING GSK-3 ACTIVITY Sarika Gupta, Ibrar Siddique, Aishwarya Nilakhe US Patent US, 11,820,764 B2, 2023 | | 2023 |