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IBRAR SIDDIQUE
IBRAR SIDDIQUE
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Unraveling comparative anti-amyloidogenic behavior of pyrazinamide and D-cycloserine: a mechanistic biophysical insight
SK Chaturvedi, N Zaidi, P Alam, JM Khan, A Qadeer, IA Siddique, ...
PloS one 10 (8), e0136528, 2015
892015
CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s disease
Nature Communication, 2020
502020
Inhibitory growth evaluation and apoptosis induction in MCF-7 cancer cells by new 5-aryl-2-butylthio-1, 3, 4-oxadiazole derivatives
R Khanam, K Ahmad, II Hejazi, IA Siddique, V Kumar, AR Bhat, A Azam, ...
Cancer Chemotherapy and Pharmacology 80, 1027-1042, 2017
292017
Molecular basis of the inhibition and disaggregation of thermally-induced amyloid fibrils of human serum albumin by an anti-Parkinson's drug, benserazide hydrochloride
TI Chandel, A Masroor, MK Siddiqi, IA Siddique, I Jahan, M Ali, ...
Journal of Molecular Liquids 278, 553-567, 2019
262019
Development of a Novel Electrochemiluminescence ELISA for Quantification of α-Synuclein Phosphorylated at Ser129 in Biological Samples
S Dutta, S Hornung, HB Taha, K Biggs, I Siddique, LM Chamoun, ...
ACS Chemical Neuroscience 14 (7), 1238-1248, 2023
212023
mTOR inhibition with Sirolimus in multiple system atrophy: a randomized, double‐blind, placebo‐controlled futility trial and 1‐year biomarker longitudinal analysis
JA Palma, J Martinez, P Millar Vernetti, T Ma, MA Perez, J Zhong, Y Qian, ...
Movement Disorders 37 (4), 778-789, 2022
212022
The molecular tweezer CLR01 improves behavioral deficits and reduces tau pathology in P301S-tau transgenic mice
J Di, I Siddique, Z Li, G Malki, S Hornung, S Dutta, I Hurst, E Ishaaya, ...
Alzheimer's research & therapy 13, 1-20, 2021
212021
Anti-parkinsonian l-dopa can also act as anti-systemic amyloidosis—A mechanistic exploration
S Nusrat, N Zaidi, MK Siddiqi, M Zaman, IA Siddique, MR Ajmal, ...
International journal of biological macromolecules 99, 630-640, 2017
182017
An insight into the inhibition of fibrillation process verses disaggregation of preformed fibrils of bovine serum albumin by isoprenaline hydrochloride
TI Chandel, M Afghani, A Masroor, IA Siddique, SM Zakariya, M Ali, ...
International journal of biological macromolecules 154, 1448-1459, 2020
162020
A multiparametric analysis of the synergistic impact of anti-Parkinson's drugs on the fibrillation of human serum albumin
TI Chandel, N Zaidi, M Zaman, I Jahan, A Masroor, IA Siddique, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1867 (3), 275-285, 2019
152019
A routinely used protein staining dye acts as an inhibitor of wild type and mutant alpha-synuclein aggregation and modulator of neurotoxicity
N Ahsan, IA Siddique, S Gupta, A Surolia
European Journal of Medicinal Chemistry 143, 1174-1184, 2018
142018
Prion protein transcription is auto-regulated through dynamic interactions with G-quadruplex motifs in its own promoter
P Pradhan, A Srivastava, J Singh, B Biswas, A Saini, I Siddique, P Kumari, ...
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1863 (3), 194479, 2020
112020
Lysine-selective molecular tweezers are cell penetrant and concentrate in lysosomes
Z Li, I Siddique, I Hadrović, A Kirupakaran, J Li, Y Zhang, FG Klärner, ...
Communications biology 4 (1), 1076, 2021
102021
Molecular tweezers: supramolecular hosts with broad-spectrum biological applications
H Shahpasand-Kroner, I Siddique, R Malik, GR Linares, MI Ivanova, ...
Pharmacological Reviews 75 (2), 263-308, 2023
92023
Exophers are components of mammalian cell neurobiology in health and disease
I Siddique, J Di, CK Williams, D Markovic, HV Vinters, G Bitan
bioRxiv, 2021.12. 06.471479, 2021
72021
ARL6IP5 ameliorates α-synuclein burden by inducing autophagy via preventing ubiquitination and degradation of ATG12
I Siddique, K Kamble, S Gupta, K Solanki, S Bhola, N Ahsan, S Gupta
International Journal of Molecular Sciences 24 (13), 10499, 2023
62023
Different inhibitors of Aβ42-induced toxicity have distinct metal-ion dependency
AJ Mason, I Hurst, R Malik, I Siddique, I Solomonov, I Sagi, FG Klärner, ...
ACS chemical neuroscience 11 (15), 2243-2255, 2020
22020
Osteocalcin Alters Aggregation Pattern of Abeta42 to Form Complexes (Ao) that Aid in Amyloid Reduction in Mouse Models of Alzheimer Disease
SG Viji Vijayan1,2, Ibrar Ahmad Siddique1, Sakshi Gupta1, Evanka Madan ...
Preprint, 2024
2024
New blood-based biomarkers for Sanfilippo syndrome
G Bitan, HB Taha, I Siddique, LM Chamoun, K Mohseni, AJ Morris, ...
Molecular Genetics and Metabolism 141 (2), 107775, 2024
2024
COMPOUND MODULATING GSK-3 ACTIVITY
Sarika Gupta, Ibrar Siddique, Aishwarya Nilakhe
US Patent US, 11,820,764 B2, 2023
2023
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