SRD5A3 is required for converting polyprenol to dolichol and is mutated in a congenital glycosylation disorder V Cantagrel, DJ Lefeber, BG Ng, Z Guan, JL Silhavy, SL Bielas, L Lehle, ... Cell 142 (2), 203-217, 2010 | 335 | 2010 |
Visualization of eukaryotic DNA mismatch repair reveals distinct recognition and repair intermediates H Hombauer, CS Campbell, CE Smith, A Desai, RD Kolodner Cell 147 (5), 1040-1053, 2011 | 225 | 2011 |
New insights into the mechanism of DNA mismatch repair GX Reyes, TT Schmidt, RD Kolodner, H Hombauer Chromosoma 124, 443-462, 2015 | 148 | 2015 |
A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo T Fellner, DH Lackner, H Hombauer, P Piribauer, I Mudrak, K Zaragoza, ... Genes & development 17 (17), 2138-2150, 2003 | 144 | 2003 |
Mismatch repair, but not heteroduplex rejection, is temporally coupled to DNA replication H Hombauer, A Srivatsan, CD Putnam, RD Kolodner Science 334 (6063), 1713-1716, 2011 | 136 | 2011 |
Generation of active protein phosphatase 2A is coupled to holoenzyme assembly H Hombauer, D Weismann, I Mudrak, C Stanzel, T Fellner, DH Lackner, ... PLoS biology 5 (6), e155, 2007 | 126 | 2007 |
Identification of a subunit of a novel kleisin-β/SMC complex as a potential substrate of protein phosphatase 2A FM Yeong, H Hombauer, KS Wendt, T Hirota, I Mudrak, K Mechtler, ... Current biology 13 (23), 2058-2064, 2003 | 123 | 2003 |
PCNA and Msh2-Msh6 activate an Mlh1-Pms1 endonuclease pathway required for Exo1-independent mismatch repair EM Goellner, CE Smith, CS Campbell, H Hombauer, A Desai, CD Putnam, ... Molecular cell 55 (2), 291-304, 2014 | 111 | 2014 |
Checkpoint kinases regulate a global network of transcription factors in response to DNA damage EJ Jaehnig, D Kuo, H Hombauer, TG Ideker, RD Kolodner Cell reports 4 (1), 174-188, 2013 | 84 | 2013 |
Selective interactions between epithelial tumour cells and bone marrow mesenchymal stem cells. H Hombauer, J Minguell Br J Cancer. 2000 Apr;82(7):1290-6. 82 (7), 1290-1296, 2000 | 71 | 2000 |
Dominant Mutations in S. cerevisiae PMS1 Identify the Mlh1-Pms1 Endonuclease Active Site and an Exonuclease 1-Independent Mismatch Repair Pathway CE Smith, ML Mendillo, N Bowen, H Hombauer, CS Campbell, A Desai, ... PLoS genetics 9 (10), e1003869, 2013 | 70 | 2013 |
Cdc28/Cdk1 positively and negatively affects genome stability in S. cerevisiae JM Enserink, H Hombauer, ME Huang, RD Kolodner Journal of cell biology 185 (3), 423-437, 2009 | 52 | 2009 |
Mlh2 Is an Accessory Factor for DNA Mismatch Repair in Saccharomyces cerevisiae CS Campbell, H Hombauer, A Srivatsan, N Bowen, K Gries, A Desai, ... PLoS genetics 10 (5), e1004327, 2014 | 47 | 2014 |
Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis TT Schmidt, G Reyes, K Gries, CÜ Ceylan, S Sharma, M Meurer, M Knop, ... Proceedings of the National Academy of Sciences 114 (22), E4442-E4451, 2017 | 42 | 2017 |
Extensive 5′-surveillance guards against non-canonical NAD-caps of nuclear mRNAs in yeast Y Zhang, D Kuster, T Schmidt, D Kirrmaier, G Nübel, D Ibberson, V Benes, ... Nature Communications 11 (1), 5508, 2020 | 37 | 2020 |
A genetic screen pinpoints ribonucleotide reductase residues that sustain dNTP homeostasis and specifies a highly mutagenic type of dNTP imbalance TT Schmidt, S Sharma, GX Reyes, K Gries, M Gross, B Zhao, JH Yuan, ... Nucleic acids research 47 (1), 237-252, 2019 | 26 | 2019 |
Ligation of newly replicated DNA controls the timing of DNA mismatch repair GX Reyes, A Kolodziejczak, LJPS Devakumar, T Kubota, RD Kolodner, ... Current Biology 31 (6), 1268-1276. e6, 2021 | 24 | 2021 |
Visualization of mismatch repair complexes using fluorescence microscopy TT Schmidt, H Hombauer DNA repair 38, 58-67, 2016 | 21 | 2016 |
Inactivation of folylpolyglutamate synthetase Met7 results in genome instability driven by an increased dUTP/dTTP ratio TT Schmidt, S Sharma, GX Reyes, A Kolodziejczak, T Wagner, B Luke, ... Nucleic acids research 48 (1), 264-277, 2020 | 15 | 2020 |
Mitochondrial genotype and risk for Alzheimer's disease: cross-sectional data from the Vienna-Transdanube-Aging "VITA" study. HK Mostafaie N, Rossmanith W, Hombauer H, Dechat T, Raffelsberger T, Bauer K ... J Neural Transm 111 (9), 1155-1165., 2004 | 13 | 2004 |