Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2 J Huo, A Le Bas, RR Ruza, HME Duyvesteyn, H Mikolajek, T Malinauskas, ... Nature structural & molecular biology 27 (9), 846-854, 2020 | 491 | 2020 |
A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19 J Huo, H Mikolajek, A Le Bas, JJ Clark, P Sharma, A Kipar, J Dormon, ... Nature communications 12 (1), 5469, 2021 | 115 | 2021 |
Chlamydiae Assemble a Pathogen Synapse to Hijack the Host Endoplasmic Reticulum M Dumoux, DK Clare, HR Saibil, RD Hayward Traffic 13 (12), 1612-1627, 2012 | 92 | 2012 |
Basal foot MTOC organizes pillar MTs required for coordination of beating cilia DK Clare, J Magescas, T Piolot, M Dumoux, C Vesque, E Pichard, T Dang, ... Nature communications 5 (1), 4888, 2014 | 88 | 2014 |
Plasma FIB milling for the determination of structures in situ C Berger, M Dumoux, T Glen, NB Yee, JM Mitchels, Z Patáková, ... Nature communications 14 (1), 629, 2023 | 55 | 2023 |
A Chlamydia effector recruits CEP170 to reprogram host microtubule organization M Dumoux, A Menny, D Delacour, RD Hayward Journal of cell science 128 (18), 3420-3434, 2015 | 54 | 2015 |
Pathogen-sugar interactions revealed by universal saturation transfer analysis CJ Buchanan, B Gaunt, PJ Harrison, Y Yang, J Liu, A Khan, AM Giltrap, ... Science 377 (6604), eabm3125, 2022 | 30 | 2022 |
Direct imaging of the recruitment and phosphorylation of S6K1 in the mTORC1 pathway in living cells AR Ahmed, RJ Owens, CD Stubbs, AW Parker, R Hitchman, RB Yadav, ... Scientific Reports 9 (1), 3408, 2019 | 27 | 2019 |
Making connections: snapshots of chlamydial type III secretion systems in contact with host membranes M Dumoux, A Nans, HR Saibil, RD Hayward Current opinion in microbiology 23, 1-7, 2015 | 20 | 2015 |
Penicillin kills Chlamydia following the fusion of bacteria with lysosomes and prevents genital inflammatory lesions in C. muridarum-infected mice M Dumoux, SM Le Gall, M Habbeddine, C Delarbre, RD Hayward, ... PloS one 8 (12), e83511, 2013 | 20 | 2013 |
Cryo-plasma FIB/SEM volume imaging of biological specimens M Dumoux, T Glen, JLR Smith, EML Ho, LMA Perdigão, A Pennington, ... Elife 12, e83623, 2023 | 19 | 2023 |
Membrane contact sites between pathogen-containing compartments and host organelles M Dumoux, RD Hayward Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016 | 19 | 2016 |
Correlation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes H Mikolajek, M Weckener, ZF Brotzakis, J Huo, EV Dalietou, A Le Bas, ... Proceedings of the National Academy of Sciences 119 (31), e2205412119, 2022 | 17 | 2022 |
Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2 (vol 27, pg 846, 2020) J Huo, A Le Bas, RR Ruza, HME Duyvesteyn, H Mikolajek, T Malinauskas, ... Nature Structural & Molecular Biology 27 (11), 1094-1094, 2020 | 17 | 2020 |
The Legionella effector WipB is a translocated Ser/Thr phosphatase that targets the host lysosomal nutrient sensing machinery MS Prevost, N Pinotsis, M Dumoux, RD Hayward, G Waksman Scientific Reports 7 (1), 9450, 2017 | 13 | 2017 |
Transient transfection and expression of eukaryotic membrane proteins in Expi293F cells and their screening on a small scale: application for structural studies GO Krasnoselska, M Dumoux, N Gamage, H Cheruvara, J Birch, ... Structural Proteomics: High-Throughput Methods, 105-128, 2021 | 11 | 2021 |
Structural characterisation of a nanobody derived from a naïve library that neutralises SARS-CoV-2 J Huo, AL Bas, RR Ruza, HM Duyvesteyn, H Mikolajek, T Malinauskas, ... | 8 | 2020 |
Parakeet: a digital twin software pipeline to assess the impact of experimental parameters on tomographic reconstructions for cryo-electron tomography JM Parkhurst, M Dumoux, M Basham, D Clare, CA Siebert, T Varslot, ... Open Biology 11 (10), 210160, 2021 | 7 | 2021 |
Cryptic pathogen-sugar interactions revealed by universal saturation transfer analysis CJ Buchanan, B Gaunt, PJ Harrison, Y Yang, J Liu, A Khan, AM Giltrap, ... BioRxiv, 2021.04. 14.439284, 2021 | 7 | 2021 |
Correlative imaging using super‐resolution fluorescence microscopy and soft X‐ray tomography at cryogenic temperatures provides a new way to assess virosome solutions for … CA Okolo, A Jadhav, P Phillips, M Dumoux, AA McMurray, VD Joshi, ... Journal of Microscopy 284 (3), 214-232, 2021 | 6 | 2021 |