AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner AP Seabright, NHF Fine, JP Barlow, SO Lord, I Musa, A Gray, JA Bryant, ... The FASEB Journal 34 (5), 6284, 2020 | 121 | 2020 |
Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics J Ast, A Arvaniti, NHF Fine, D Nasteska, FB Ashford, Z Stamataki, ... Nature Communications 11 (1), 467, 2020 | 99 | 2020 |
PDX1LOW MAFALOW β-cells contribute to islet function and insulin release D Nasteska, NHF Fine, FB Ashford, F Cuozzo, K Viloria, G Smith, A Dahir, ... Nature communications 12 (1), 674, 2021 | 68 | 2021 |
Androgen excess in pancreatic β cells and neurons predisposes female mice to type 2 diabetes G Navarro, C Allard, JJ Morford, W Xu, S Liu, AJR Molinas, SM Butcher, ... JCI insight 3 (12), 2018 | 66 | 2018 |
Glucocorticoids reprogram β-cell signaling to preserve insulin secretion NHF Fine, CL Doig, YS Elhassan, NC Vierra, P Marchetti, M Bugliani, ... Diabetes 67 (2), 278-290, 2018 | 66 | 2018 |
Optical control of L-type Ca2+ channels using a diltiazem photoswitch T Fehrentz, FME Huber, N Hartrampf, T Bruegmann, JA Frank, NHF Fine, ... Nature chemical biology 14 (8), 764-767, 2018 | 54 | 2018 |
Optical control of GPR40 signalling in pancreatic β-cells JA Frank, DA Yushchenko, NHF Fine, M Duca, M Citir, J Broichhagen, ... Chemical science 8 (11), 7604-7610, 2017 | 47 | 2017 |
Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes SR Sayers, RL Beavil, NHF Fine, GC Huang, P Choudhary, KJ Pacholarz, ... Diabetologia 63, 313-323, 2020 | 38 | 2020 |
Conditional and reversible activation of class A and BG protein-coupled receptors using tethered pharmacology T Podewin, J Ast, J Broichhagen, NHF Fine, D Nasteska, P Leippe, ... ACS Central Science 4 (2), 166-179, 2018 | 30 | 2018 |
Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice ZB Mehta, N Fine, TJ Pullen, MC Cane, M Hu, P Chabosseau, G Meur, ... American Journal of Physiology-Endocrinology and Metabolism 311 (2), E488-E507, 2016 | 27 | 2016 |
Vitamin-D-binding protein contributes to the maintenance of α cell function and glucagon secretion K Viloria, D Nasteska, LJB Briant, S Heising, DP Larner, NHF Fine, ... Cell Reports 31 (11), 2020 | 25 | 2020 |
Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone T Podewin, J Broichhagen, C Frost, D Groneberg, J Ast, H Meyer-Berg, ... Chemical Science 8 (6), 4644-4653, 2017 | 25 | 2017 |
Revealing the tissue-level complexity of endogenous glucagon-like peptide-1 receptor expression and signaling J Ast, D Nasteska, NHF Fine, DJ Nieves, Z Koszegi, Y Lanoiselée, ... Nature communications 14 (1), 301, 2023 | 12 | 2023 |
Expanded LUXendin color palette for GLP1R detection and visualization in vitro and in vivo J Ast, AN Novak, T Podewin, NHF Fine, B Jones, A Tomas, R Birke, ... JACS Au 2 (4), 1007-1017, 2022 | 12 | 2022 |
Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis SN Mousavy Gharavy, BM Owen, SJ Millership, P Chabosseau, G Pizza, ... Diabetologia 64, 850-864, 2021 | 12 | 2021 |
The effect of ex vivo human serum from liver disease patients on cellular protein synthesis and growth SL Allen, AP Seabright, JI Quinlan, A Dhaliwal, FR Williams, NHF Fine, ... Cells 11 (7), 1098, 2022 | 11 | 2022 |
Dimerization of the sodium/iodide symporter RJ Thompson, A Fletcher, K Brookes, H Nieto, MM Alshahrani, ... Thyroid 29 (10), 1485-1498, 2019 | 10 | 2019 |
LUXendins reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics J Ast, A Arvaniti, NHF Fine, D Nasteska, FB Ashford, Z Stamataki, ... bioRxiv, 557132, 2019 | 3 | 2019 |
Mature and immature β-cells both contribute to islet function and insulin release D Nasteska, N Fine, F Ashford, F Cuozzo, K Viloria, G Smith, A Dahir, ... | 2 | 2020 |
Author Correction: Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics J Ast, A Arvaniti, NHF Fine, D Nasteska, FB Ashford, Z Stamataki, ... Nature Communications 11 (1), 5160, 2020 | 1 | 2020 |