Neoadjuvant oncolytic virotherapy before surgery sensitizes triple-negative breast cancer to immune checkpoint therapy MC Bourgeois-Daigneault, DG Roy, AS Aitken, N El Sayes, NT Martin, ... Science translational medicine 10 (422), eaao1641, 2018 | 305 | 2018 |
Hypoxia-driven immune escape in the tumor microenvironment A Vito, N El-Sayes, K Mossman Cells 9 (4), 992, 2020 | 198 | 2020 |
Tumor heterogeneity: a great barrier in the age of cancer immunotherapy N El-Sayes, A Vito, K Mossman Cancers 13 (4), 806, 2021 | 108 | 2021 |
Multi-modal potentiation of oncolytic virotherapy by vanadium compounds M Selman, C Rousso, A Bergeron, HH Son, R Krishnan, NA El-Sayes, ... Molecular Therapy 26 (1), 56-69, 2018 | 85 | 2018 |
Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses A Banerjee, N El-Sayes, P Budylowski, RA Jacob, D Richard, H Maan, ... IScience 24 (5), 2021 | 49 | 2021 |
De novo necroptosis creates an inflammatory environment mediating tumor susceptibility to immune checkpoint inhibitors ST Workenhe, A Nguyen, D Bakhshinyan, J Wei, DN Hare, KL MacNeill, ... Communications biology 3 (1), 645, 2020 | 40 | 2020 |
First-in-class small molecule potentiators of cancer virotherapy MH Dornan, R Krishnan, AM Macklin, M Selman, N El Sayes, HH Son, ... Scientific reports 6 (1), 26786, 2016 | 40 | 2016 |
Mechanisms of PD-L1 regulation in malignant and virus-infected cells H Farrukh, N El-Sayes, K Mossman International Journal of Molecular Sciences 22 (9), 4893, 2021 | 19 | 2021 |
Assessing the completeness of reporting in preclinical oncolytic virus therapy studies DA Fergusson, NL Wesch, GJ Leung, JL MacNeil, I Conic, J Presseau, ... Molecular Therapy-Oncolytics 14, 179-187, 2019 | 19 | 2019 |
Immune checkpoint blockade in triple negative breast cancer influenced by B cells through myeloid-derived suppressor cells A Vito, O Salem, N El-Sayes, IP MacFawn, AL Portillo, K Milne, ... Communications Biology 4 (1), 859, 2021 | 17 | 2021 |
Combined radionuclide therapy and immunotherapy for treatment of triple negative breast cancer A Vito, S Rathmann, N Mercanti, N El-Sayes, K Mossman, J Valliant International journal of molecular sciences 22 (9), 4843, 2021 | 14 | 2021 |
A combination of chemotherapy and oncolytic virotherapy sensitizes colorectal adenocarcinoma to immune checkpoint inhibitors in a cDC1-dependent manner N El-Sayes, A Vito, O Salem, ST Workenhe, Y Wan, K Mossman International Journal of Molecular Sciences 23 (3), 1754, 2022 | 13 | 2022 |
Oncolytic BHV-1 is sufficient to induce immunogenic cell death and synergizes with low-dose chemotherapy to dampen immunosuppressive T regulatory cells ME Davola, O Cormier, A Vito, N El-Sayes, S Collins, O Salem, S Revill, ... Cancers 15 (4), 1295, 2023 | 6 | 2023 |
IFNAR blockade synergizes with oncolytic VSV to prevent virus-mediated PD-L1 expression and promote antitumor T cell activity N El-Sayes, S Walsh, A Vito, A Reihani, K Ask, Y Wan, K Mossman Molecular Therapy-Oncolytics 25, 16-30, 2022 | 5 | 2022 |
Tumor Heterogeneity: A Great Barrier in the Age of Cancer Immunotherapy. Cancers 2021, 13, 806 N El-Sayes, A Vito, K Mossman s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021 | 2 | 2021 |
Genetic modification of oncolytic viruses to enhance antitumor immunity ME Davola, A Vito, J Wei, N El-Sayes, S Workenhe, KL Mossman Methods in Enzymology 635, 231-250, 2020 | 2 | 2020 |
Response to FEC Chemotherapy and Oncolytic HSV-1 Is Associated with Macrophage Polarization and Increased Expression of S100A8/A9 in Triple Negative Breast Cancer A Vito, N El-Sayes, O Salem, Y Wan, KL Mossman Cancers 13 (21), 5590, 2021 | 1 | 2021 |
Early temporal dynamics of cellular responses to SARS-CoV-2 A Banerjee, P Budylowski, D Richard, H Maan, JA Aguiar, N El-Sayes, ... bioRxiv, 2020.06. 18.158154, 2020 | 1 | 2020 |
Small Molecule Potentiators of Oncolytic Virus Therapy Suppress the Innate Antiviral Response N El-Sayes Université d'Ottawa/University of Ottawa, 2018 | 1 | 2018 |
Blockade of ifn signaling during cancer vaccination Y Wan, S Walsh, N El-Sayes US Patent App. 17/990,480, 2023 | | 2023 |